Strategy for Cost-Effective Reduction of the Sum of Health Risk Estimates for Exposures to Mixtures of Toxic Substances

The authors argue that a minimization approach can provide guidance for effective use of funds to reduce the sum of estimated risks or the upper limit of the sum of risk estimates for mixtures of chemicals

Scalable data abstractions for distributed parallel computations

The ability to express a program as a hierarchical composition of parts is an essential tool in managing the complexity of software and a key abstraction this provides is to separate the representation of data from the computation. Many current parallel programming models use a shared memory model to provide data abstraction but this doesn't scale well with large numbers of cores due to non-determinism and access latency. This paper proposes a simple programming model that allows scalable parallel programs to be expressed with distributed representations of data and it provides the programmer with the flexibility to employ shared or distributed styles of data-parallelism where applicable. It is capable of an efficient implementation, and with the provision of a small set of primitive capabilities in the hardware, it can be compiled to operate directly on the hardware, in the same way stack-based allocation operates for subroutines in sequential machines

Structural trends in clusters of quadrupolar spheres

The influence of quadrupolar interactions on the structure of small clusters is investigated by adding a point quadrupole of variable strength to the Lennard-Jones potential. Competition arises between sheet-like arrangements of the particles, favoured by the quadrupoles, and compact structures, favoured by the isotropic Lennard-Jones attraction. Putative global potential energy minima are obtained for clusters of up to 25 particles using the basin-hopping algorithm. A number of structural motifs and growth sequences emerge, including star-like structures, tubes, shells and sheets. The results are discussed in the context of colloidal self-assembly.Comment: 8 pages, 6 figure

Test results of a 40-kW Stirling engine and comparison with the NASA Lewis computer code predictions

A Stirling engine was tested without auxiliaries at Nasa-Lewis. Three different regenerator configurations were tested with hydrogen. The test objectives were: (1) to obtain steady-state and dynamic engine data, including indicated power, for validation of an existing computer model for this engine; and (2) to evaluate structurally the use of silicon carbide regenerators. This paper presents comparisons of the measured brake performance, indicated mean effective pressure, and cyclic pressure variations from those predicted by the code. The silicon carbide foam generators appear to be structurally suitable, but the foam matrix showed severely reduced performance