Evidence of a link between the evolution of clusters and their AGN fraction

We discuss the optical properties, X-ray detections and active galactic nucleus (AGN) populations of four clusters at z ~ 1 in the Subaru–XMM Deep Field (SXDF). The velocity distribution and plausible extended X-ray detections are examined, as well as the number of X-ray point sources and radio sources associated with the clusters. We find that the two clusters that appear virialized and have an extended X-ray detection contain few, if any, AGN, whereas the two pre-virialized clusters have a large AGN population. This constitutes evidence that the AGN fraction in clusters is linked to the clusters' evolutionary stage. The number of X-ray AGN in the pre-virialized clusters is consistent with an overdensity of a factor of ~200; the radio AGN appear to be clustered with a factor of 3 to 6 higher. The median K-band luminosities of L_K= 1.7 ± 0.7 L* for the X-ray sources and L_K= 2.3 ± 0.1 L* for the radio sources support the theory that these AGN are triggered by galaxy interaction and merging events in sub-groups with low internal velocity distributions, which make up the cluster environment in a pre-virialization evolutionary stage

Veterinary drug therapies used for undesirable behaviours in UK dogs under primary veterinary care

Undesirable behaviours (UBs) in dogs are common and important issues with serious potential welfare consequences for both the dogs and their owners. This study aimed to investigate the usage of drug therapy for UBs in dogs and assess demographic risk factors for drug-prescribed UBs within the dog population under primary-care veterinary care in the UK in 2013. Dogs receiving drug therapy for UB were identified through the retrospective analysis of anonymised electronic patient records in VetCompass™. Risk factor analysis used multivariable logistic regression modelling. The study population comprised 103,597 dogs under veterinary care in the UK during 2013. There were 413 drug-prescribed UBs recorded among 404 dogs. The prevalence of dogs with at least one UB event treated with a drug in 2013 was 0.4%. Multivariable modelling identified 3 breeds with increased odds of drug-prescribed UB compared with crossbred dogs: Toy Poodle (OR 2.75), Tibetan Terrier (OR 2.68) and Shih-tzu (OR 1.95). Increasing age was associated with increased odds of drug-prescribed UB, with dogs ≥ 12 years showing 3.1 times the odds compared with dogs < 3 years. Neutered males (OR 1.82) and entire males (OR 1.50) had increased odds compared with entire females. The relatively low prevalence of dogs with at least one UB event that was treated with a drug in 2013 could suggest that opportunities for useful psychopharmaceutical intervention in UBs may be being missed in first opinion veterinary practice. While bodyweight was not a significant factor, the 3 individual breeds at higher odds of an UB treated with a behaviour modifying drug all have a relatively low average bodyweight. The current results also support previous research of a male predisposition to UBs and it is possible that this higher risk resulted in the increased likelihood of being prescribed a behaviour modifying drug, regardless of neuter status

kD-STR : a method for spatio-temporal data reduction and modelling

Analysing and learning from spatio-temporal datasets is an important process in many domains, including transportation, healthcare and meteorology. In particular, data collected by sensors in the environment allows us to understand and model the processes acting within the environment. Recently, the volume of spatio-temporal data collected has increased significantly, presenting several challenges for data scientists. Methods are therefore needed to reduce the quantity of data that needs to be processed in order to analyse and learn from spatio-temporal datasets. In this article, we present the -Dimensional Spatio-Temporal Reduction method (D-STR) for reducing the quantity of data used to store a dataset whilst enabling multiple types of analysis on the reduced dataset. D-STR uses hierarchical partitioning to find spatio-temporal regions of similar instances, and models the instances within each region to summarise the dataset. We demonstrate the generality of D-STR with three datasets exhibiting different spatio-temporal characteristics and present results for a range of data modelling techniques. Finally, we compare D-STR with other techniques for reducing the volume of spatio-temporal data. Our results demonstrate that D-STR is effective in reducing spatio-temporal data and generalises to datasets that exhibit different properties

Complete Genome Sequence of Streptococcus pneumoniae Strain BVJ1JL, a Serotype 1 Carriage Isolate from Malawi.

Streptococcus pneumoniae is a leading cause of pneumonia, meningitis, and bacteremia. Serotype 1 is rarely carried but is commonly associated with invasive pneumococcal disease, and in the African "meningitis belt," it is prone to cause cyclical epidemics. We report the complete genome sequence of S. pneumoniae serotype 1 strain BVJ1JL, isolated in Malawi

The role of breast milk fortifier in the post-discharge nutrition of preterm infants

Infants born prematurely are often discharged from hospital before 37 weeks post menstrual age. While breastfeeding will meet all the nutritional requirements of full-term infants, these preterm infants may need enhanced levels of protein, minerals and possibly energy to ensure optimum growth, bone mineralisation and neurological development. To meet these additional nutrient needs in the neonatal unit, it is currently recommended that multinutrient breast milk fortifier is added to maternal breast milk. There may also be benefits in continuing to provide fortified milk after discharge, potentially including improved growth and preserving breastfeeding, and this is increasingly becoming a recognised practice in some neonatal units. This article presents the discussion and consensus of a multidisciplinary panel of neonatologists, neonatal dietitians, a GP and a neonatal outreach nurse. The aim is to develop guidance on providing safe and effective nutritional supplementation for preterm infants after discharge in order to maintain optimal growth. This guidance is aimed at community healthcare staff and is based on the limited evidence available, using shared best practice and expertise