1,689 research outputs found
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Framing a bilateral US-Russian geologic repository initiative
This document summarizes a framework for the development of a bilateral United StatesïżœRussian geologic repository initiative to enable cooperative work on the science and technology of geologic disposal of high-level nuclear wastes and fissile-containing materials. Three different types of integrated technical activities in Russia are employed to focus and organize a Department of Energy (DOE) Office of Civilian Radioactive Waste Management (RW) FY00 initiative. We have specified the items for initial negotiations with the Russians for start-up activities in FY99 and early FY00. These first interactions will generate other activities which, by utilizing Russiaïżœs unique capabilities, may assist us in the development and validation of the US geologic repository program. The current International Science and Technology Center (ISTC) cooperative study of 30years of heat effects on underground hardrock rock media at the closed city of Krasnoyarsk-26 (Zheleznorgorsk) is but one example of such a Russian geologic repository analogue project that may assist the US geologic repository program
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Development of a Comprehensive Plan for Scientific Research, Exploration, and Design: Creation of an Undergroung Radioactive Waste Isloation Facility at the Nizhnekansky Rock Massif
ISTC Partner Project No.2377, ''Development of a General Research and Survey Plan to Create an Underground RW Isolation Facility in Nizhnekansky Massif'', funded a group of key Russian experts in geologic disposal, primarily at Federal State Unitary Enterprise All-Russian Design and Research Institute of Engineering Production (VNIPIPT) and Mining Chemical Combine Krasnoyarsk-26 (MCC K-26) (Reference 1). The activities under the ISTC Partner Project were targeted to the creation of an underground research laboratory which was to justify the acceptability of the geologic conditions for ultimate isolation of high-level waste in Russia. In parallel to this project work was also under way with Minatom's financial support to characterize alternative sections of the Nizhnekansky granitoid rock massif near the MCC K-26 site to justify the possibility of creating an underground facility for long-term or ultimate isolation of radioactive waste (RW) and spent nuclear fuel (SNF). (Reference 2) The result was a synergistic, integrated set of activities several years that advanced the geologic repository site characterization and development of a proposed underground research laboratory better than could have been expected with only the limited funds from ISTC Partner Project No.2377 funded by the U.S. DOE-RW. There were four objectives of this ISTC Partner Project 2377 geologic disposal work: (1) Generalize and analyze all research work done previously at the Nizhnekansky granitoid massif by various organizations; (2) Prepare and issue a declaration of intent (DOI) for proceeding with an underground research laboratory in a granite massif near the MCC K-26 site. (The DOI is similar to a Record of Decision in U.S. terminology). (3) Proceeding from the data obtained as a result of scientific research and exploration and design activities, prepare a justification of investment (JOI) for an underground research laboratory in as much detail as the available site characterization data allow. Consider the possibility of the substantiated selection of a specific site for the underground laboratory at this stage. (The JOI is similar to an advanced conceptual design or preliminary design in U.S. terminology). (4) Perform a preliminary safety assessment of the geologic isolation of radioactive waste and unreprocessable spent nuclear fuel (SNF) in the Nizhnekansky massif. Significant progress has been made toward fulfilling the joint project objectives. The results were documented in a series of quarterly reports and one final report over a period of {approx}2 3/4 years
Excision for simplicial sheaves on the Stein site and Gromov's Oka principle
A complex manifold satisfies the Oka-Grauert property if the inclusion
\Cal O(S,X) \hookrightarrow \Cal C(S,X) is a weak equivalence for every Stein
manifold , where the spaces of holomorphic and continuous maps from to
are given the compact-open topology. Gromov's Oka principle states that if
has a spray, then it has the Oka-Grauert property. The purpose of this
paper is to investigate the Oka-Grauert property using homotopical algebra. We
embed the category of complex manifolds into the model category of simplicial
sheaves on the site of Stein manifolds. Our main result is that the Oka-Grauert
property is equivalent to representing a finite homotopy sheaf on the Stein
site. This expresses the Oka-Grauert property in purely holomorphic terms,
without reference to continuous maps.Comment: Version 3 contains a few very minor improvement
Quasi-elastic peak lineshapes in adsorbate diffusion on nearly flat surfaces at low coverages: the motional narrowing effect in Xe on Pt(111)
Quasi-elastic helium atom scattering measurements have provided clear
evidence for a two-dimensional free gas of Xe atoms on Pt(111) at low
coverages. Increasing the friction due to the surface, a gradual change of the
shape of the quasi-elastic peak is predicted and analyzed for this system in
terms of the so-called motional narrowing effect. The type of analysis
presented here for the quasi-elastic peak should be prior to any deconvolution
procedure carried out in order to better extract information from the process,
e.g. diffusion coefficients and jump distributions. Moreover, this analysis
also provides conditions for the free gas regime different than those reported
earlier.Comment: 12 pages, 4 figures (revised version
On morphological hierarchical representations for image processing and spatial data clustering
Hierarchical data representations in the context of classi cation and data
clustering were put forward during the fties. Recently, hierarchical image
representations have gained renewed interest for segmentation purposes. In this
paper, we briefly survey fundamental results on hierarchical clustering and
then detail recent paradigms developed for the hierarchical representation of
images in the framework of mathematical morphology: constrained connectivity
and ultrametric watersheds. Constrained connectivity can be viewed as a way to
constrain an initial hierarchy in such a way that a set of desired constraints
are satis ed. The framework of ultrametric watersheds provides a generic scheme
for computing any hierarchical connected clustering, in particular when such a
hierarchy is constrained. The suitability of this framework for solving
practical problems is illustrated with applications in remote sensing
Coronal structure of the cTTS V2129 Oph
The nature of the magnetic coupling between T Tauri stars and their disks
determines not only the mass accretion process but possibly the spin evolution
of the central star. We have taken a recently-published surface magnetogram of
one moderately-accreting T Tauri star (V2129 Oph) and used it to extrapolate
the geometry of its large-scale field. We determine the structure of the open
(wind-bearing) field lines, the closed (X-ray bright) field lines and those
potentially accreting field lines that pass through the equatorial plane inside
the Keplerian co-rotation radius. We consider a series of models in which the
stellar magnetic field is opened up by the outward pressure of the hot coronal
gas at a range of radii. As this radius is increased, accretion takes place
along simpler field structures and impacts on fewer sites at the stellar
surface. This is consistent with the observed variation in the Ca II IRT and
HeI lines which suggests that accretion in the visible hemisphere is confined
to a single high-latitude spot. By determining the density and velocity of the
accretion flows, we find that in order to have most of the total mass accretion
rate impacting on a single high-latitude region we need disk material to
accrete from approximately 7R*, close to the Keplerian co-rotation radius at
6.8R*. We also calculate the coronal density and X-ray emission measure. We
find that both the magnitude and rotational modulation of the emission measure
increase as the source surface is increased. For the field structure of V2129
Oph which is dominantly octupolar, the emission forms a bright, high-latitude
ring that is always in view as the star rotates. Since the accretion funnels
are not dense enough to cause significant scattering of coronal X-ray photons,
they provide only a low rotational modulation of around 10% at most.Comment: 10 pages, 9 figure
Electrostatic potential at the alpha carbon atoms along the alpha helices and beta strands.
We present here analysis of pre-calculated values for the electrostatic potential at the alpha carbons, previously stored in the STING_RDB.PABMB
Trial of aerosolised surfactant for preterm infants with respiratory distress syndrome
Objective To evaluate the safety of an aerosolised surfactant, SF-RI 1, administered via nasal continuous positive airway pressure (nCPAP) and a prototype breath synchronisation device (AeroFact), to preterm infants with respiratory distress syndrome (RDS). Design Multicentre, open-label, dose-escalation study with historical controls. Setting Newborn intensive care units at Mater Mothers' Hospital, Brisbane, and Royal Hospital for Women, Sydney, Australia. Patients Infants 26 weeks through 30 weeks gestation who required nCPAP 6-8 cmH 2 O and fraction of inspired oxygen (FiO 2) 2.4, nCPAP >8 cmH 2 O, arterial carbon dioxide >65 mm Hg, pH <7.20 or three severe apnoeas within 6 hours during the first 72 hours of life. Other outcomes included tolerance of the AeroFact treatment and complications of prematurity. Results 10 infants were enrolled in part 1 and 21 in part 2 and were compared with 93 historical controls. No safety issues were identified. In part 2, 6 of 21 (29%) AeroFact-treated infants compared with 30 of 63 (48%) control infants met failure criteria. Kaplan-Meier analysis of patients in part 2 showed a trend towards decreased rate of study failure in the AeroFact-treated infants compared with historical controls (p=0.10). Conclusion The AeroFact system can safely deliver aerosolised surfactant to preterm infants with RDS who are on nCPAP. Trial registration number ACTRN12617001458325
Signature contact coordination patterns for secondary structure elements in protein structures.
We present here analysis of pre-calculated values for the cross-links, previously stored in the STING_RDB.PABMB
Studying structure function relationship of proteins using "remediated" PDB files.
We have invested a significant amount of time and CPU resources in order to curate and analyze what ate the consequences for in-silico analysis of the active site 3D environment after implementing remediated PDB files to STING_DB and STING interface.PABMB
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