Seismic Interpretation Integrated with Rock Physics and Petrophysical Analysis for the Characterization of 'JAY Field,' Niger Delta

Reservoir Characterization involves a holistic approach of describing a reservoir by integrating geologic, geophysical, petrophysical and reservoir engineering using all available data for the characterization of the reservoir’s geometric features (including structural and stratigraphic controls) and Petrophysical properties (including porosity, permeability and fluid saturation). The focus is to understand and identify the flow units of the reservoir and predict the inter-well distributions of relevant reservoir properties. JAY field was characterized via Petrophysical analysis, seismic interpretation and modelling, and rock physics analysis. Porosity and permeability models were generated and combined with petrophysical analysis in characterizing the delineated reservoirs. The rock physics cross-plots were used to quality check the results from the seismic and Petrophysical analysis. The structural interpretation of the 3D seismic data of the field revealed anticlinal structures (four-way closure) which is fault assisted and can thus allow hydrocarbon accumulation. Four of the faults are major listric faults that trend in the Northeast Southwest direction. Amongst the remaining fourteen minor faults, five of them are synthetic faults whose sense of displacement is similar to its associated major faults while others are Antithetic faults. Four horizons were established which indicated the top and base of the two reservoirs. The Petrophysical analysis indicated that the reservoirs have good pore interconnectivity (Average

Delay in the diagnosis of pulmonary tuberculosis in The Gambia, West Africa: A cross-sectional study.

OBJECTIVES: To investigate the pattern of tuberculosis (TB) care initiation and risk factors for TB diagnostic delay in The Gambia. METHODS: In this cross-sectional study, adult patients diagnosed with pulmonary TB (pTB) in public facilities in the Greater Banjul Area of The Gambia were consecutively recruited from October 2016 to March 2017. Diagnostic delay was defined as >21 days from the onset of at least one symptom suggestive of pTB to diagnosis. Logistic regression analyses were used to investigate risk factors for diagnostic delay. RESULTS: Overall, 216 pTB patients were included in the study; the median (Interquartile Range (IQR)) age was 30 (23-39) years and 167 (77%) were male patients. Of the 216 patients, 110 (50.9%) of them initiated care-seeking in the formal and informal private sector and 181/216 (83.8%) had TB diagnostic delay. The median (IQR) duration from the onset of symptoms to TB diagnosis was 34 (28-56) days. Age groups 18-29 years (aOR 3.2; 95% CI 1.2-8.8 [p = 0.02]) and 30-49 years (aOR 5.1; 95% CI 1.6-16.2 [p = 0.006]) and being employed (aOR 4.2; 95% CI 1.7-10.5 [p = 0.002]) were independent risk factors for TB diagnostic delay. CONCLUSION: There is considerable TB diagnostic delay in The Gambia, and this is likely to be worsened by the COVID-19 pandemic

The utilisation of virtual images in patient information giving sessions for prostate cancer patients prior to radiotherapy

© 2016 The College of RadiographersThe aim of the study was to explore the prostate patients' perceptions of a Virtual Environment for Radiotherapy Training (VERT) as an information giving resource prior to radiotherapy delivery. A survey design was used to determine the level of knowledge of those patients who attended VERT for a pre-treatment talk and identify the benefits and limitations of using VERT as pre-treatment information giving resource. Participants were invited to attend a VERT patient information session four weeks prior to their planning CT scan, and then complete a questionnaire two weeks after start of radiotherapy treatment. A sample of n = 38 patients were recruited over a five month data collection period. Results showed that patient perceptions on the use of VERT as information giving tool prior to radiotherapy treatment were very positive. The sessions enable patients to understand the potential impact of treatment volumes if the internal organ shape and location differed from that originally planned, enabling them to comply with radiotherapy treatment instructions. Additional key findings have demonstrated excellent levels of communication associated with the use of VERT emphasising the need for future patient preparation strategies to consider the use of virtual technology

Assessment of agro-ecological influence on the seed quality of groundnut (Arachis hypogaea) in The Gambia

A survey was conducted to assess the quality of groundnut seed produced and stored under ambient environment across various agro-ecologies of The Gambia, with a view to understanding regions with comparative advantage for its production and storage. Seed production activities of 60 seed growers in 26 communities were collected using structured questionnaires, interviews and observations. The Global Positioning System (GPS) coordinates of the communities were geo-referenced to identify the geographical positioning of the production sites. Samples of the groundnut pods were taken from the seed stores, threshed and subjected to seed quality analysis. Descriptive analysis was used to categorize the seed sources, hectarage cultivated, while seed quality data were subjected to analysis of variance of Nested Design. Means of significant factors were separated using Duncan Multiple Range Test (DMRT) at 5% significant level. The study showed that groundnut seed production is better concentrated in regions with optimum and sustainable rainfall that will reduce abiotic stress during seed development like the Lower River Region, West Coast Region and Central River Region. Fleur-11 variety was identified as one of the most promising varieties for groundnut cultivation in The Gambia and Tropical Africa

Developing and maintaining national food safety control systems: Experiences from the WHO African region

The establishment of effective food safety systems is pivotal to ensuring the safety of the national food supply as well as food products for regional and international trade. The development, structure and implementation of modern food safety systems have been driven over the years by a number of developments. These developments include: a reorientation of quality assurance protocols; emphasis on the development of integrated and holistic food safety systems with a farm-to-table approach; increasedrecognition of the respective roles of the different stakeholders along the food chain; increased food trade coupled with obligations under trade agreements; and advances in the control of foodborne hazards. At its core, a modern food safety system includes enabling food laws, policies, regulations and standards; mechanisms for coordination; operational food inspection and laboratory services as well as national information,education and communication programmes. While progress has been made in some countries in the WHO African Region at modernizing their food safety systems, many others are still grappling with the basics for development of effective food control systems. The traditional food control systems in a number of African countries do not provide the concerned agencies with a clear mandate and authority to prevent food safety problems. Effective food control in a number of these countries is undermined by a number of challenges including limited awareness about food safety, inadequate enabling policy, outdated legislation and regulations; inadequate coordination; and inadequate capacity and resources for food safety. This paper reviews the components of a modern national food safety control system and examines efforts at strengthening national food safety control systems in the African Region. It includesexperiences from countries that have made efforts at strengthening their national food safety control systems in view of current developments. The paper further discusses some of the challenges of food control systems in the Region and prospects for improvements. It concludes by suggesting the way forward for improving national food safety control systems in the Region

Lung cancer symptom appraisal, help-seeking and diagnosis - rapid systematic review of differences between patients with and without a smoking history

BACKGROUND: Lung cancer is the leading cause of cancer death in the world. A significant minority of lung cancer patients have never smoked (14% in the UK, and ranging from 10% to 25% worldwide). Current evidence suggests that never-smokers encounter delays during the diagnostic pathway, yet it is unclear how their experiences and reasons for delayed diagnoses differ from those of current and former smokers. This rapid review assessed literature about patient experiences in relation to symptom awareness and appraisal, help-seeking, and the lung cancer diagnostic pathway, comparing patients with and without a smoking history. METHODS: MEDLINE, PsychINFO and Google Scholar were searched for studies (2010-2020) that investigated experiences of the pathway to diagnosis for patients with and without a smoking history. Findings are presented using a narrative synthesis. RESULTS: Analysis of seven quantitative and three qualitative studies revealed that some delays during symptom appraisal and diagnosis are unique to never-smokers. Due to the strong link between smoking and lung cancer, and low awareness of non-smoking related lung cancer risk factors and symptoms, never-smokers do not perceive themselves to be at risk. Never-smokers are also likely to evaluate their experiences in comparison with other non-smoking related cancers, where prognosis is likely better, potentially leading to lower satisfaction with healthcare. CONCLUSION: Never-smokers appear to have different experiences in relation to symptom appraisal and diagnosis. However, evidence in relation to help-seeking, and what is driving diagnostic delays for never-smoker patients specifically is lacking

Grain yield response of Fonio (Digitaria exilis) varieties to fertilizer and cost- effectiveness under two different production systems in the Gambia

Fonio is an easy crop to grow because it grows well even on poor sandy soils, as well as in areas with low rainfall. The crop can withstand long dry  spells during the production season which are becoming a common occurrence in the West African subregion. In The Gambia, the common name  for the crop is “Findi”. It is commonly grown in fields that were previously cultivated with groundnut. Fonio is one of the oldest cereal crops grown in  the country; however, its cultivation has drastically declined to the extent that it is currently considered a minor crop in the country. Fonio is a very  fast-growing crop and matures earlier than most cereals. Its ability to withstand dry spells and its high nutritive value makes it an ideal climate-  smart crop. For this reason, there is renewed momentum in promoting the crop in the country. Despite these renewed efforts in its promotion,  there still exists a huge gap in terms of information on improved production practices that could help uplift the existing low yields. Appropriate  agronomic practices that can boost fonio productivity are not well documented at national level. To gather information on the input requirements  and utilizations, adaptability and productivity of fonio in The Gambia, experiments were conducted in 2018 and 2019 with the aim of generating  important production information that could guide efficient production and enhance productivity. Results obtained showed that fonio responded  positively to application of fertilizer. Application of 100 kg ha -1 comprising half NPK (15-15-15) and half urea was sufficient to produce financially  beneficial yields. Results also indicated that “Findiba”, which is a landrace may not be suitable for cultivation anymore due to its long growth period  amidst the short and erratic nature of the rainfall. The Momo and the Momosato varieties which are of shorter durations and high-yielding are more  suitable in the existing climatic conditions of the country

Further evidence supporting a role for gs signal transduction in severe malaria pathogenesis.

With the functional demonstration of a role in erythrocyte invasion by Plasmodium falciparum parasites, implications in the aetiology of common conditions that prevail in individuals of African origin, and a wealth of pharmacological knowledge, the stimulatory G protein (Gs) signal transduction pathway presents an exciting target for anti-malarial drug intervention. Having previously demonstrated a role for the G-alpha-s gene, GNAS, in severe malaria disease, we sought to identify other important components of the Gs pathway. Using meta-analysis across case-control and family trio (affected child and parental controls) studies of severe malaria from The Gambia and Malawi, we sought evidence of association in six Gs pathway candidate genes: adenosine receptor 2A (ADORA2A) and 2B (ADORA2B), beta-adrenergic receptor kinase 1 (ADRBK1), adenylyl cyclase 9 (ADCY9), G protein beta subunit 3 (GNB3), and regulator of G protein signalling 2 (RGS2). Our study amassed a total of 2278 cases and 2364 controls. Allele-based models of association were investigated in all genes, and genotype and haplotype-based models were investigated where significant allelic associations were identified. Although no significant associations were observed in the other genes, several were identified in ADORA2A. The most significant association was observed at the rs9624472 locus, where the G allele (approximately 20% frequency) appeared to confer enhanced risk to severe malaria [OR = 1.22 (1.09-1.37); P = 0.001]. Further investigation of the ADORA2A gene region is required to validate the associations identified here, and to identify and functionally characterize the responsible causal variant(s). Our results provide further evidence supporting a role of the Gs signal transduction pathway in the regulation of severe malaria, and request further exploration of this pathway in future studies