119 research outputs found
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Is antipsychotic medication stigmatizing for people with mental illness?
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THE NEW PARADIGM OF RECOVERY FROM SCHIZOPHRENIA: CULTURAL CONUNDRUMS OF IMPROVEMENT WITHOUT CURE
Medication treatment perceptions, concerns and expectations among depressed individuals with Type I Bipolar Disorder
BACKGROUND: Subjective experience of illness affects outcomes among populations with bipolar disorder (BD). This cross-sectional study combined qualitative and quantitative approaches to evaluate perceived treatment effects, concerns and expectations among 90 individuals with BD. METHODS: Adults with type I BD, mean age 36.6 years, 51% women, completed a semi-structured interview that was audio taped, transcribed, coded and analyzed along emergent themes. Quantitative scales measured depressive symptoms (Hamilton Depression Scale/HAMD), psychopathology (Clinical Global Impression/CGI), and insight and treatment attitudes (Insight and Treatment Attitudes Questionnaire/ITAQ). RESULTS: Individuals had moderate depression and psychopathology with good insight into need for treatment. Drug treatment was perceived as beneficial, by “stabilizing” or “balancing” mood (42%, N=38), decreasing anxiety/depressive symptoms (19%, N=17) and improving sleep (10%, N=9). While 39%, (N=35) of individuals denied medication concerns, nearly 29%, (N=26) feared possible long-term effects, particularly diabetes or liver/kidney damage. Media stories and advertisements contributed to medication fears. Hopes and expectations for treatment ranged from those that were symptom or functional status-based, such as desiring mood stabilization and elimination of specific symptoms (23%, N=21), to more global hopes such as “being normal” (20%, N=18) or “cured” (18%, N=16). LIMITATIONS: Limitations include relatively small sample, lack of a comparator, inclusion of only depressed individuals and those willing to discuss their illness experience. CONCLUSIONS: While individuals with BD appreciate the effects of medications, concerns regarding adverse effects and discrepancy between actual and hoped-for outcomes can be substantial. Subjective experience with medications using qualitative and quantitative methods should be explored in order to optimize treatment collaboration and outcomes
Evolution by Any Other Name: Antibiotic Resistance and Avoidance of the E-Word
The word "evolution" is rarely used in papers from medical journals describing antimicrobial resistance, which may directly impact public perception of the importance of evolutionary biology in our everyday lives
Three Saturn-mass planets transiting F-type stars revealed with TESS and HARPS
While the sample of confirmed exoplanets continues to increase, the
population of transiting exoplanets around early-type stars is still limited.
These planets allow us to investigate the planet properties and formation
pathways over a wide range of stellar masses and study the impact of high
irradiation on hot Jupiters orbiting such stars. We report the discovery of
TOI-615b, TOI-622b, and TOI-2641b, three Saturn-mass planets transiting main
sequence, F-type stars. The planets were identified by the Transiting Exoplanet
Survey Satellite (TESS) and confirmed with complementary ground-based and
radial velocity observations. TOI-615b is a highly irradiated (1277
) and bloated Saturn-mass planet (1.69
and 0.43) in a 4.66 day orbit transiting a 6850 K
star. TOI-622b has a radius of 0.82 and a mass of
0.30~ in a 6.40 day orbit. Despite its high
insolation flux (600 ), TOI-622b does not show any evidence
of radius inflation. TOI-2641b is a 0.37 planet in a
4.88 day orbit with a grazing transit (b = 1.04) that
results in a poorly constrained radius of 1.61.
Additionally, TOI-615b is considered attractive for atmospheric studies via
transmission spectroscopy with ground-based spectrographs and .
Future atmospheric and spin-orbit alignment observations are essential since
they can provide information on the atmospheric composition, formation and
migration of exoplanets across various stellar types.Comment: 16 pages, 17 figures, submitted to A&
A universal scaling relationship between body mass and proximal limb bone dimensions in quadrupedal terrestrial tetrapods
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