94 research outputs found
Radiographic Union Scoring Scale for Determining Consolidation Rates in the Calcaneus.
The reliable evaluation of osseous consolidation after hindfoot osteotomy can be difficult. Concomitant hindfoot osteotomies often dictate the advancement of weightbearing, and radiographs are the mainstay imaging tool owing to cost, efficiency, and radiation exposure. Understanding the radiographic parameters that can be used to reliably determine osseous healing is paramount. However, currently, no reliable or validated method is available to determine osseous healing of hindfoot osteotomies in irregular bones of the foot. The purpose of the present study was to develop a radiographic healing scoring system that would enhance the diagnostic healing assessment after elective calcaneal osteotomy. We adapted existing orthopedic scales validated for healing in the leg for application in the irregular bones of the foot. A total of 168 cases were evaluated by 6 blinded assessors to test the interrater reliability of subjective healing assessment compared with the proposed scoring system. The radiographs were classified by postoperative period: ≤4 weeks, 5 to 12 weeks, and \u3e12 weeks. The proposed scale had high interrater reliability but was burdensome. Using a priori item reduction protocols, a limited 6-item scale further improved internal consistency and reduced the burden. The result was excellent interrater reliability (α = 0.98, standard deviation 0.02, 95% confidence interval 0.91 to 0.96) among all assessors when using the scoring scale compared with unacceptable reliability (α = 0.438) for subjective osteotomy healing. The reliability of our system appeared superior to that of subjective assessment of osseous healing alone, even in the absence of clinical correlates after osteotomy of the calcaneus
Following the Science: the role of the academic medical center in the COVID-19 pandemic
This article reviews the experience and role of an academic medical center in a response to the COVID-19 pandemic
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Highly selective and solvent-dependent reduction of Nitrobenzene to N-phenylhydroxylamine, azoxybenzene, and aniline catalyzed by phosphino-modified polymer immobilized ionic liquid-stabilized AuNPs
Gold nanoparticles stabilized by phosphine-decorated polymer immobilized ionic liquids (AuNP@PPh2-PIILP) is an extremely efficient multiproduct selective catalyst for the sodium borohydride-mediated reduction of nitrobenzene giving N-phenylhydroxylamine, azoxybenzene, or aniline as the sole product under mild conditions and a very low catalyst loading. The use of a single nanoparticle-based catalyst for the partial and complete reduction of nitroarenes to afford three different products with exceptionally high selectivities is unprecedented. Under optimum conditions, thermodynamically unfavorable N-phenylhydroxylamine can be obtained as the sole product in near quantitative yield in water, whereas a change in reaction solvent to ethanol results in a dramatic switch in selectivity to afford azoxybenzene. The key to obtaining such a high selectivity for N-phenylhydroxylamine is the use of a nitrogen atmosphere at room temperature as reactions conducted under an inert atmosphere occur via the direct pathway and are essentially irreversible, while reactions in air afford significant amounts of azoxy-based products by virtue of competing condensation due to reversible formation of N-phenylhydroxylamine. Ultimately, aniline can also be obtained quantitatively and selectively by adjusting the reaction temperature and time accordingly. Introduction of PEG onto the polyionic liquid resulted in a dramatic improvement in catalyst efficiency such that N-phenylhydroxylamine could be obtained with a turnover number (TON) of 100 000 (turnover frequency (TOF) of 73 000 h–1, with >99% selectivity), azoxybenzene with a TON of 55 000 (TOF of 37 000 h–1 with 100% selectivity), and aniline with a TON of 500 000 (TOF of 62 500 h–1, with 100% selectivity). As the combination of ionic liquid and phosphine is required to achieve high activity and selectivity, further studies are currently underway to explore whether interfacial electronic effects influence adsorption and thereby selectivity and whether channeling of the substrate by the electrostatic potential around the AuNPs is responsible for the high activity. This is the first report of a AuNP-based system that can selectively reduce nitroarenes to either of two synthetically important intermediates as well as aniline and, in this regard, is an exciting discovery that will form the basis to develop a continuous flow process enabling facile scale-up
PEARLS: Low Stellar Density Galaxies in the El Gordo Cluster Observed with JWST
A full understanding of how unusually large "Ultra Diffuse Galaxies" (UDGs)
fit into our conventional understanding of dwarf galaxies remains elusive,
despite the large number of objects identified locally. A natural extension of
UDG research is the study of similar galaxies at higher redshift to establish
how their properties may evolve over time. However, this has been a challenging
task given how severely systematic effects and cosmological surface brightness
dimming inhibit our ability to study low-surface brightness galaxies at
high-. Here, we present an identification of low stellar surface density
galaxies (LDGs), likely the progenitors of local UDGs, at moderate redshift
with deep near-IR observations of the El Gordo cluster at with JWST.
By stacking 8 NIRCAM filters, we are able to achieve an apparent surface
brightness sensitivity of mag arcsec, faint enough to be
complete to the bright end of the LDG population. Our analysis identifies
significant differences between this population and local UDGs, such as their
color and size distributions, which suggest that UDG progenitors are bluer and
more extended at high- than at . This suggests that multiple
mechanisms are responsible for UDG formation and that prolonged transformation
of cluster dwarfs is not a primary UDG formation mechanism at high-.
Furthermore, we find a slight overabundance of LDGs in El Gordo, and, in
contrast to findings in local clusters, our analysis does not show a deficit of
LDGs in the center of El Gordo, implying that tidal destruction of LDGs is
significant between and .Comment: Resubmitted to ApJ after minor revision
JWST NIRCam Photometry: A Study of Globular Clusters Surrounding Bright Elliptical Galaxy VV 191a at z=0.0513
James Webb Space Telescope NIRCam images have revealed 443 globular cluster
(GC) candidates around the elliptical galaxy VV 191a. NIRCam
broadband observations are made at 0.9-4.5 m using filters F090W, F150W,
F356W, and F444W. Using photometry, the data is analyzed to present
color-magnitude diagrams (CMDs) that suggest a fairly uniform population of
GCs. Color histograms show a unimodal color distribution that is well fit by a
single Gaussian, using color to primarily trace the metallicity. The findings
show the sample's globular cluster luminosity function (GCLF) does not reach
the turnover value and is, therefore, more luminous than what is typically
expected, with an absolute AB magnitude, mag, reaching
within nearly one magnitude of the classical turnover value. We attribute this
to the completeness in the sample. Models show that the mass estimate of the
GCs detected tends to be more massive, reaching upward of . However, the results show that current GC models do not quite align
with the data. We find that the models appear to be bluer than the JWST data in
the reddest (F356W-F444W) filters and redder than the data in the bluest
(F090W-F150W) filters and may need to be revised to improve the modeling of
near-IR colors of old, metal-poor stellar populations.Comment: 11 pages, 7 figure
EPOCHS VII: Discovery of high redshift () AGN candidates in JWST ERO and PEARLS data
We present an analysis of a sample of robust high redshift galaxies selected
photometrically from the `blank' fields of the Prime Extragalactic Areas for
Reionization Science (PEARLS) survey and Early Release Observations (ERO) data
of the James Webb Space Telescope (JWST) with the aim of selecting candidate
high redshift active galactic nuclei (AGN). Sources were identified from the
parent sample using a threefold selection procedure, which includes spectral
energy distribution (SED) fitting to identify sources that are best fitted by
AGN SED templates, a further selection based on the relative performance of AGN
and non-AGN models, and finally morphological fitting to identify compact
sources of emission, resulting in a purity-oriented procedure. Using this
procedure, we identify a sample of nine AGN candidates at , from
which we constrain their physical properties as well as measure a lower bound
on the AGN fraction in this redshift range of \%. As this is an
extreme lower limit due to our focus on purity and our SEDs being calibrated
for unobscured Type 1 AGN, this demonstrates that AGN are perhaps quite common
at this early epoch. The rest-frame UV colors of our candidate objects suggest
that these systems are potentially candidate obese black hole galaxies (OBG),
or AGN with very little galaxy component. We also investigate emission from our
sample sources from fields overlapping with Chandra and VLA surveys, allowing
us to place X-ray and 3 GHz radio detection limits on our candidates. Of note
is a candidate source exhibiting an abrupt morphological shift in
the reddest band as compared to the bluer bands, indicating a potential merger
or an unusually strong outflow.Comment: Submitted to MNRAS, 12 pages, 11 figures, typos correcte
Magellanic System Stars Identified in the SMACS J0723.3-7327 JWST ERO Images
We identify 68 distant stars in JWST/NIRCam ERO images of the field of galaxy
cluster SMACS J0723.3-7327 (SMACS 0723). Given the relatively small
() angular separation between SMACS 0723 and the Large
Magellanic Cloud, it is likely that these stars are associated with the LMC
outskirts or Leading Arm. This is further bolstered by a spectral energy
distribution analysis, which suggests an excess of stars at a physical distance
of kpc, consistent with being associated with or located behind the
Magellanic system. In particular, we find that the overall surface density of
stars brighter than 27.0 mag in the field of SMACS 0723 is 2.3 times that
of stars in a blank field with similar galactic latitude (the North Ecliptic
Pole Time Domain Field), and that the density of stars in the SMACS 0723 field
with SED-derived distances consistent with the Magellanic system is 7.3
times larger than that of the blank field. The candidate stars at these
distances are consistent with a stellar population at the same distance modulus
with [Fe/H] and an age of Gyr. On the assumption that all
of the 68 stars are associated with the LMC, then the stellar density of the
LMC at the location of the SMACS 0723 field is stars kpc,
which helps trace the density of stars in the LMC outskirts.Comment: Submitted to ApJ, comments welcom
PEARLS: A Potentially Isolated Quiescent Dwarf Galaxy with a TRGB Distance of 31 Mpc
A wealth of observations have long suggested that the vast majority of
isolated classical dwarf galaxies (- M) are currently
star-forming. However, recent observations of the large abundance of
"Ultra-Diffuse Galaxies" beyond the reach of previous large spectroscopic
surveys suggest that our understanding of the dwarf galaxy population may be
incomplete. Here we report the serendipitous discovery of an isolated quiescent
dwarf galaxy in the nearby Universe, which was imaged as part of the PEARLS GTO
program. Remarkably, individual red-giant branch stars are visible in this
near-IR imaging, suggesting a distance of Mpc, and a wealth of archival
photometry point to an sSFR of yr. Spectra obtained
with the Lowell Discovery Telescope find a recessional velocity consistent with
the Hubble Flow and km/s separated from the nearest massive galaxy in
SDSS, suggesting that this galaxy was either quenched from internal mechanisms
or had a very high-velocity interaction with a nearby massive galaxy in the
past. This analysis highlights the possibility that many nearby quiescent dwarf
galaxies are waiting to be discovered and that JWST has the potential to
identify them.Comment: Submitted to ApJ Letters. Comments welcome
Are JWST/NIRCam color gradients in the lensed z=2.3 dusty star-forming galaxy El Anzuelo due to central dust attenuation or inside-out galaxy growth?
Gradients in the mass-to-light ratio of distant galaxies impede our ability
to characterize their size and compactness. The long-wavelength filters of
's NIRCam offer a significant step forward. For galaxies at Cosmic Noon
(), this regime corresponds to the rest-frame near-infrared, which is
less biased towards young stars and captures emission from the bulk of a
galaxy's stellar population. We present an initial analysis of an extraordinary
lensed dusty star-forming galaxy (DSFG) at behind the
cluster (), named ("The Fishhook") after its partial
Einstein-ring morphology. The FUV-NIR SED suggests an intrinsic star formation
rate of and dust attenuation , in line with other DSFGs on the star-forming main sequence. We develop a
parametric lens model to reconstruct the source-plane structure of dust imaged
by the Atacama Large Millimeter/submillimeter Array, far-UV to optical light
from , and near-IR imaging with 8 filters of /NIRCam, as part of
the Prime Extragalactic Areas for Reionization and Lensing Science (PEARLS)
program. The source-plane half-light radius is remarkably consistent from m, despite a clear color gradient where the inferred galaxy center is
redder than the outskirts. We interpret this to be the result of both a
radially-decreasing gradient in attenuation and substantial spatial offsets
between UV- and IR-emitting components. A spatial decomposition of the SED
reveals modestly suppressed star formation in the inner kiloparsec, which
suggests that we are witnessing the early stages of inside-out quenching.Comment: 29 pages, 11 figures, 5 tables. Accepted for publication in Ap
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