11 research outputs found

    Heterosis for yield and yield attributes in rice (Oryza sativa L.)

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    The present study was carried out to study the extent of heterosis, heterobeltiosis and standard heterosis for yield and yield parameters in rice. Analysis of variance indicated significant difference among the genotypes for various traits. Estimation of heterosis for various yield contributing traits indicated that out of nine crosses studied, Pusa sugandh-2 X BPT-5204 (27.93) and Pusa sugandh-2 X Kasturi (24.71) were identified as promising. These hybrids may be recommended for commercial cultivation after further evaluation

    Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of indeterminate potential

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    Human genetic studies support an inverse causal relationship between leukocyte telomere length (LTL) and coronary artery disease (CAD), but directionally mixed effects for LTL and diverse malignancies. Clonal hematopoiesis of indeterminate potential (CHIP), characterized by expansion of hematopoietic cells bearing leukemogenic mutations, predisposes both hematologic malignancy and CAD. TERT (which encodes telomerase reverse transcriptase) is the most significantly associated germline locus for CHIP in genome-wide association studies. Here, we investigated the relationship between CHIP, LTL, and CAD in the Trans-Omics for Precision Medicine (TOPMed) program (n = 63,302) and UK Biobank (n = 47,080). Bidirectional Mendelian randomization studies were consistent with longer genetically imputed LTL increasing propensity to develop CHIP, but CHIP then, in turn, hastens to shorten measured LTL (mLTL). We also demonstrated evidence of modest mediation between CHIP and CAD by mLTL. Our data promote an understanding of potential causal relationships across CHIP and LTL toward prevention of CAD

    Variability, heritability and genetic advance studies in some indigenous genotypes of basmati rice (Oryza sativa L.)

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    The investigation conducted with 25 rice genotypes comprising both Basmati and non-basmati types revealed significant differences among the genotypes for the yield, its components and some grain quality characteristics. The magnitude of differences between PCV and GCV was relatively low for all the traits, indicating less environmental influence. The GCV was higher for the characters alkali spread value, yield per plant and effective panicles. High heritability coupled with high genetic advance as per cent of mean was recorded for days to 50% flowering, plant height, panicle length, effective panicles per plant, spikelets per panicle, filled grains per panicle, test weight, yield per plant, brown rice length, brown rice L/B ratio, kernel length, kernel L/B ratio, kernel length after cooking, elongation ratio and alkali spread value indicating the additive gene effects in the genetic control of these traits and can be improved by simple selection in the present breeding material
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