Chitinase family GH18: evolutionary insights from the genomic history of a diverse protein family-3

<p><b>Copyright information:</b></p><p>Taken from "Chitinase family GH18: evolutionary insights from the genomic history of a diverse protein family"</p><p>http://www.biomedcentral.com/1471-2148/7/96</p><p>BMC Evolutionary Biology 2007;7():96-96.</p><p>Published online 26 Jun 2007</p><p>PMCID:PMC1945033.</p><p></p> the legend for Figure 1. JGI model protein ID numbers are used for proteins, accession numbers for the proteins, and gene symbols (or protein symbols when gene symbols are not available) for mammalian proteins. A black bracket indicates the chitinases/chitolectins, a dark blue bracket the stabilin-1 interacting chitolectins, and a dark gray bracket the chitobiases

Chitinase family GH18: evolutionary insights from the genomic history of a diverse protein family-2

<p><b>Copyright information:</b></p><p>Taken from "Chitinase family GH18: evolutionary insights from the genomic history of a diverse protein family"</p><p>http://www.biomedcentral.com/1471-2148/7/96</p><p>BMC Evolutionary Biology 2007;7():96-96.</p><p>Published online 26 Jun 2007</p><p>PMCID:PMC1945033.</p><p></p>he legend for Figure 1. Binomen abbreviations are used for species, gene symbols for human proteins, and accession numbers for and proteins. A black bracket at the right indicates the clade encompassing all the human chitinases/chitolectins, two domains from a single protein of , and a single protein of ; a dark gray bracket indicates the clade encompassing the imaginal disc growth factors (chitolectins); and a dark blue bracket the stabilin-1 interacting chitolectin group. Scale, bootstrapping and rooting are as described for Figure 1. Bootstrap values ≥ 50% are shown

Chitinase family GH18: evolutionary insights from the genomic history of a diverse protein family-4

<p><b>Copyright information:</b></p><p>Taken from "Chitinase family GH18: evolutionary insights from the genomic history of a diverse protein family"</p><p>http://www.biomedcentral.com/1471-2148/7/96</p><p>BMC Evolutionary Biology 2007;7():96-96.</p><p>Published online 26 Jun 2007</p><p>PMCID:PMC1945033.</p><p></p> boxed in red. Arrows point to the locations of the human family GH18 genes (symbols underlined to distinguish them from MHC related genes) and representative genes from the MHC paralogous region. The choice of genes is based on a recent comparative analysis of the MHC [48]. The MHC paralog symbols are: LYPLA2, lysophospholipase II (1p36.12-p35.1); DDAH1, dimethylarginine dimethylaminohydrolase 1 (1p22); BRDT, bromodomain, testis-specific (1p22.1); COL11A1, collagen, type XI alpha 1 (1p21); VAV3, vav 3 oncogene (1p13.3), DDR2, discoidin domain receptor family, member 2 (1q12-q23); RXRG, retinoid X receptor, gamma, 1q22-q23); TNFS4, tumor necrosis factor (ligand) superfamily, member 4 (1q25); PTGS2, prostaglandin-endoperoxide synthase 2 (1q25.2-q25.3); and B3GALT2, UDP-Gal:beta GlcNAc beta 1,3-galactosyltransferase, polypeptide 2 (1q31)

Chitinase family GH18: evolutionary insights from the genomic history of a diverse protein family-5

<p><b>Copyright information:</b></p><p>Taken from "Chitinase family GH18: evolutionary insights from the genomic history of a diverse protein family"</p><p>http://www.biomedcentral.com/1471-2148/7/96</p><p>BMC Evolutionary Biology 2007;7():96-96.</p><p>Published online 26 Jun 2007</p><p>PMCID:PMC1945033.</p><p></p> two MHC paralogous regions (chr 1). Red asterisks indicate the loci for the human chitinase/chitolectin genes on chr1 (p13.3-p13.2) and chr1 (q32.1). The labeled horizontal arrows below the two ideograms designate the regions and orientations of human chromosomes 1 and 6 that correspondingly align with chromosome 26 (black); scaffold 41 (gray), and chromosome 2 (diagonal-pattern)