19 research outputs found
Study - High seroprevalence of HSV-1 and HSV-2 in STD clinic attendees and non-high risk controls: A case control study at a referral hospital in South India
BACKGROUND: In Asia, HSV seroprevalence studies are sparse and they
have recorded lower prevalence of HSV infection, especially HSV-2.
AIMS: To ascertain the seroprevalence of HSV-1 and HSV-2 in patients
attending a STD clinic in a referral hospital in south India and to
compare it with a control group. METHODS: The study included 135
consecutive STD cases having history of ulcerative or non-ulcerative
STD in the present or in the past 5 years and 135 age and sex-matched
controls. Diagnostic serology was done for HSV-1 and HSV-2 using type
specific IgG by indirect immunoassay using ELISA. The results were
analyzed utilizing Chi- square test. RESULTS: Amongst 135 STD clinic
cases, 106 cases were males and 29 cases were females with male to
female ratio of 3.65:1. The mean age was 32.2 years (range 16-65
years). Among study group cases, 112 (82.9%) cases were co-infected
with HSV-1 and HSV-2, 11 (8.1%) cases were seropositive for HSV-1 alone
and 3 (2.2%) cases were seropositive for HSV-2 alone. In the control
group, 112 (82.9%) cases were co-infected with HSV-1 and 2, 12 (9.6%)
for HSV-1 alone and 1(0.8%) for HSV-2 alone. Correlation of HSV-1 and
HSV-2 serology with various demographic and behavioral factors was
statistically insignificant. CONCLUSIONS: Seroprevalence of HSV-1 and
HSV-2 in STD clinic cases and control group is high, similar to that
recorded in sub-Saharan Africa. Thus, serological studies for HSV-1 and
HSV-2 cannot be taken as a marker of sexual behavior in our set of
population
Effect of anti retroviral therapy on mucocutaneous manifestations among HIV infected patients in a tertiary care centre in India
Net Study - A clinical study of skin changes in pregnancy
Background: During pregnancy profound immunologic, metabolic, endocrine
and vascular changes occur, that are responsible for the changes of the
skin and its appendages, both physiologic and pathologic. Aims: We
undertook a clinical study to find out the frequency and pattern of
skin changes in pregnant women. Methods: All consecutive pregnant
women were included in the study. Results: A total of 607 pregnant
women were included in this study. Of these, 303(49.9%) pregnant women
were primigravida and 304(51.1%) were multigravida. Skin changes
grouped into: physiological changes (all cases), specific dermatoses
(22 cases) and other dermatoses affected by pregnancy (125 cases). Most
common physiological changes were pigmentary alterations seen in 555
(91.4%) followed by striae seen in 484(79.7%) cases. Of the various
specific dermatoses of pregnancy, pruritic urticarial papules and
plaques of pregnancy (PUPPP) was the most common disorder (14 cases)
followed by pruritus gravidarum (5 cases). The most common dermatoses
affected by pregnancy were candidal vaginitis (17 cases), acne vulgaris
(15 cases), skin tags (15 cases), eczemas (14 cases). Conclusion:
This study brings into focus various skin changes during pregnancy in
south India
High seroprevalence of HSV-1 and HSV-2 in STD clinic attendees and non-high risk controls: A case control study at a referral hospital in South India
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