9 research outputs found
Students’ Perceptions of Justice: Application of Sanctions, Guilt, and Responsibility in Campus Sexual Assault Cases
Despite growing attention to adjudication of campus sexual assault cases, little is known how students perceive “justice” for such cases. The present study examined whether victim, perpetrator, and assault characteristics influenced students’ perceptions of: whether a sanctionable violation occurred; the type of sanction to be applied; perceived severity of the sanction; proportion of guilt attributable to the victim and perpetrator; and level of responsibility of the victim and perpetrator. Fourteen factors pertaining to potential negative evaluation of rape victims were derived; thus, a non-factorial vignette survey design focusing only on each main effect was employed. 846 college students responded to one of four versions of a randomly distributed survey each containing eight vignettes that varied to represent all levels of the 14 factors. Students were not consistent in their application of sanctions or assignment of guilt or responsibility for the sexual assault vignettes, but rather were influenced in their ratings for 10 of the 14 factors. Students responded differentially to levels of the following factors: psychological impact on the victim, victim’s medical consequences, reason for the victim’s incapacitation leading to assault, consistency of victim’s and perpetrator’s accounts of the assault, sexual orientation of the victim, type of forced sex, number of perpetrators involved, fraternity membership of the perpetrator, gender of the perpetrator, and victim’s initial display of sexual interest in the perpetrator. Cases consistent with rape myths appear to influence students’ perceptions of justice. Findings are discussed in terms of implications for research and prevention programming
The clinical outcome of second generation anti-hormonal therapy in patients with metastatic castrate-resistant prostate cancer following CHAARTED regimen.
Are College Students’ Attitudes Related to Their Application of Sanctions for Campus Sexual Assault Cases?
With growing attention to adjudication of campus sexual assault cases, more is known regarding students’ views of sexual assault, but little the literature focuses on how students perceive “justice” in terms of assigning sanctions or guilt/responsibility for such cases. The present study focused on understanding whether college students’ preformed attitudes and beliefs were associated with the severity of sanctions they applied across a range of sexual assault cases as well as their assignments of guilt and responsibility to the parties involved. To determine students’ attitudes and beliefs mediating effects on sanction choices, five scales (i.e., rape myth acceptance, downplaying the severity of rape, sexism, just world beliefs, and right-wing authoritarianism) were adapted and used for this project. College students (n = 846) responded to one of four versions of a randomly distributed survey each containing eight vignettes varied to represent levels of 14 factors employed because of their relevance to campus sexual assault cases. Across all versions, sexism was associated with increased responsibility given to the victim. In addition, stronger endorsement of both downplaying significance of rape and rape myth acceptance scales were associated with giving a milder sanction to the perpetrator and increased responsibility and guilt assigned to the victim. Just world beliefs and right-wing authoritarianism associations were inconsistent across the four versions, suggesting these beliefs were situation-specific. Preformed attitudes that are more directly related to the context of sexual assault influenced the designation of sanctions applied to perpetrators and perceptions of guilt and responsibility. Findings are discussed in terms of implications for research and prevention programming
Students’ Perceptions of Justice: Application of Sanctions, Guilt, and Responsibility in Campus Sexual Assault Cases
Despite growing attention to adjudication of campus sexual assault cases, little is known how students perceive “justice” for such cases. The present study examined whether victim, perpetrator, and assault characteristics influenced students’ perceptions of: whether a sanctionable violation occurred; the type of sanction to be applied; perceived severity of the sanction; proportion of guilt attributable to the victim and perpetrator; and level of responsibility of the victim and perpetrator. Fourteen factors pertaining to potential negative evaluation of rape victims were derived; thus, a non-factorial vignette survey design focusing only on each main effect was employed. 846 college students responded to one of four versions of a randomly distributed survey each containing eight vignettes that varied to represent all levels of the 14 factors. Students were not consistent in their application of sanctions or assignment of guilt or responsibility for the sexual assault vignettes, but rather were influenced in their ratings for 10 of the 14 factors. Students responded differentially to levels of the following factors: psychological impact on the victim, victim’s medical consequences, reason for the victim’s incapacitation leading to assault, consistency of victim’s and perpetrator’s accounts of the assault, sexual orientation of the victim, type of forced sex, number of perpetrators involved, fraternity membership of the perpetrator, gender of the perpetrator, and victim’s initial display of sexual interest in the perpetrator. Cases consistent with rape myths appear to influence students’ perceptions of justice. Findings are discussed in terms of implications for research and prevention programming
In Vitro Framework to Assess the Anti-Helicobacter pylori Potential of Lactic Acid Bacteria Secretions as Alternatives to Antibiotics
Helicobacter pylori is a prevalent bacterium that can cause gastric ulcers and cancers. Lactic acid bacteria (LAB) ameliorate treatment outcomes against H. pylori, suggesting that they could be a source of bioactive molecules usable as alternatives to current antibiotics for which resistance is mounting. We developed an in vitro framework to compare the anti-H. pylori properties of 25 LAB and their secretions against H. pylori. All studies were done at acidic and neutralized pH, with or without urea to mimic various gastric compartments. Eighteen LAB strains secreted molecules that curtailed the growth of H. pylori and the activity was urea-resistant in five LAB. Several LAB supernatants also reduced the urease activity of H. pylori. Pre-treatment of H. pylori with acidic LAB supernatants abrogated its flagella-mediated motility and decreased its ability to elicit pro-inflammatory IL-8 cytokine from human gastric cells, without reverting the H. pylori-induced repression of other pro-inflammatory cytokines. This study identified the LAB that have the most anti-H. pylori effects, decreasing its viability, its production of virulence factors, its motility and/or its ability to elicit pro-inflammatory IL-8 from gastric cells. Once identified, these molecules can be used as alternatives or complements to current antibiotics to fight H. pylori infections
Intravenous thiotepa for treatment of breast cancer-related leptomeningeal carcinomatosis: case series
Regulation of Insulin-Response Element Binding Protein-1 in Obesity and Diabetes: Potential Role in Impaired Insulin-Induced Gene Transcription
One of the major mechanisms by which insulin modulates glucose homeostasis is through regulation of gene expression. Therefore, reduced expression of transcription factors that are required for insulin-regulated gene expression may contribute to insulin resistance. We recently identified insulin response element-binding protein-1 (IRE-BP1) as a transcription factor that binds and transactivates multiple insulin-responsive genes, but the regulation of IRE-BP1 in vivo is largely unknown. In this study, we show that IRE-BP1 interacts with the insulin response sequence of the IGF-I, IGFBP-1, and IGFBP-3 genes using chromatin immunoprecipitation assay. Furthermore, activation by IRE-BP1 is sequence specific and mimics that of the insulin effect on gene transcription. Tissue expression of IRE-BP1 is 50- to 200-fold higher in classical insulin target compared with nontarget tissues in lean animals, with a significantly reduced level of expression in the skeletal muscle and adipose tissue in obese and diabetic animals. In the liver, IRE-BP1 is localized to the nucleus in lean rats but is sequestered to the cytoplasm in obese and diabetic animals. Cytoplasmic sequestration appears to be related to inhibition of insulin-mediated phosphatidylinositol-3 kinase signaling. Therefore, in diabetes and obesity, the mechanisms involved in reducing the transactivation of the insulin response sequence by IRE-BP1 include decreased gene transcription and nuclear exclusion to prevent DNA binding. Our study supports the notion that IRE-BP1 may be relevant to the action of insulin in vivo and may play a role in the development of insulin resistance and diabetes
Abstracts of International Conference on Innovations in Business Management
This book contains abstracts of the various research ideas of the academic community and practitioners of management presented at the International Conference on Innovations in Business Management (ICIBM 2020). The researchers have contributed toward various themes of the conference such as sustainable economy, supply chain, women-empowerment, export-import, microfinance, government policies, etc. We strongly believe that it will open up further scope for in-depth research in various disciplines of business management. Best wishes to the participants to have detailed discussions on the above-said wide range of areas.
Conference Title: International Conference on Innovations in Business ManagementConference Acronym: ICIBM 2020Conference Date: 16-17 January 2020Conference Location: ICFAI University, Dehradun, IndiaConference Organizers: ICFAI Business School, ICFAI University, Dehradun, India & University of Derby, United Kingdo