Meeting the Needs of Society and the Market

Notwithstanding the dramatic decline in law school enrollments over the past seven years, the number of law school graduates continues to significantly exceed the number of available entry-level bar-passage-required and J.D. advantage jobs. At the same time, millions of citizens have unmet legal needs because they cannot afford the cost of legal services. What does the future hold for law graduate employment? Will there be growth or contraction in particular areas of legal employment? Do we have a broad enough view of the law jobs of the future? What, if anything, can individual schools, or the legal academy as a whole, do to help bridge the justice gap? Should regulators do anything to respond to the changed environment, such as by adopting an employment rate accreditation standard or by tightening the bar passage standard

The ISCIP Analyst, Volume V, Issue 9

This repository item contains a single issue of The ISCIP Analyst, an analytical review journal published from 1996 to 2010 by the Boston University Institute for the Study of Conflict, Ideology, and Policy

Hanford Site Climatological Data Summary 2000 with Historical Data

This document presents the climatological data measured at the U.S. Department of Energy's Hanford Site for calendar year 2000

Comparison Of Heavy Metals In Aquatic Plants On Charity Island, Saginaw Bay, Lake Huron, U.S.A., With Plants Along The Shoreline Of Saginaw Bay

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/141439/1/ajb208285.pd

Selenomethionine and methyl selenocysteine: multiple-dose pharmacokinetics in selenium-replete men

According to the Nutritional Prevention of Cancer (NPC) trial, a selenized yeast supplement containing selenium, 200 mcg/day, decreased the incidence of total cancer, cancers of the prostate, colon and lung, and cancer mortality. The active agent in the selenized yeast supplement was assumed to be selenomethionine (SEMET), although the supplement had not been well speciated. The SELECT study, largely motivated by the NPC trial, enrolling nearly 40 times as many subjects, showed unequivocally that selenium 200 mcg/day, with selenium in the form of SEMET, does not protect selenium-replete men against prostate or other major cancer. The agent tested by SELECT, pure SEMET, could have been different from the selenized yeast tested in NPC. One of the selenium forms suspected of having chemopreventive effects, and which may have been present in the NPC agent, is methyl selenocysteine (MSC). This study, with 29 selenium-replete patients enrolled in a randomized, double-blind trial, compared the multiple-dose toxicity, pharmacokinetics and pharmacodynamics of MSC and SEMET. Patients were on trial for 84 days. No toxicity was observed. Although SEMET supplementation increased blood selenium concentration more than MSC did, neither form had a more than minimal impact on the two major selenoproteins: selenoprotein P(SEPP1) and glutathione peroxidase(GPX)

Prospectus, February 26, 1976

KEVIN WOODARD V.P.; PC news in brief: Auditions March 1, 2, SIU Reps Here March 5; Convocations starts \u27Forum\u27; Letters to the Editor; Comet West: Skylines; P/C Artists Compete In Junior College Art; Board of Trustees Notes; WPGU - Belle concert; Veterans\u27 election set; Prospectus guide to PC Slanguage ; Good News; Country Bouquet: Hank Williams; D.U. serves students; New Gym Lacks Needed Elevator; Disabled score difficulties; readers forum: Wife-beating problem one of brutality, tragedy; Classifieds; Dear Bonnie; It\u27s Debatable; Rozelle rule: Sports views; Cobra\u27s Corner; Who do we A-pre-ci-ate; PC attends ACU-I; Brown leads with 30: Cobras take CIAC Title; Medley takes first First: Tracksters take Third; CIAC Standings; Charity line tells the tale: Cobras fall to Lake Land End season with 88-77 loss; Spoon River falls 44-37: PC Women to State; O\u27Donnell wins Bob\u27s Bonanzahttps://spark.parkland.edu/prospectus_1976/1021/thumbnail.jp

The ANZUS Treaty during the Cold War: a reinterpretation of U.S. diplomacy in the Southwest Pacific

This article explains the origins of the Australia–New Zealand–United States (ANZUS) Treaty by highlighting U.S. ambitions in the Pacific region after World War II. Three clarifications to the historiography merit attention. First, an alliance with Australia and New Zealand reflected the pursuit of U.S. interests rather than the skill of antipodean diplomacy. Despite initial reservations in Washington, geostrategic anxiety and economic ambition ultimately spurred cooperation. The U.S. government's eventual recourse to coercive diplomacy against the other ANZUS members, and the exclusion of Britain from the alliance, substantiate claims of self-interest. Second, the historiography neglects the economic rationale underlying the U.S. commitment to Pacific security. Regional cooperation ensured the revival of Japan, the avoidance of discriminatory trade policies, and the stability of the Bretton Woods monetary system. Third, scholars have unduly played down and misunderstood the concept of race. U.S. foreign policy elites invoked ideas about a “White Man's Club” in Asia to obscure the pursuit of U.S. interests in the region and to ensure British exclusion from the treaty

Isolation and characterization of equine native MSC populations

Abstract Background In contrast to humans in which mesenchymal stem/stromal cell (MSC) therapies are still largely in the clinical trial phase, MSCs have been used therapeutically in horses for over 15 years, thus constituting a valuable preclinical model for humans. In human tissues, MSCs have been shown to originate from perivascular cells, namely pericytes and adventitial cells, which are identified by the presence of the cell surface markers CD146 and CD34, respectively. In contrast, the origin of MSCs in equine tissues has not been established, preventing the isolation and culture of defined cell populations in that species. Moreover, a comparison between perivascular CD146+ and CD34+ cell populations has not been performed in any species. Methods Immunohistochemistry was used to identify adventitial cells (CD34+) and pericytes (CD146+) and to determine their localization in relation to MSCs in equine tissues. Isolation of CD34+ (CD34+/CD146–/CD144–/CD45–) and CD146+ (CD146+/CD34–/CD144–/CD45–) cell fractions from equine adipose tissue was achieved by fluorescence-activated cell sorting. The isolated cell fractions were cultured and analyzed for the expression of MSC markers, using qPCR and flow cytometry, and for the ability to undergo trilineage differentiation. Angiogenic properties were analyzed in vivo using a chorioallantoic membrane (CAM) assay. Results Both CD34+ and CD146+ cells displayed typical MSC features, namely growth in uncoated tissue culture dishes, clonal growth when seeded at low density, expression of typical MSC markers, and multipotency shown by the capacity for trilineage differentiation. Of note, CD146+ cells were distinctly angiogenic compared with CD34+ and non-sorted cells (conventional MSCs), demonstrated by the induction of blood vessels in a CAM assay, expression of elevated levels of VEGFA and ANGPT1, and association with vascular networks in cocultures with endothelial cells, indicating that CD146+ cells maintain a pericyte phenotype in culture. Conclusion This study reports for the first time the successful isolation and culture of CD146+ and CD34+ cell populations from equine tissues. Characterization of these cells evidenced their distinct properties and MSC-like phenotype, and identified CD146+ cells as distinctly angiogenic, which may provide a novel source for enhanced regenerative therapies