Framing a bilateral US-Russian geologic repository initiative

This document summarizes a framework for the development of a bilateral United States�Russian geologic repository initiative to enable cooperative work on the science and technology of geologic disposal of high-level nuclear wastes and fissile-containing materials. Three different types of integrated technical activities in Russia are employed to focus and organize a Department of Energy (DOE) Office of Civilian Radioactive Waste Management (RW) FY00 initiative. We have specified the items for initial negotiations with the Russians for start-up activities in FY99 and early FY00. These first interactions will generate other activities which, by utilizing Russia�s unique capabilities, may assist us in the development and validation of the US geologic repository program. The current International Science and Technology Center (ISTC) cooperative study of 30years of heat effects on underground hardrock rock media at the closed city of Krasnoyarsk-26 (Zheleznorgorsk) is but one example of such a Russian geologic repository analogue project that may assist the US geologic repository program

Development of a Comprehensive Plan for Scientific Research, Exploration, and Design: Creation of an Undergroung Radioactive Waste Isloation Facility at the Nizhnekansky Rock Massif

ISTC Partner Project No.2377, ''Development of a General Research and Survey Plan to Create an Underground RW Isolation Facility in Nizhnekansky Massif'', funded a group of key Russian experts in geologic disposal, primarily at Federal State Unitary Enterprise All-Russian Design and Research Institute of Engineering Production (VNIPIPT) and Mining Chemical Combine Krasnoyarsk-26 (MCC K-26) (Reference 1). The activities under the ISTC Partner Project were targeted to the creation of an underground research laboratory which was to justify the acceptability of the geologic conditions for ultimate isolation of high-level waste in Russia. In parallel to this project work was also under way with Minatom's financial support to characterize alternative sections of the Nizhnekansky granitoid rock massif near the MCC K-26 site to justify the possibility of creating an underground facility for long-term or ultimate isolation of radioactive waste (RW) and spent nuclear fuel (SNF). (Reference 2) The result was a synergistic, integrated set of activities several years that advanced the geologic repository site characterization and development of a proposed underground research laboratory better than could have been expected with only the limited funds from ISTC Partner Project No.2377 funded by the U.S. DOE-RW. There were four objectives of this ISTC Partner Project 2377 geologic disposal work: (1) Generalize and analyze all research work done previously at the Nizhnekansky granitoid massif by various organizations; (2) Prepare and issue a declaration of intent (DOI) for proceeding with an underground research laboratory in a granite massif near the MCC K-26 site. (The DOI is similar to a Record of Decision in U.S. terminology). (3) Proceeding from the data obtained as a result of scientific research and exploration and design activities, prepare a justification of investment (JOI) for an underground research laboratory in as much detail as the available site characterization data allow. Consider the possibility of the substantiated selection of a specific site for the underground laboratory at this stage. (The JOI is similar to an advanced conceptual design or preliminary design in U.S. terminology). (4) Perform a preliminary safety assessment of the geologic isolation of radioactive waste and unreprocessable spent nuclear fuel (SNF) in the Nizhnekansky massif. Significant progress has been made toward fulfilling the joint project objectives. The results were documented in a series of quarterly reports and one final report over a period of {approx}2 3/4 years

Excision for simplicial sheaves on the Stein site and Gromov's Oka principle

A complex manifold $X$ satisfies the Oka-Grauert property if the inclusion \Cal O(S,X) \hookrightarrow \Cal C(S,X) is a weak equivalence for every Stein manifold $S$, where the spaces of holomorphic and continuous maps from $S$ to $X$ are given the compact-open topology. Gromov's Oka principle states that if $X$ has a spray, then it has the Oka-Grauert property. The purpose of this paper is to investigate the Oka-Grauert property using homotopical algebra. We embed the category of complex manifolds into the model category of simplicial sheaves on the site of Stein manifolds. Our main result is that the Oka-Grauert property is equivalent to $X$ representing a finite homotopy sheaf on the Stein site. This expresses the Oka-Grauert property in purely holomorphic terms, without reference to continuous maps.Comment: Version 3 contains a few very minor improvement

Quasi-elastic peak lineshapes in adsorbate diffusion on nearly flat surfaces at low coverages: the motional narrowing effect in Xe on Pt(111)

Quasi-elastic helium atom scattering measurements have provided clear evidence for a two-dimensional free gas of Xe atoms on Pt(111) at low coverages. Increasing the friction due to the surface, a gradual change of the shape of the quasi-elastic peak is predicted and analyzed for this system in terms of the so-called motional narrowing effect. The type of analysis presented here for the quasi-elastic peak should be prior to any deconvolution procedure carried out in order to better extract information from the process, e.g. diffusion coefficients and jump distributions. Moreover, this analysis also provides conditions for the free gas regime different than those reported earlier.Comment: 12 pages, 4 figures (revised version

On morphological hierarchical representations for image processing and spatial data clustering

Hierarchical data representations in the context of classi cation and data clustering were put forward during the fties. Recently, hierarchical image representations have gained renewed interest for segmentation purposes. In this paper, we briefly survey fundamental results on hierarchical clustering and then detail recent paradigms developed for the hierarchical representation of images in the framework of mathematical morphology: constrained connectivity and ultrametric watersheds. Constrained connectivity can be viewed as a way to constrain an initial hierarchy in such a way that a set of desired constraints are satis ed. The framework of ultrametric watersheds provides a generic scheme for computing any hierarchical connected clustering, in particular when such a hierarchy is constrained. The suitability of this framework for solving practical problems is illustrated with applications in remote sensing

Coronal structure of the cTTS V2129 Oph

The nature of the magnetic coupling between T Tauri stars and their disks determines not only the mass accretion process but possibly the spin evolution of the central star. We have taken a recently-published surface magnetogram of one moderately-accreting T Tauri star (V2129 Oph) and used it to extrapolate the geometry of its large-scale field. We determine the structure of the open (wind-bearing) field lines, the closed (X-ray bright) field lines and those potentially accreting field lines that pass through the equatorial plane inside the Keplerian co-rotation radius. We consider a series of models in which the stellar magnetic field is opened up by the outward pressure of the hot coronal gas at a range of radii. As this radius is increased, accretion takes place along simpler field structures and impacts on fewer sites at the stellar surface. This is consistent with the observed variation in the Ca II IRT and HeI lines which suggests that accretion in the visible hemisphere is confined to a single high-latitude spot. By determining the density and velocity of the accretion flows, we find that in order to have most of the total mass accretion rate impacting on a single high-latitude region we need disk material to accrete from approximately 7R*, close to the Keplerian co-rotation radius at 6.8R*. We also calculate the coronal density and X-ray emission measure. We find that both the magnitude and rotational modulation of the emission measure increase as the source surface is increased. For the field structure of V2129 Oph which is dominantly octupolar, the emission forms a bright, high-latitude ring that is always in view as the star rotates. Since the accretion funnels are not dense enough to cause significant scattering of coronal X-ray photons, they provide only a low rotational modulation of around 10% at most.Comment: 10 pages, 9 figure

Electrostatic potential at the alpha carbon atoms along the alpha helices and beta strands.

We present here analysis of pre-calculated values for the electrostatic potential at the alpha carbons, previously stored in the STING_RDB.PABMB

Trial of aerosolised surfactant for preterm infants with respiratory distress syndrome

Objective To evaluate the safety of an aerosolised surfactant, SF-RI 1, administered via nasal continuous positive airway pressure (nCPAP) and a prototype breath synchronisation device (AeroFact), to preterm infants with respiratory distress syndrome (RDS). Design Multicentre, open-label, dose-escalation study with historical controls. Setting Newborn intensive care units at Mater Mothers' Hospital, Brisbane, and Royal Hospital for Women, Sydney, Australia. Patients Infants 26 weeks through 30 weeks gestation who required nCPAP 6-8 cmH 2 O and fraction of inspired oxygen (FiO 2) 2.4, nCPAP >8 cmH 2 O, arterial carbon dioxide >65 mm Hg, pH <7.20 or three severe apnoeas within 6 hours during the first 72 hours of life. Other outcomes included tolerance of the AeroFact treatment and complications of prematurity. Results 10 infants were enrolled in part 1 and 21 in part 2 and were compared with 93 historical controls. No safety issues were identified. In part 2, 6 of 21 (29%) AeroFact-treated infants compared with 30 of 63 (48%) control infants met failure criteria. Kaplan-Meier analysis of patients in part 2 showed a trend towards decreased rate of study failure in the AeroFact-treated infants compared with historical controls (p=0.10). Conclusion The AeroFact system can safely deliver aerosolised surfactant to preterm infants with RDS who are on nCPAP. Trial registration number ACTRN12617001458325

Signature contact coordination patterns for secondary structure elements in protein structures.

We present here analysis of pre-calculated values for the cross-links, previously stored in the STING_RDB.PABMB

Studying structure function relationship of proteins using "remediated" PDB files.

We have invested a significant amount of time and CPU resources in order to curate and analyze what ate the consequences for in-silico analysis of the active site 3D environment after implementing remediated PDB files to STING_DB and STING interface.PABMB