Tool and process for miniature explosive joining of tubes

A tool and process to be used in the explosive joining of tubes is disclosed. The tool consists of an initiator, a tool form, and a ribbon explosive. The assembled tool is a compact, storable, and safe device suitable for explosive joining of small, lightweight tubes down to 0.20 inch in diameter. The invention is inserted into either another tube or a tube plate. A shim or standoff between the two surfaces to be welded is necessary. Initiation of the explosive inside the tube results in a high velocity, angular collision between the mating surfaces. This collision creates surface melts and collision bonding wherein electron-sharing linkups are formed

Ignitability test method and apparatus

An apparatus for testing ignitability of an initiator includes a body having a central cavity, an initiator holder for holding the initiator over the central cavity of the body, an ignition material holder disposed in the central cavity of the body and having a cavity facing the initiator holder which receives a measured quantity of ignition material to be ignited by the initiator. It contains a chamber in communication with the cavity of the ignition material and the central cavity of the body, and a measuring system for analyzing pressure characteristics generated by ignition of the ignition material by the initiator. The measuring system includes at least one transducer coupled with an oscillograph for recording pressure traces generated by ignition

Ignitability test method and apparatus

An apparatus for testing ignitability of an initiator includes a body with a central cavity, initiator holder for holding the initiator over the central cavity of the body, an ignition material holder disposed in the central cavity of the body and a cavity facing the initiator holder which receives a measured quantity of ignition material to be ignited by the initiator and a chamber in communication with the cavity of the ignition material holder and the central cavity of the body. A measuring system for analyzing pressure characteristics is generated by ignition material by the initiator. The measuring system includes at least one transducer coupled to an oscillograph for recording pressure traces generated by ignition

A Monodentate 1,3-Diphenyl-2-triazeno Terpyridineplatinum(II) Complex

The compound (l,3-diphenyl-2-triazeno )(2,2',2"- terpyridine)platinum(II) perchlorate dimethylformamide solvate (1) is formed by reaction of dpt (dptH = 1,3-diphenyltriazene) and [Pt(tpy)Cl]Cl (tpy = terpyridine) in the presence of excess base (NEt3). There are two independent cations in the asymmetric unit. The platinum centers have a monodentate triazeno ligand with the remaining coordination sites occupied by the terpyridine group. The crystal packing is dominated by π-π stacking interactions, and metal-metal interactions are conspicuously absent

Effects of Exercise on Glycemic Response after Consumption of Monster Energy

Energy drinks have been anecdotally associated with deleterious cardiovascular health outcomes. These drinks contain ingredients, including but not limited to caffeine, which could affect glycemic response to the carbohydrate ingredients in the drink. Exercise alters insulin sensitivity and could be a factor related to the response to acute energy drink response. The aim of this study was to determine if acute exercise would alter the glycemic and physiological response to the consumption of Monster Energy ©. Following an overnight fast, human subjects (age 19.11±1.39; 30 female; 5 male) were randomized to exercise on a stationary bike at 33% of their predicted VO2 max for 10 minutes with a five minute sitting rest after, or sitting (control) for five minutes prior to ingestion of Monster Energy. Blood glucose, heart rate, and blood pressure were measured 0-, 30-, 60- , and 90-minutes postprandially. Data is represented as LSM ± SE with significance analyzed using a t-test, or multiple comparison test. Significance is assumed when P\u3c 0.05. Blood glucose (mg/dL) for control at 0-, 30-, 60-, and 90-minutes 91.58±1.2, 133.7±4.29, 96.3±4.17, and 82.4±1.82 mg/dL, respectively. For those receiving bike exercise prior to ingestion blood glucose was 92.2±1.2, 126.6±3.79, 92.5±2.27, 84.0±1.77 mg/dL. There were no significant blood glucose differences observed between groups across time, within group significance in both groups was observed between 0 and 30, 30 and 60, and 60 and 90, for control only. Heart rate for control at 0-, 30-, 60-, and 90-minutes was 78.0±3.06, 78.2±2.55, 78.6±2.6, and 74.4±1.85 respectively. For those receiving bike exercise prior to ingestion heart rate was 88.7±3.71, 85.5±2.69, 83.1±2.35, and 80.3±2.89. There were no significant heart rate differences observed between groups across time, within group significance in both groups was observed between 0 and 30, 30 and 60, and 60 and 90, for control only. Blood pressure for control at 0-, 30-, 60-, and 90-minutes was 86.8±2.05, 89.2±2.05, 89.2±2.5, and 87.6±2.6. For those receiving bike exercise prior to ingestion blood pressure was 90.6±3.07, 88.98±2.3, 88.2±1.97, and 86.98±2.08. There were no significant blood pressure differences observed between groups across time, within group significance in both groups was observed between 0 and 30, 30 and 60, and 60 and 90, for control only. In conclusion exercise probably does not alter the glycemic and physiological response to energy drinks.https://openriver.winona.edu/urc2019/1092/thumbnail.jp

Development of Fuses for Protection of Geiger-Mode Avalanche Photodiode Arrays

Current-limiting fuses composed of Ti/Al/Ni were developed for use in Geiger-mode avalanche photodiode arrays for each individual pixel in the array. The fuses were designed to burn out at ∼4.5 × 10[superscript −3] A and maintain post-burnout leakage currents less than 10[superscript −7] A at 70 V sustained for several minutes. Experimental fuse data are presented and successful incorporation of the fuses into a 256 × 64 pixel InP-based Geiger-mode avalanche photodiode array is reported

Histone Hypervariants H2A.Z.1 and H2A.Z.2 Play Independent and Context-Specific Roles in Neuronal Activity-Induced Transcription of Arc/Arg3.1 and Other Immediate Early Genes.

The histone variant H2A.Z is an essential and conserved regulator of eukaryotic gene transcription. However, the exact role of this histone in the transcriptional process remains perplexing. In vertebrates, H2A.Z has two hypervariants, H2A.Z.1 and H2A.Z.2, that have almost identical sequences except for three amino acid residues. Due to such similarity, functional specificity of these hypervariants in neurobiological processes, if any, remain largely unknown. In this study with dissociated rat cortical neurons, we asked if H2A.Z hypervariants have distinct functions in regulating basal and activity-induced gene transcription. Hypervariant-specific RNAi and microarray analyses revealed that H2A.Z.1 and H2A.Z.2 regulate basal expression of largely nonoverlapping gene sets, including genes that code for several synaptic proteins. In response to neuronal activity, rapid transcription of our model gene Arc is impaired by depletion of H2A.Z.2, but not H2A.Z.1. This impairment is partially rescued by codepletion of the H2A.Z chaperone, ANP32E. In contrast, under a different context (after 48 h of tetrodotoxin, TTX), rapid transcription of Arc is impaired by depletion of either hypervariant. Such context-dependent roles of H2A.Z hypervariants, as revealed by our multiplexed gene expression assays, are also evident with several other immediate early genes, where regulatory roles of these hypervariants vary from gene to gene under different conditions. Together, our data suggest that H2A.Z hypervariants have context-specific roles that complement each other to mediate activity-induced neuronal gene transcription

Percutaneous reduction and fixation of an intra-articular calcaneal fracture using an inflatable bone tamp: description of a novel and safe technique

Calcaneal fractures are common injuries involving the hind foot and often a source of significant long-term morbidity. Treatment options have changed throughout the ages from periods of preferred nonoperative management to closed reduction with a mallet, and more recently, open reduction and anatomic internal fixation. The current treatment of choice; however, is often debated, as open management of these fractures carries many risks to include wound breakdown and infection. A less invasive form of surgical management through small incisions, while maintaining the ability to obtain joint congruency, anatomic alignment, and restore calcaneal height and width would be ideal. We propose a novel form of fracture reduction using an inflatable bone tamp and percutaneous fracture fixation. Preoperative planning and experienced fluoroscopy is crucial to successful management using this method. Although we achieved successful radiographic outcome in this case, long-term functional outcome of this technique are yet to be published

Clinical Hearing Aid Dispensing: A Five Year Review

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