20 research outputs found

    The Czech customer's approach to quality of textile products

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    Cílem této bakalářské práce je najít to, co si český spotřebitel představí pod pojmem kvalita textilního výrobku. Za pomoci dotazníkového šetření, kde bylo použito 17 vlastností textilního výrobku, byly vymezeny ty nejdůležitější pro českéhospotřebitele. Dále je český spotřebitel porovnán s polským.The aim of this work is to find what the Czech customer's introduces the concept of quality textile products. With the help of a questionnaire survey, which used 17 textile product characteristics have been defined the most important for Czech customers. Further is the Czech customer compared with the Polish

    Ferric Reducing Antioxidant Power and Square Wave Voltammetry for Assay of Low Molecular Weight Antioxidants in Blood Plasma: Performance and Comparison of Methods

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    The purpose of the present study was to employ two methods—square wave voltammetry (SWV) performed on screen printed sensors and ferric reducing antioxidant power (FRAP)—as suitable tools for the assay of low-molecular-weight antioxidants (LMWAs). LMWAs were assayed by both methods and the resulting data were statistically compared. Plasma samples from five Cinereous vultures accidentally intoxicated with lead were used to represent real biological matrices with different levels of LMWAs. Blood was collected from the birds prior to and one month after treatment with Ca-EDTA. SWV resulted in two peaks. The first peak, with the potential value of 466 ± 15 mV, was recognized as ascorbic and uric acids, while the second one (743 ± 30 mV) represented glutathione, tocopherol, ascorbic acid and in a minor effect by uric acid, too. Contribution of individual antioxidants was recognized by separate assays of LMWA standards. Correlation between peaks 1 and 2 as well as the sum of the two peaks and FRAP was analysed. While peak 1 and the sum of peaks were in close correlation to FRAP results (correlation coefficient of 0.97), the relation between peak 2 and FRAP may be expressed using a correlation coefficient of 0.64. The determination of thiols by the Ellman assay confirmed the accuracy of SWV. Levels of glutathione and other similar structures were stable in the chosen model and it may be concluded that SWV is appropriate for assay of LMWAs in plasma samples. The methods employed in the study were advantageous in minimal sample volume consumption and fast acquisition of results

    Wyzwania systemowe stojące przed hematologią onkologiczną w aspekcie starzejącego się społeczeństwa w Polsce

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    The aging population and the increasing incidence of hematological malignancies is a challenge for the health care system in Poland. New medical technologies offer opportunities for patients above 65 years of age. Their use, however, requires careful research and confirm their usefulness in the context of current therapeutic guidelines. The requirement for patient access to modern medical technologies is to optimize operations and adequate funding of the healthcare system. It appears that the area of oncological hematology can be a model for effective solutions to the system, with the patient, as the subject of the system.Starzenie się społeczeństwa i wzrastająca zapadalność na nowotwory hematologiczne jest wyzwaniem dla systemu ochrony zdrowia. Nowotwory hematologiczne stanowiły około 5% wszystkich zachorowań na nowotwory ogółem w 2012 roku, a połowa chorych miała ponad 65 lat. Nowe standardy leczenia oraz technologie medyczne stwarzają szanse dla chorych, ale ich zastosowanie wymaga wnikliwych badań oraz potwierdzenia użyteczności w ramach praktyki klinicznej. Warunkami adekwatnego dostępu pacjentów w Polsce do technologii medycznych w ramach aktualnych standardów terapeutycznych są optymalizacja i adekwatne finansowanie systemu opieki zdrowotnej. Wydaje się, że hematologia onkologiczna może być modelowym przykładem efektywnych rozwiązań systemowych — z pacjentem jako podmiotem tego systemu

    Population and labour force projections for 27 European countries, 2002-052: impact of international migration on population ageing: Projections de population et de population active pour 27 pays européens 2002-052: impact de la migration internationale sur le vieillissement de la population

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    Population and labour force projections are made for 27 selected European countries for 2002-052, focussing on the impact of international migration on population and labour force dynamics. Starting from single scenarios for fertility, mortality and economic activity, three sets of assumptions are explored regarding migration flows, taking into account probable policy developments in Europe following the enlargement of the EU. In addition to age structures, various support ratio indicators are analysed. The results indicate that plausible immigration cannot offset the negative effects of population and labour force ageing

    Mitochondrial physiology

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    As the knowledge base and importance of mitochondrial physiology to evolution, health and disease expands, the necessity for harmonizing the terminology concerning mitochondrial respiratory states and rates has become increasingly apparent. The chemiosmotic theory establishes the mechanism of energy transformation and coupling in oxidative phosphorylation. The unifying concept of the protonmotive force provides the framework for developing a consistent theoretical foundation of mitochondrial physiology and bioenergetics. We follow the latest SI guidelines and those of the International Union of Pure and Applied Chemistry (IUPAC) on terminology in physical chemistry, extended by considerations of open systems and thermodynamics of irreversible processes. The concept-driven constructive terminology incorporates the meaning of each quantity and aligns concepts and symbols with the nomenclature of classical bioenergetics. We endeavour to provide a balanced view of mitochondrial respiratory control and a critical discussion on reporting data of mitochondrial respiration in terms of metabolic flows and fluxes. Uniform standards for evaluation of respiratory states and rates will ultimately contribute to reproducibility between laboratories and thus support the development of data repositories of mitochondrial respiratory function in species, tissues, and cells. Clarity of concept and consistency of nomenclature facilitate effective transdisciplinary communication, education, and ultimately further discovery

    Mitochondrial physiology

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    As the knowledge base and importance of mitochondrial physiology to evolution, health and disease expands, the necessity for harmonizing the terminology concerning mitochondrial respiratory states and rates has become increasingly apparent. The chemiosmotic theory establishes the mechanism of energy transformation and coupling in oxidative phosphorylation. The unifying concept of the protonmotive force provides the framework for developing a consistent theoretical foundation of mitochondrial physiology and bioenergetics. We follow the latest SI guidelines and those of the International Union of Pure and Applied Chemistry (IUPAC) on terminology in physical chemistry, extended by considerations of open systems and thermodynamics of irreversible processes. The concept-driven constructive terminology incorporates the meaning of each quantity and aligns concepts and symbols with the nomenclature of classical bioenergetics. We endeavour to provide a balanced view of mitochondrial respiratory control and a critical discussion on reporting data of mitochondrial respiration in terms of metabolic flows and fluxes. Uniform standards for evaluation of respiratory states and rates will ultimately contribute to reproducibility between laboratories and thus support the development of data repositories of mitochondrial respiratory function in species, tissues, and cells. Clarity of concept and consistency of nomenclature facilitate effective transdisciplinary communication, education, and ultimately further discovery
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