12,519 research outputs found

    Cyber-pseudepigraphy: A New Challenge for Higher Education Policy and Management

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    There is no lack of critical literature dealing with cyber-plagiarism and the implications for assessment in higher education. The practice of the selling of academic papers through the Internet is generally included under the category of plagiarism, although it is suggested that this ought to be considered under the separate category of cyber-pseudepigraphy. Pseudepigraphy is defined in this essay as the deliberate ascription of false authorship to a piece of writing, and cyber-pseudepigraphy is defined as using the Internet to have another person write an academic essay or paper, without this authorship being acknowledged. It is suggested that cyber-pseudepigraphy has widespread implications, and five critical issues are discussed. The essay finally raises the prospect of a return to some form of unseen examination as a method of student assessment as a way of dealing with this problem

    Information technology for detecting medication errors and adverse drug events

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    It is estimated that over three-quarters of a million people are injured or die in hospitals ‎each year from adverse drug events (ADE’s). The majority of medical errors result form ‎poorly designed healthcare systems rather than from negligence on the part of healthcare ‎providers. In general, healthcare systems rely on voluntary reporting, which seriously ‎underestimates the number of medication errors and ADE’s by as much as 90%. This ‎paper reviews the causes and impact of medication errors and ADE\u27s. It also reports ‎studies that have used information technology (IT) to detect and prevent medication ‎errors and ADE’s. Significant reduction of medication errors and ADE’s requires ‎systemic implementation of IT, improvements in the reporting of errors, and integration ‎of the components of the healthcare systems’ information systems. At the present time, ‎most healthcare systems should be able to use IT to detect and prevent ADE’s.

    Performance of a building integrated photovoltaic/thermal (BIPVT) solar collector

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    The idea of combining photovoltaic and solar thermal collectors (PVT collectors) to provide electrical and heat energy is an area that has, until recently, received only limited attention. Although PVTs are not as prevalent as solar thermal systems, the integration of photovoltaic and solar thermal collectors into the walls or roofing structure of a building could provide greater opportunity for the use of renewable solar energy technologies. In this study, the design of a novel building integrated photovoltaic/thermal (BIPVT) solar collector was theoretically analysed through the use of a modified Hottel–Whillier model and was validated with experimental data from testing on a prototype BIPVT collector. The results showed that key design parameters such as the fin efficiency, the thermal conductivity between the PV cells and their supporting structure, and the lamination method had a significant influence on both the electrical and thermal efficiency of the BIPVT. Furthermore, it was shown that the BIPVT could be made of lower cost materials, such as pre-coated colour steel, without significant decreases in efficiency. Finally, it was shown that by integrating the BIPVT into the building rather than onto the building could result in a lower cost system. This was illustrated by the finding that insulating the rear of the BIPVT may be unnecessary when it is integrated into a roof above an enclosed air filled attic, as this air space acts as a passive insulating barrier

    Can We Save the Traditional Family Farm?

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    What is a traditional family farm? Is it a family of four living on a farm and supplying all of the labor, capital and management or is it a family corporation with four families supplying all of the capital and management? These types of questions continue to arise in policy debates, as they have for many years. While subject to heated debate and the core of many people’s positions on farm programs the answer is more sociological as it is becoming less and less economically relevant. Whether these types of farms or any other farm sizes should survive is not a question that can be answered by a policy analyst. The job of an analyst is to determine if and under what conditions family farms can survive. To this end, this paper reviews the various definitions of family farms and draws inferences as to the economic and financial survival of these different size farms using the results generated from simulating representative farms.Agricultural and Food Policy,

    The Bipartite Structure of the tRNA m\u3csup\u3e1\u3c/sup\u3eA58 Methyltransferase from \u3cem\u3eS. cerevisiae\u3c/em\u3e is Conserved in Humans

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    Among all types of RNA, tRNA is unique given that it possesses the largest assortment and abundance of modified nucleosides. The methylation at N1 of adenosine 58 is a conserved modification, occurring in bacterial, archaeal, and eukaryotic tRNAs. In the yeast Saccharomyces cerevisiae, the tRNA 1-methyladenosine 58 (m1A58) methyltransferase (Mtase) is a two-subunit enzyme encoded by the essential genes TRM6 (GCD10) and TRM61 (GCD14). While the significance of many tRNA modifications is poorly understood, methylation of A58 is known to be critical for maintaining the stability of initiator tRNAMet in yeast. Furthermore, all retroviruses utilize m1A58-containing tRNAs to prime reverse transcription, and it has been shown that the presence of m1A58 in human tRNA3 Lys is needed for accurate termination of plus-strand strong-stop DNA synthesis during HIV-1 replication. In this study we have identified the human homologs of the yeast m1A Mtase through amino acid sequence identity and complementation of trm6 and trm61 mutant phenotypes. When coexpressed in yeast, human Trm6p and Trm61p restored the formation of m1A in tRNA, modifying both yeast initiator tRNAMet and human tRNA3 Lys. Stable hTrm6p/hTrm61p complexes purified from yeast maintained tRNA m1A Mtase activity in vitro. The human m1A Mtase complex also exhibited substrate specificity—modifying wild-type yeast tRNAi Met but not an A58U mutant. Therefore, the human tRNA m1A Mtase shares both functional and structural homology with the yeast tRNA m1A Mtase, possessing similar enzymatic activity as well as a conserved binary composition

    Analyzing Repeated Measures Marginal Models on Sample Surveys with Resampling Methods

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    Packaged statistical software for analyzing categorical, repeated measures marginal models on sample survey data with binary covariates does not appear to be available. Consequently, this report describes a customized SAS program which accomplishes such an analysis on survey data with jackknifed replicate weights for which the primary sampling unit information has been suppressed for respondent confidentiality. First, the program employs the Macro Language and the Output Delivery System (ODS) to estimate the means and covariances of indicator variables for the response variables, taking the design into account. Then, it uses PROC CATMOD and ODS, ignoring the survey design, to obtain the design matrix and hypothesis test specifications. Finally, it enters these results into another run of CATMOD, which performs automated direct input of the survey design specifications and accomplishes the appropriate analysis. This customized SAS program can be employed, with minor editing, to analyze general categorical, repeated measures marginal models on sample surveys with replicate weights. Finally, the results of our analysis accounting for the survey design are compared to the results of two alternate analyses of the same data. This comparison confirms that such alternate analyses, which do not properly account for the design, do not produce useful results.

    Post-Freedom to Farm Shifts in Regional Production Patterns

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    The FAIR Act of 1996, also known as the Freedom to Farm Act (ACT) dismantled many of the agriculture policy tools in use for the last 25 years. Gone were target prices, deficiency payments, and set asides. In their place were expanded marketing loan programs to effectively include wheat and feed grains and oilseeds in addition to cotton and rice. Full planting flexibility has been popular with farmers who are no longer constrained by base acres. Grain merchants and other volume oriented agribusinesses praise the elimination of set asides. The sharp decline in farm prices for all major program commodities since 1996 has left most farmers questioning the income safety net provisions of the FAIR Act. The flexibility and marketing loan provisions continue to be praised. Farm program changes in the 1996 farm bill rendered methods of crop supply response estimation based on econometric models, using historic data, difficult at best. Yet it can, and has been, hypothesized that the Act resulted in major shifts in regional crop production patterns. This paper draws inferences from changes in acres planted among crops for representative farms in the Texas A&M Agricultural and Food Policy Center’s (AFPC) farm data base. AFPC has maintained longitudinal data for more than three dozen representative crop farms across states, regions, farm size, and type of farm since 1990. The farms were updated in 1999 as to their crop mix changes following the ACT and the crop mix changes observed in the updates are summarized here. United States aggregate production shifts are identified from NASS data. Implications for future potential acreage changes are identified. The commodity focus includes feedgrains, soybeans, wheat, cotton, and rice.Agricultural and Food Policy,

    Support for the Harvard University Water Vapor and Total Water Instruments for the 2004 NASA WB57 Middle Latitude Cirrus Experiment

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    In order to improve our understanding of the role clouds play in the climate system, NASA is investing considerable effort in characterizing clouds with instruments ranging from passive remote sensors on board the EOS platforms, to the forthcoming active remote sensors on Cloudsat and Calipso. These missions, when taken together, have the capacity to advance our understanding of the coupling between various components of the hydrologic cycle and the atmospheric circulation, and hold the additional potential of leading to significant improvements in the characterization of cloud feedbacks in global models. This is especially true considering that several of these platforms will be flown in an identical orbit within several minutes of one another-a constellation of satellites known as the A-Train. The algorithms that are being implemented and developed to convert these new data streams from radiance and reflectivity measurements into geophysical parameters invariably rely on some set of simplifymg assumptions and empirical constants. Uncertainties in these relationships lead to poorly understood random and systematic errors in the retrieved properties. This lack of understanding introduces ambiguity in interpreting the data and in using the global data sets for their intended purposes. In light of this, a series of flights with the W57F was proposed to address certain specific issues related to the basic properties of mid latitude cirrus clouds: the NASA WE357 Middle Latitude Cirrus Experiment ("MidCiX"). The science questions addressed are: 1) Can cloud property retrieval algorithms developed for A-Train active and passive remote sensing measurements accurately characterize the microphysical properties of synoptic and convectively generated cirrus cloud systems? 2) What are the relationships between the cirrus particle mass, projected area, and particle size spectrum in various genre of cirrus clouds? 3) Does the present compliment of state of the art in situ cloud probes provide the level of precision and accuracy needed to develop and validate algorithms and to contribute to our understanding of the characteristics and microphysical processes operating in cirrus clouds

    The 1988 Arctic Survey, Diurnal Study (Sunrise and Sunset) and Peak Altitude (22 km) Flights for the In Situ Detection of ClO and BrO from the NASA ER-2 Aircraft

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    Two critical areas of research were addressed successfully by this research. The first involves NASA ER-2 airborne observations of ClO and BrO radical destruction of ozone within the arctic vortex. The second involves the analysis of diurnal variations in ClO, to test the production and loss rates of ClO that constitutes the test for coupling reactions between the chlorine and nitrogen systems. We discuss results from this research in order

    Southern Hemisphere In Situ Observations of OH, HO2, CIO and BrO from the ER-2 Aircraft for the 1994 ASHOE Mission

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    A summary of the first order scientific conclusions that emerged from the research done under this grant are as follows: (1) For the first time, the concentration of the key hydrogen and halogen radicals OH, H02, ClO and BrO were determined on a global scale extending from the arctic circle to the antarctic circle, over the altitude domain of the ER-2. That domain extends from 15-20 km altitude, covering a critical part of the lower stratosphere; (2) Simultaneous, in situ measurements of the concentrations of OH, H02, ClO, BrO, NO and NO2 demonstrate the predominance of odd-hydrogen and halogen free radical catalysis in determining the rate of removal of ozone in the lower stratosphere over the complete ASHOE mission. This extends to the global scale the "first look" data obtained during the NASA Stratospheric Photochemistry and Dynamics Experiment (SPADE), executed out of Ames Research Center in June 1993. This represents a major rearrangement of our understanding with respect to the hierarchy of dominant catalytic cycles controlling ozone loss in the lower stratosphere. For the past twenty years, it has been assumed that nitrogen radicals dominate the destruction rate of ozone in the lower stratosphere; (3) Throughout the altitude and latitude range covered by ASHOE, it was determined that a single catalytic cycle, HO2 + O3 yields OH + 2O2, accounted for one half of the total O3 removal in this region of the atmosphere. Halogen radical catalytic cycles were found to account for one third of the ozone loss, and nitrogen radicals were found to account for 20% of the loss; (4) Simultaneous observations of the full complement of radicals, tracers, ozone, and water vapor during ASHOE demonstrated quantitatively the coupling that exists between the rate limiting radicals and other reactive species in the photochemical reaction network. Specifically, the concentrations of ClO and HO2 are inversely correlated with the concentration of NOx. This carries the implication that the NOx effluent from the proposed High Speed Civil Transport may be less destructive to stratospheric ozone than had previously been thought. ASHOE brought this conclusion forward for the first time on a global basis; and (5) The density of BrO was measured on a global scale during ASHOE in the lower stratosphere. It was found that bromine is responsible for 55-65% of the local rate of catalytic destruction of ozone by reactions involving bromine and chlorine. Normalizing calculated loss rates to total available inorganic bromine and chlorine explicitly demonstrates that bromine is 60-80 times more efficient than chlorine in removing ozone in the lower stratosphere. An inferred value of total inorganic bromine is in excellent agreement with measurements of their source species, organic bromine compounds in the troposphere
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