Prevalence, incidence and etiology of hyponatremia in elderly patients with fragility fractures

Peer reviewedPublisher PD

Prognosis of hyponatremia in elderly patients with fragility fractures

Funding This work is supported by an NHS Research Scotland (NRS) Career Research Fellowship to Dr Soiza.Peer reviewedPublisher PD

Electrochemical Detection of Nanoscale Phase Separation in Binary Self-Assembled Monolayers

Developing methods to probe the nature and structure of nanoscale environments continues to be a challenge in nanoscience. We report a cyclic voltammetry investigation of internal, hydrogen-bond driven phase separation of amide-containing thiols and alkane thiols. Amide-containing thiols with a terminal ferrocene carboxylate functional group were investigated in two binary monolayers, one homogeneously mixed and the other phase separated. The electrochemical response of the ferrocene probe was used to monitor adsorbate coverage, environment and phase separation within each of these monolayers. The results demonstrate that the behavior of ferrocene containing monolayers can be used to probe nanoscale organization

Molecular gut-content analysis reveals high frequency of \u3ci\u3eHelicoverpa zea\u3c/i\u3e (Lepidoptera: Noctuidae) consumption by \u3ci\u3eOrius insidiosus\u3c/i\u3e (Hemiptera: Anthocoridae) in sweet corn

Management of corn earworm Helicoverpa zea in sweet corn grown for processing can be challenging due to the lack of effective transgenic and chemical control options. However, biological control by generalist predators can provide a significant impact on pests in this cropping system. One of the most ubiquitous predators of H. zea and other lepidopterans is the insidious flower bug, Orius insidiosus. This small hemipteran has been observed as an important mortality agent of H. zea in several cropping systems, but the strength of the trophic connection between these species has not been documented in sweet corn. Molecular gut-content analysis was conducted to test field-collected O. insidiosus for the presence of H. zea DNA using species-specific PCR primers developed and optimized for this project. Controlled feeding trials determined that the detectability half-life of this technique was 2.32 h. At peak predation in late August, 32% of O. insidiosus tested positive for H. zea DNA. The date of peak predation also corresponded with peak silking of sweet corn plants, which is the most attractive crop growth stage to both H. zea and O. insidiosus. These results indicate that within a short window prior to collection from the field, on the peak date of predation, approximately one third of O. insidiosus in sweet corn had consumed one to two H. zea eggs and/or first instar larvae. The demonstration of this high frequency of predation allows for the assertion that O. insidiosus is a critical mortality agent of H. zea in sweet corn, and conservation biological control practices should be explored to protect and promote this key predator

Maximizing geographical efficiency : An analysis of the configuration of Colorado’s trauma system

ACKNOWLEDGEMENT The data used for this study were supplied by the Health Facilities and Emergency Medical Services Division of the Colorado Department of Public Health and Environment, which specifically disclaims responsibility for any analyses, interpretations, or conclusions it has not provided. The data used for this study were supplied by the Health Facilities and Emergency Medical Services Division of the Colorado Department of Public Health and Environment, which specifically disclaims responsibility for any analyses, interpretations, or conclusions it has not provided.Peer reviewedPostprin

Strongly lensed [O III] emitters at Cosmic Noon with Roman: Characterizing extreme emission line galaxies on star cluster complex scales (100 pc)

Extreme emission line galaxies (EELGs) are considered the primary contributor to cosmic reionization and are valuable laboratories to study the astrophysics of massive stars. It is strongly expected that Roman's High Latitude Wide Area Survey (HLWAS) will find many strongly gravitationally lensed [O III] emitters at Cosmic Noon (1 < z < 2.8). Roman imaging and grism spectroscopy alone will simultaneously confirm these strong lens systems and probe their interstellar medium (ISM) and stellar properties on small scales ($\lesssim$ 100 pc). Moreover, these observations will synergize with ground-based and space-based follow-up observations of the discovered lensed [O III] emitters in multi-wavelength analyses of their properties (e.g., massive stars and possible escape of ionizing radiation), spatially resolved on the scales of individual star cluster complexes. Only Roman can uniquely sample a large number of lensed [O III] emitters to study the small scale (~ 100 pc) ISM and stellar properties of these extreme emission line galaxies, detailing the key physics of massive stars and the ISM that govern cosmic reionization.Comment: Submitted in response to the call for Roman Telescope CCS white paper

Effects of naltrexone on cortisol levels in heavy drinkers

The primary objectives of this study were to: (a) examine the neuroendocrine effects of naltrexone vs. placebo by comparing serum cortisol levels; and (b) test the biobehavioral correlates of naltrexone-induced changes in cortisol. Non-treatment seeking heavy drinkers (n = 37) completed two intravenous alcohol administrations, one after naltrexone (50 mg) and one after placebo. Cortisol levels were measured at baseline and after alcohol intake (BrAC = 0.06 g/dl) on both sessions, as were subjective responses to alcohol. Analyses revealed that naltrexone significantly raised overall cortisol levels compared to placebo. Cortisol levels decreased during alcohol administration and a stronger decrease was observed in the naltrexone condition. Cortisol levels were, in turn, inversely related to some of alcohol&apos;s the reinforcing effects (i.e., alcohol &apos;high,&apos; vigor) and positively associated with some of its unpleasant effects (i.e., sedation and subjective intoxication). These results suggest that naltrexone alters cortisol levels in heavy drinkers and that its effects on subjective responses to alcohol may be related, in part, to naltrexone&apos;s ability to activate the HPA-axis

11. Some aspects of enhancing natural pest control

Expert assessors Barbara Smith, Game and Wildlife Conservation Trust, UK Tony Harding, Rothamsted Research, UK Anthony Goggin, Linking Environment and Farming (LEAF), UK Felix Wackers, BioBest/University of Lancaster, Belgium/UK Melvyn Fidgett, Syngenta, UK Michael Garratt, University of Reading, UK Michelle Fountain, East Malling Research, UK Phillip Effingham, Greentech Consultants, UK Stephanie Williamson, Pesticides Action Network, UK Toby Bruce, Rothamsted Research, UK Andrew Wilby, Univ..