383 research outputs found

    High Power Solid State Retrofit Lamp Thermal Characterization and Modeling

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    Thermal and thermo-mechanical modeling and characterization of solid state lightening (SSL) retrofit LED lamp are presented in this paper. Paramount importance is to design SSL lamps for reliability, in which thermal and thermo-mechanical aspects are key points. The main goal is to get a precise 3D thermal lamp model for further thermal optimization. Simulations are performed with ANSYS and CoventorWare software tools to compere different simulation approaches. Simulated thermal distribution has been validated with thermal measurement on a commercial 8W LED lamp. Materials parametric study has been carried out to discover problematic parts for heat transfer from power LEDs to ambient and future solutions are proposed. The objectives are to predict the thermal management by simulation of LED lamp, get more understanding in the effect of lamp shape and used materials in order to design more effective LED lamps and predict light quality, life time and reliability

    Local recovery of cardiac calcium‐induced calcium release interrogated by ultra‐effective, two‐photon uncaging of calcium

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    KEY POINTS: In cardiac myocytes, subcellular local calcium release signals, calcium sparks, are recruited to form each cellular calcium transient and activate the contractile machinery. Abnormal timing of recovery of sparks after their termination may contribute to arrhythmias. We developed a method to interrogate recovery of calcium spark trigger probabilities and their amplitude over time using two‐photon photolysis of a new ultra‐effective caged calcium compound. The findings confirm the utility of the technique to define an elevated sensitivity of the calcium release mechanism in situ and to follow hastened recovery of spark trigger probabilities in a mouse model of an inherited cardiac arrhythmia, which was used for validation. Analogous methods are likely to be applicable to investigate other microscopic subcellular signalling systems in a variety of cell types. ABSTRACT: In cardiac myocytes Ca(2+)‐induced Ca(2+) release (CICR) from the sarcoplasmic reticulum (SR) through ryanodine receptors (RyRs) governs activation of contraction. Ca(2+) release occurs via subcellular Ca(2+) signalling events, Ca(2+) sparks. Local recovery of Ca(2+) release depends on both SR refilling and restoration of Ca(2+) sensitivity of the RyRs. We used two‐photon (2P) photolysis of the ultra‐effective caged Ca(2+) compound BIST‐2EGTA and laser‐scanning confocal Ca(2+) imaging to probe refractoriness of local Ca(2+) release in control conditions and in the presence of cAMP or low‐dose caffeine (to stimulate CICR) or cyclopiazonic acid (CPA; to slow SR refilling). Permeabilized cardiomyocytes were loaded with BIST‐2EGTA and rhod‐2. Pairs of short 2P photolytic pulses (1 ms, 810 nm) were applied with different intervals to test Ca(2+) release amplitude recovery and trigger probability for the second spark in a pair. Photolytic and biological events were distinguished by classification with a self‐learning support vector machine (SVM) algorithm. In permeabilized myocytes data recorded in the presence of CPA showed a lower probability of triggering a second spark compared to control or cAMP conditions. Cardiomyocytes from a mouse model harbouring the arrhythmogenic RyR(R420Q) mutation were used for further validation and revealed a higher Ca(2+) sensitivity of CICR. This new 2P approach provides composite information of Ca(2+) release amplitude and trigger probability recovery reflecting both SR refilling and restoration of CICR and RyR Ca(2+) sensitivity. It can be used to measure the kinetics of local CICR recovery, alterations of which may be related to premature heart beats and arrhythmias

    Strain Modulation of Graphene by Nanoscale Substrate Curvatures: A Molecular View

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    Spatially nonuniform strain is important for engineering the pseudomagnetic field and band structure of graphene. Despite the wide interest in strain engineering, there is still a lack of control on device-compatible strain patterns due to the limited understanding of the structure-strain relationship. Here, we study the effect of substrate corrugation and curvature on the strain profiles of graphene via combined experimental and theoretical studies of a model system: graphene on closely packed SiO2 nanospheres with different diameters (20-200 nm). Experimentally, via quantitative Raman analysis, we observe partial adhesion and wrinkle features and find that smaller nanospheres induce larger tensile strain in graphene, theoretically, molecular dynamics simulations confirm the same microscopic structure and size dependence of strain and reveal that a larger strain is caused by a stronger, inhomogeneous interaction force between smaller nanospheres and graphene. This molecular-level understanding of the strain mechanism is important for strain engineering of graphene and other two-dimensional materials.Comment: Nano Letters (2018

    Observation of the Dynamic Beta Effect at CESR with CLEO

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    Using the silicon strip detector of the CLEO experiment operating at the Cornell Electron-positron Storage Ring (CESR), we have observed that the horizontal size of the luminous region decreases in the presence of the beam-beam interaction from what is expected without the beam-beam interaction. The dependence on the bunch current agrees with the prediction of the dynamic beta effect. This is the first direct observation of the effect.Comment: 9 page uuencoded postscript file, postscritp file also available through http://w4.lns.cornell.edu/public/CLNS, submitted to Phys. Rev.

    Flavor-Specific Inclusive B Decays to Charm

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    We have measured the branching fractions for B -> D_bar X, B -> D X, and B -> D_bar X \ell^+ \nu, where ``B'' is an average over B^0 and B^+, ``D'' is a sum over D^0 and D^+, and``D_bar'' is a sum over D^0_bar and D^-. From these results and some previously measured branching fractions, we obtain Br(b -> c c_bar s) = (21.9 ±\pm 3.7)%, Br(b -> s g) K^- \pi^+) = (3.69 ±\pm 0.20)%. Implications for the ``B semileptonic decay problem'' (measured branching fraction being below theoretical expectations) are discussed. The increase in the value of Br(b -> c c_bar s) due to B>DXB -> D X eliminates 40% of the discrepancy.Comment: 12 page postscript file, postscript file also available through http://w4.lns.cornell.edu/public/CLN

    First Observation of Υ(1S)γππ\Upsilon(1S)\to \gamma\pi\pi

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    We report on a study of exclusive radiative decays of the Upsilon(1S) resonance collected with the CLEO-II detector operating at CESR. We present the first observation of the radiative decays Upsilon(1S)->gamma pi+pi- and Upsilon(1S)->gamma pi0pi0. For the dipion mass regime m(pipi)>1.0 GeV, we obtain Br(Upsilon(1S)->gamma pi+pi-=(6.3+/-1.2+/-1.3) x 10^(-5), and Br(Upsilon(1S)->gamma pi0pi0=(1.7+/-0.6+/-0.3) x 10^(-5). The observed gamma pipi events are consistent with the hypothesis Upsilon(1S)->gamma f2(1270).Comment: 9 pages, postscript file also available through http://w4.lns.cornell.edu/public/CLN

    Further Search for the Two-Photon Production of the Glueball Candidate fJ(2220)f_{J}(2220)

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    The CLEOII detector at the Cornell e+ e- storage ring CESR has been used to search for the two-photon production of the fJ(2220)f_J(2220) decaying into pi+ pi-. No evidence for a signal is found in data corresponding to an integrated luminosity of 4.77/fb and a 95% CL upper limit on ΓtwophotonBRpi+pi\Gamma_{two-photon} * BR{pi+ pi-} of 2.5 eV is set. If this result is combined with the BES Collaboration's measurement of fJ(2220)>pi+pif_J(2220) -> pi+ pi- in radiative J/ψJ/\psi decay, a 95% CL lower limit on the stickiness of the fJ(2220)f_J(2220) of 73 is obtained. If the recent CLEO result for \Gamma_{two-photon} * BR{\K_S K_S} is combined with the present result, the stickiness of the fJ(2220)f_J(2220) is found to be larger than 102 at the 95% CL. These results for the stickiness (the ratio of the probabilities for two-gluon coupling and two-photon coupling) provide further support for a substantial neutral parton content in the fJ(2220)f_J(2220).Comment: 8 pages, postscript file also available through http://w4.lns.cornell.edu/public/CLN

    Observation of the Isospin-Violating Decay Ds+Ds+π0D_s^{*+}\to D_s^+\pi^0

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    Using data collected with the CLEO~II detector, we have observed the isospin-violating decay Ds+Ds+π0D_s^{*+}\to D_s^+\pi^0. The decay rate for this mode, relative to the dominant radiative decay, is found to be Γ(Ds+Ds+π0)/Γ(Ds+Ds+γ)=0.0620.018+0.020±0.022\Gamma(D_s^{*+}\to D_s^+\pi^0)/\Gamma(D_s^{*+}\to D_s^+\gamma)= 0.062^{+0.020}_{-0.018}\pm0.022.Comment: 8 page uuencoded postscript file, also available through http://w4.lns.cornell.edu/public/CLN

    Measurement of Br(D0Kπ+)Br(D^{0}\to K^{-}\pi^{+}) using Partila Reconstruction of BˉD+Xνˉ\bar{B}\to D^{*+}X\ell^{-}\bar{\nu}

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    We present a measurement of the absolute branching fraction for D0>Kpi+D^0 -> K^- pi^+ using the reconstruction of the decay chain Bbar>D+XlnubarBbar -> D^{*+} X l^- nubar , D+>D0pi+D^{*+} -> D^0 pi^+ where only the lepton and the low-momentum pion from the D+D^{*+} are detected. With data collected by the CLEO II detector at the Cornell Electron Storage Ring, we have determined Br(D0>Kpi+)=[3.81+0.15(stat.)+0.16(syst.)]Br(D^0 -> K^- pi^+)= [3.81 +- 0.15(stat.) +- 0.16(syst.)]%.Comment: 10 page postscript file, postscript file also available through http://w4.lns.cornell.edu/public/CLN

    Update of the Search for the Neutrinoless Decay τμγ\tau\to \mu\gamma

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    We present an update of the search for the lepton family number violating decay τμγ\tau \to \mu\gamma using a complete CLEO II data sample of 12.6 million τ+τ\tau^+\tau^- pairs. No evidence of a signal has been found and the corresponding upper limit is \BR(\tau \to \mu\gamma) < 1.0 \times 10^{-6} at 90% CL, significantly smaller than previous limits. All quoted results are preliminary.Comment: 9 pages postscript, also available through http://w4.lns.cornell.edu/public/CLN
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