Sosialisasi Anak dalam Masyarakat di Kelurahan Airtiris Kecamatan Kampar Kabupaten Kampar

This thesis put forward in order to achieve a degree qualified strata 1 (S1) Sociology.By title SOCIALIZATION OF CHILDREN IN VILLGE COMUNITIES AIRTIRIS DISTRICTS KAMPAR DISTRICT KAMPAR . Kelurahan Airtiris have a tradition that still survive, namely Tradition nujuh Monthly, Aqikah, Down Bath and Khitanan. But over the development period of this tradition began less done or made in whole the like where appropriate. Issues raised in this issue is 1. What are the values inherited in the child socialization patterns during pregnancy after givibirth and adolescence, 2. How do rite performed in the process of socialization of children in the community pattern Airtiris Kampar Kampar Regency. pattern Airtiris Kampar Kampar Regency. The method used is qualitative research methods. The research location in the village Airtiris Kampar Kampar District. That is the subject of this research is the community of parents who have children. The method used is qualitative research methods. The research location in the village Airtiris Kampar Kampar District. That is the subject of this research is the community of parents who have children. Keywords: Tradition Society Airtiris, children in villge, Airtiris Keywords: Tradition Society Airtiris, children in villge, Airtiri

Repeated Bursts from Relativistic Scattering of Compact Objects in Galactic Nuclei

Galactic nuclei are densely populated by stellar mass compact objects such as black holes and neutron stars. Bound, highly eccentric binaries form as a result of gravitational wave (GW) losses during close flybys between these objects. We study the evolution of these systems using 2.5 and 3.5 order post-Newtonian equations of motion. The GW signal consists of many thousand repeated bursts (RB) for minutes to days (depending on the impact parameter and masses), followed by a powerful GW chirp and an eccentric merger. We show that a significant signal to noise ratio (SNR) accumulates already in the RB phase, corresponding to a detection limit around 200-300 Mpc and 300--600 Mpc for Advanced LIGO for an average orientation BH/NS or BH/BH binary, respectively. The theoretical errors introduced by the inaccuracy of the PN templates are typically much less severe for the RB phase than in the following eccentric merger. The GW signal in the RB phase is broadband; we show that encounters involving intermediate mass black holes are detectable in multiple frequency bands coincidentally using LIGO and LISA.Comment: 16 pages, 10 figures, version accepted for publication in Physical Review

Curing singularities: From the big bang to black holes

Singular spacetimes are a natural prediction of Einstein's theory. Most memorable are the singular centers of black holes and the big bang. However, dilatonic extensions of Einstein's theory can support nonsingular spacetimes. The cosmological singularities can be avoided by dilaton driven inflation. Furthermore, a nonsingular black hole can be constructed in two dimensions.Comment: To appear as a brief report in Phys. Rev.

A Test of Multisession Automatic Action Tendency Retraining to Reduce Alcohol Consumption Among Young Adults in the Context of a Human Laboratory Paradigm.

BACKGROUND: Young adult heavy drinking is an important public health concern. Current interventions have efficacy but with only modest effects, and thus, novel interventions are needed. In prior studies, heavy drinkers, including young adults, have demonstrated stronger automatically triggered approach tendencies to alcohol-related stimuli than lighter drinkers. Automatic action tendency retraining has been developed to correct this tendency and consequently reduce alcohol consumption. This study is the first to test multiple iterations of automatic action tendency retraining, followed by laboratory alcohol self-administration. METHODS: A total of 72 nontreatment-seeking, heavy drinking young adults ages 21 to 25 were randomized to automatic action tendency retraining or a control condition (i.e., sham training ). Of these, 69 (54% male) completed 4 iterations of retraining or the control condition over 5 days with an alcohol drinking session on Day 5. Self-administration was conducted according to a human laboratory paradigm designed to model individual differences in impaired control (i.e., difficulty adhering to limits on alcohol consumption). RESULTS: Automatic action tendency retraining was not associated with greater reduction in alcohol approach tendency or less alcohol self-administration than the control condition. The laboratory paradigm was probably sufficiently sensitive to detect an effect of an experimental manipulation given the range of self-administration behavior observed, both in terms of number of alcoholic and nonalcoholic drinks and measures of drinking topography. CONCLUSIONS: Automatic action tendency retraining was ineffective among heavy drinking young adults without motivation to change their drinking. Details of the retraining procedure may have contributed to the lack of a significant effect. Despite null primary findings, the impaired control laboratory paradigm is a valid laboratory-based measure of young adult alcohol consumption that provides the opportunity to observe drinking topography and self-administration of nonalcoholic beverages (i.e., protective behavioral strategies directly related to alcohol use)

Prospective Evaluation of Pregnancy-Associated Plasma Protein-A and Outcomes in Patients With Acute Coronary Syndromes

ObjectivesThis study sought to investigate whether pregnancy-associated plasma protein-A (PAPP-A) is useful for risk assessment in non–ST-segment elevation acute coronary syndrome (NSTE-ACS).BackgroundPAPP-A is a high molecular weight, zinc-binding metalloproteinase that is associated with vulnerable plaque and may be a predictor of cardiovascular disease and mortality.MethodsWe measured PAPP-A at baseline in 3,782 patients with non NSTE-ACS randomized to ranolazine or placebo in the MERLIN–TIMI 36 (Metabolic Efficiency With Ranolazine for Less Ischemia in Non-ST Elevation Acute Coronary Syndromes) trial and followed for an average of 1 year. A cut point of 6.0 μIU/ml was chosen from pilot work in this cohort.ResultsPAPP-A >6.0 μIU/ml at presentation was associated with higher rates of cardiovascular death (CVD) or myocardial infarction (MI) at 30 days (7.4% vs. 3.7%, hazard ratio [HR]: 2.01; 95% confidence interval [CI]: 1.43 to 2.82; p < 0.001) and at 1 year (14.9% vs. 9.7%, HR: 1.63; 95% CI: 1.29 to 2.05; p < 0.001). PAPP-A was also associated with higher rates of CVD (HR: 1.94; 95% CI: 1.07 to 3.52, p = 0.027) and myocardial infarction (HR: 1.82; 95% CI: 1.22 to 2.71, p = 0.003) individually at 30 days. There was no difference in the risk associated with PAPP-A stratified by baseline cardiac troponin I [Accu-TnI >0.04 μg/l], p interaction = 0.87). After adjustment for cardiac troponin I, ST-segment deviation, age, sex, diabetes, smoking, hypertension, and coronary artery disease, PAPP-A was independently associated with CVD/myocardial infarction at 30 days (adjusted HR: 1.62, 95% CI: 1.15 to 2.29; p = 0.006) and 1 year (adjusted HR: 1.35, 95% CI: 1.07 to 1.71; p = 0.012). PAPP-A also improved the net reclassification for CVD/MI (p = 0.003). There was no significant interaction with ranolazine.ConclusionsPAPP-A was independently associated with recurrent cardiovascular events in patients with NSTE-ACS. This finding supports PAPP-A as a candidate prognostic marker in patients with ACS and supports investigation of its therapeutic implications

Chaos, Fractals and Inflation

In order to draw out the essential behavior of the universe, investigations of early universe cosmology often reduce the complex system to a simple integrable system. Inflationary models are of this kind as they focus on simple scalar field scenarios with correspondingly simple dynamics. However, we can be assured that the universe is crowded with many interacting fields of which the inflaton is but one. As we describe, the nonlinear nature of these interactions can result in a complex, chaotic evolution of the universe. Here we illustrate how chaotic effects can arise even in basic models such as homogeneous, isotropic universes with two scalar fields. We find inflating universes which act as attractors in the space of initial conditions. These universes display chaotic transients in their early evolution. The chaotic character is reflected by the fractal border to the basin of attraction. The broader implications are likely to be felt in the process of reheating as well as in the nature of the cosmic background radiation.Comment: 16 pages, RevTeX. See published version for fig

The mixmaster universe: A chaotic Farey tale

When gravitational fields are at their strongest, the evolution of spacetime is thought to be highly erratic. Over the past decade debate has raged over whether this evolution can be classified as chaotic. The debate has centered on the homogeneous but anisotropic mixmaster universe. A definite resolution has been lacking as the techniques used to study the mixmaster dynamics yield observer dependent answers. Here we resolve the conflict by using observer independent, fractal methods. We prove the mixmaster universe is chaotic by exposing the fractal strange repellor that characterizes the dynamics. The repellor is laid bare in both the 6-dimensional minisuperspace of the full Einstein equations, and in a 2-dimensional discretisation of the dynamics. The chaos is encoded in a special set of numbers that form the irrational Farey tree. We quantify the chaos by calculating the strange repellor's Lyapunov dimension, topological entropy and multifractal dimensions. As all of these quantities are coordinate, or gauge independent, there is no longer any ambiguity--the mixmaster universe is indeed chaotic.Comment: 45 pages, RevTeX, 19 Figures included, submitted to PR

Chaos in the Einstein-Yang-Mills Equations

Yang-Mills color fields evolve chaotically in an anisotropically expanding universe. The chaotic behaviour differs from that found in anisotropic Mixmaster universes. The universe isotropizes at late times, approaching the mean expansion rate of a radiation-dominated universe. However, small chaotic oscillations of the shear and color stresses continue indefinitely. An invariant, coordinate-independent characterisation of the chaos is provided by means of fractal basin boundaries.Comment: 3 pages LaTeX + 3 pages of figure

Association of early imaging for back pain with clinical outcomes in older adults

IMPORTANCE: In contrast to the recommendations for younger adults, many guidelines allow for older adults with back pain to undergo imaging without waiting 4 to 6 weeks. However, early imaging may precipitate interventions that do not improve outcomes. OBJECTIVE: To compare function and pain at the 12-month follow-up visit among older adults who received early imaging with those who did not receive early imaging after a new primary care visit for back pain without radiculopathy. DESIGN, SETTING, AND PARTICIPANTS: Prospective cohort of 5239 patients 65 years or older with a new primary care visit for back pain (2011-2013) in 3 US health care systems. We matched controls 1:1 using propensity score matching of demographic and clinical characteristics, including diagnosis, pain severity, pain duration, functional status, and prior resource use. EXPOSURES: Diagnostic imaging (plain films, computed tomography [CT], magnetic resonance imaging [MRI]) of the lumbar or thoracic spine within 6 weeks of the index visit. PRIMARY OUTCOME: back or leg pain-related disability measured by the modified Roland-Morris Disability Questionnaire (score range, 0-24; higher scores indicate greater disability) 12 months after enrollment. RESULTS: Among the 5239 patients, 1174 had early radiographs and 349 had early MRI/CT. At 12 months, neither the early radiograph group nor the early MRI/CT group differed significantly from controls on the disability questionnaire. The mean score for patients who underwent early radiography was 8.54 vs 8.74 among the control group (difference, -0.10 [95% CI, -0.71 to 0.50]; mixed model, P = .36). The mean score for the early MRI/CT group was 9.81 vs 10.50 for the control group (difference,-0.51 [-1.62 to 0.60]; mixed model, P = .18). CONCLUSIONS AND RELEVANCE: Among older adults with a new primary care visit for back pain, early imaging was not associated with better 1-year outcomes. The value of early diagnostic imaging in older adults for back pain without radiculopathy is uncertain

Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression

Fibrosis compromises pancreatic ductal carcinoma (PDAC) treatment and contributes to patient mortality yet anti-stromal therapies are controversial. We found that human PDACs with impaired epithelial transforming growth factor β (TGF-β) signaling have elevated epithelial Stat3 activity and develop a stiffer, matricellular-enriched fibrosis associated with high epithelial tension and shorter patient survival. In several Kras-driven mouse models, both the loss of TGF-β signaling and elevated β1-integrin mechanosignaling engaged a positive feedback loop whereby Stat3 signaling promotes tumor progression by increasing matricellular fibrosis and tissue tension. In contrast, epithelial Stat3 ablation attenuated tumor progression by reducing the stromal stiffening and epithelial contractility induced by loss of TGF-β signaling. In PDAC patient biopsies, higher matricellular protein and activated Stat3 associated with SMAD4 mutation and shorter survival. The findings implicate epithelial tension and matricellular fibrosis in the aggressiveness of SMAD4 mutant pancreatic tumors, and highlight Stat3 and mechanics as key drivers of this phenotype