Runaway electron diagnostics for the COMPASS tokamak using EC emission

An electron cyclotron emission (ECE) diagnostic of suprathermal electrons was utilised for runaway electron (RE) experiments purposes in the COMPASS tokamak. Our vertical ECE (V-ECE) system consists of a 16-channel heterodyne radiometer and an E-band horn antenna with a 76.5-88 GHz frequency range front-end. Simulations used for the design of the diagnostic showed a possibility of detecting the emission of low-energy (50-140 keV) runaway electrons. We realized measurements with both extraordinary (X-) and ordinary (O-) mode linear polarizations. The amplitudes of the X-mode and O-mode signals are similar, which can be explained by depolarised reflected radiation. V-ECE measurements in low-density flattop discharges and in discharges with massive gas injections of high-Z elements show correlations with other RE diagnostics. Our results are in the agreement with the principles of the primary runaway generation mechanisms

Runaway electron diagnostics for the COMPASS tokamak using EC emission

An electron cyclotron emission (ECE) diagnostic of suprathermal electrons was utilised for runaway electron (RE) experiments purposes in the COMPASS tokamak. Our vertical ECE (V-ECE) system consists of a 16-channel heterodyne radiometer and an E-band horn antenna with a 76.5-88 GHz frequency range front-end. Simulations used for the design of the diagnostic showed a possibility of detecting the emission of low-energy (50-140 keV) runaway electrons. We realized measurements with both extraordinary (X-) and ordinary (O-) mode linear polarizations. The amplitudes of the X-mode and O-mode signals are similar, which can be explained by depolarised reflected radiation. V-ECE measurements in low-density flattop discharges and in discharges with massive gas injections of high-Z elements show correlations with other RE diagnostics. Our results are in the agreement with the principles of the primary runaway generation mechanisms

Lasioglossins LLIII affect the morphogenesis of Candida albicans and reduces the duration of experimental vaginal candidiasis in mice

Lasioglossins are a group of peptides with identified antimicrobial activity. The inhibitory effects of two synthetic lasioglossin derivatives, LLIII and D-isomeric variant LLIII-D, on morphological changes in Candida albicans in vitro and the effect of local administration of LLIII during experimental murine candidiasis were investigated. C. albicans blastoconidia were grown in the presence of lasioglossin LLIII or LLIII-D at concentrations of 11.5M and 21M, respectively, for 1, 2 and 3 days and their viability determined by flow cytometry using eosin Y staining. Morphological changes were examined by light and fluorescent microscopy. The Candida-inhibitory effect of daily intravaginal administration of 0.7 or 1.4g of LLIII was assessed in mice with experimentally-induced vaginal candidiasis. LLIII and LLIII-D lasioglossins exhibited candidacidal activity in vitro (>76% after 24 hr and >84% after 48hr of incubation). After 72hr incubation of Candida with low concentration of lasioglossins, an increase in viability was detected, probably due to a Candida antimicrobial peptides evasion strategy. Furthermore, lasioglossins inhibited temperature-induced morphotype changes toward hyphae and pseudohyphae with sporadic occurrence of atypical cells with two or enlarged nuclei, suggesting interference with mitosis or cytokinesis. Local application of LLIII reduced the duration of experimental candidiasis with no evidence of adverse effects. Lasioglossin LLIII is a promising candidate for development as an antimicrobial drug for treating the vaginal candidiasis

Long slide-away discharges in the COMPASS tokamak

In this contribution, long runaway electron (RE)dominated discharges achieved in the COMPASS tokamak are presented. The extensivelength is possible due to a low consumption of available volt-seconds of thetokamak transformer in this type of discharge. Energetic electron losses in thisregime seems to be modulated mainly by small oscillations of a radial position (controllersetting) unlike in the RE discharges at higher electron density, where variousMHD phenomena affect the evolution of the losses. The behaviour of the slide-awayplasma is studied using magnetic coils, HXR detectors, ECE system and a pair of3He proportional counters of neutrons. The plasma scenario is also modelled usingFokker-Planck codes

Overview of the COMPASS results

International audienc