Abolishing user fees for children and pregnant women trebled uptake of malaria-related interventions in Kangaba, Mali.

Malaria is the most common cause of morbidity and mortality in children under 5 in Mali. Health centres provide primary care, including malaria treatment, under a system of cost recovery. In 2005, Médecins sans Frontieres (MSF) started supporting health centres in Kangaba with the provision of rapid malaria diagnostic tests and artemisinin-based combination therapy. Initially MSF subsidized malaria tests and drugs to reduce the overall cost for patients. In a second phase, MSF abolished fees for all children under 5 irrespective of their illness and for pregnant women with fever. This second phase was associated with a trebling of both primary health care utilization and malaria treatment coverage for these groups. MSF's experience in Mali suggests that removing user fees for vulnerable groups significantly improves utilization and coverage of essential health services, including for malaria interventions. This effect is far more marked than simply subsidizing or providing malaria drugs and diagnostic tests free of charge. Following the free care strategy, utilization of services increased significantly and under-5 mortality was reduced. Fee removal also allowed for more efficient use of existing resources, reducing average cost per patient treated. These results are particularly relevant for the context of Mali and other countries with ambitious malaria treatment coverage objectives, in accordance with the United Nations Millennium Development Goals. This article questions the effectiveness of the current national policy, and the effectiveness of reducing the cost of drugs only (i.e. partial subsidies) or providing malaria tests and drugs free for under-5s, without abolishing other related fees. National and international budgets, in particular those that target health systems strengthening, could be used to complement existing subsidies and be directed towards effective abolition of user fees. This would contribute to increasing the impact of interventions on population health and, in turn, the effectiveness of aid

Backgrounding calves part 1 : assessing the opportunity (1993)

Backgrounding is the growing of steers and heifers from weaning until they enter the feedlot for finishing. It is suited to farmers who do not want to maintain a cow herd, do not want to finish cattle, but do want to put added weight on calves after weaning

Backgrounding calves part 2 : herd health and feeding (1993)

Backgrounding calves, or taking weaned calves at about 450 pounds and feeding them up to 750 pounds or so, is becoming more popular among cattle producers. It can be a profit maker for the producer who wants an alternative to the cow/calf business, wants to use excess forage or other roughages, has extra time during parts of the year, or wants to add flexibility to his current cattle operation

Backgrounding calves. Part 2. Herd health and feeding

"In Part 1 of this Agricultural Guide (number 2095) we discussed basic backgrounding strategies and compared profitability with other cattle enterprises. In this section, we will focus on herd health requirements and feeding for successful backgrounding. There are many animal health problems to consider, especially if you will be purchasing most or all of the calves to be backgrounded."--First page.Homer B. Sewell (Department of Animal Sciences), Victor E. Jacobs (Department of Agricultural Economics), and James R. Gerrish (Department of Agronomy)New 12/88/5

Backgrounding calves

"Backgrounding is the growing of steers and heifers from weaning until they enter the feedlot for finishing. It is suited to farmers who do not want to maintain a cow herd, do not want to finish cattle but do want to put added weight on calves after weaning."--First page.Homer B. Sewell (Department of Animal Sciences), Victor E. Jacobs (Department of Agricultural Economics), James R. Gerrish (Department of Agronomy)New 12/88/5

Women can bear a bigger burden: ante- and post-mortem evidence for reserve in the face of tau.

In this study, we aimed to assess whether women are able to withstand more tau before exhibiting verbal memory impairment. Using data from 121 amyloid-β-positive Alzheimer's Disease Neuroimaging Initiative participants, we fit a linear model with Rey Auditory Verbal Learning Test score as the response variable and tau-PET standard uptake value ratio as the predictor and took the residuals as an estimate of verbal memory reserve for each subject. Women demonstrated higher reserve (i.e. residuals), whether the Learning (t = 2.78, P = 0.006) or Delay (t = 2.14, P = 0.03) score from the Rey Auditory Verbal Learning Test was used as a measure of verbal memory ability. To validate these findings, we examined 662 National Alzheimer's Coordinating Center participants with a C2/C3 score (Consortium to Establish a Registry for Alzheimer's Disease) at autopsy. We stratified our National Alzheimer's Coordinating Center sample into Braak 1/2, Braak 3/4 and Braak 5/6 subgroups. Within each subgroup, we compared Logical Memory scores between men and women. Men had worse verbal memory scores within the Braak 1/2 (Logical Memory Immediate: β = -5.960 ± 1.517, P < 0.001, Logical Memory Delay: β = -5.703 ± 1.677, P = 0.002) and Braak 3/4 (Logical Memory Immediate: β = -2.900 ± 0.938, P = 0.002, Logical Memory Delay: β = -2.672 ± 0.955, P = 0.006) subgroups. There were no sex differences in Logical Memory performance within the Braak 5/6 subgroup (Logical Memory Immediate: β = -0.314 ± 0.328, P = 0.34, Logical Memory Delay: β = -0.195 ± 0.287, P = 0.50). Taken together, our results point to a sex-related verbal memory reserve