5 research outputs found
Bard song as a method of developing moral values in junior schoolchildren=Авторская песня как средство формирования нравственных ориентиров младших школьников
The article says that the author's songs are an excellent tool for the realization of educational objectives and the best way to the humanization of modern Russian education. Many bard songs have both the adult and children's audience. During the performance of a song, its text content forms the joint moral and ethical work of a teacher and a studen
Clinical characteristics of Polish patients with ANCA-associated vasculitides-retrospective analysis of POLVAS registry
Objective Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV) are rare small to medium-size
vessel systemic diseases. As their clinical picture, organ involvement, and factors influencing outcome may differ
between countries and geographical areas, we decided to describe a large cohort of Polish AAV patients coming from
several referral centers-members of the Scientific Consortium of the Polish Vasculitis Registry (POLVAS).
Methods We conducted a systematic multicenter retrospective study of adult patients diagnosed with AAV between
Jan 1990 and Dec 2016 to analyze their clinical picture, organ involvement, and factors influencing outcome. Patients
were enrolled to the study by nine centers (14 clinical wards) from seven Voivodeships populated by 22.3 mln inhabitants (58.2% of the Polish population).
Results Participating centers included 625 AAV patients into the registry. Their distribution was as follows: 417 patients
(66.7%) with GPA, 106 (17.0%) with MPA, and 102 (16.3%) with EGPA. Male-to-female ratios were almost 1:1 for
GPA (210/207) and MPA (54/52), but EGPA was twice more frequent among women (34/68). Clinical manifestations
and organ involvement were analyzed by clinical phenotype. Their clinical manifestations seem very similar to other
European countries, but interestingly, men with GPA appeared to follow a more severe course than the women. Fifty five
patients died. In GPA, two variables were significantly associated with death: permanent renal replacement therapy
(PRRT) and respiratory involvement (univariate analysis). In multivariate analysis, PRRT (OR = 5.3; 95% confidence interval (CI) = 2.3–12.2), respiratory involvement (OR = 3.2; 95% CI = 1.06–9.7), and, in addition, age > 65 (OR = 2.6;
95% CI = 1.05–6.6) were independently associated with death. In MPA, also three variables were observed to be
independent predictors of death: PRRT (OR = 5.7; 95% CI = 1.3–25.5), skin involvement (OR = 4.4; 95% CI = 1.02–
19.6), and age > 65 (OR = 6.3; 95% CI = 1.18–33.7).
Conclusions In this first multicenter retrospective study of the Polish AAV patients, we have shown that their demographic
characteristics, disease manifestations, and predictors of fatal outcome follow the same pattern as those from other European
countries, with men possibly suffering from more severe course of the disease
Bard song as a method of developing moral values in junior schoolchildren-Авторская песня как средство формирования нравственных ориентиров младших школьников
The article says that the author's songs are an excellent tool for the realization of educational objectives and the best way to the humanization of modern Russian education. Many bard songs have both the adult and children's audience. During the performance of a song, its text content forms the joint moral and ethical work of a teacher and a studen