PlantDoc: A Dataset for Visual Plant Disease Detection

India loses 35% of the annual crop yield due to plant diseases. Early detection of plant diseases remains difficult due to the lack of lab infrastructure and expertise. In this paper, we explore the possibility of computer vision approaches for scalable and early plant disease detection. The lack of availability of sufficiently large-scale non-lab data set remains a major challenge for enabling vision based plant disease detection. Against this background, we present PlantDoc: a dataset for visual plant disease detection. Our dataset contains 2,598 data points in total across 13 plant species and up to 17 classes of diseases, involving approximately 300 human hours of effort in annotating internet scraped images. To show the efficacy of our dataset, we learn 3 models for the task of plant disease classification. Our results show that modelling using our dataset can increase the classification accuracy by up to 31%. We believe that our dataset can help reduce the entry barrier of computer vision techniques in plant disease detection.Comment: 5 Pages, 6 figures, 3 table

Prospective study of management of long bone fracture by intra-medullary elastic nailing in children

Background: The treatment of long bone fractures in children from 6 to 14 years is a challenging scenario. Titanium elastic nail (TEN) fixation was originally meant as a gold standard treatment method for femoral fractures, but was gradually applied to other long bone fractures in children, because it represents a middle path between conservative and surgical modality.Methods: In the present study paediatric patients in the age group of 6 to 14 year with long bone fractures to be treated with TEN in the Department of Orthopaedics were admitted to MGM Hospital (Kamothe) were selected. A total of 30 patients consenting to undergo this study were subjected for treatment after screening using the inclusion and exclusion criteria.Results: The mean age of the patients was 9.67±2.68 years. There was male preponderance (63.3%). In our study, RTA was observed to be the main cause of fracture (80%) whereas 20% fractures were due to fall. In our study, 50% patients had fracture of radius ulna followed by fracture of tibia 23.3%, femur (23.3%), and humerus (3.3%). The mean time to union was 5.30±1.06 weeks.Conclusions: TEN seems to be simple, biocompatible, more physiological, reliable and effective method of treatment of all long bone shaft fractures in 6 to 14 years old children. It is a rapid, safe and simple procedure with advantages of short operative time, minimal blood loss, shorter hospital stays early union, allowing early mobilization and early return to function with minimal complications

A prospective study of management of distal end of radius fracture in children

Background: Distal end radius (DER) fractures represents one of the common fractures in the paediatric age group. Most of this injury are managed by closed reduction and casting. We investigated the degree to which the clinical and radiographic follow-ups reveal complications that lead to a change in management of the un-manipulated distal radius fractures in children less than 14 years of age. We determined the frequency and type of complications registered during treatment, and assessed the stability of the different fracture types.Methods: Study includes examination of 30 patients with closed DER fractures who were admitted in tertiary care centre between August 2016 to April 2018.Results: Closed reduction and casting was modality of treatment in 40%, casting was done in 33.3% and closed reduction and k wire were done in 26.7%. In patients with closed reduction and k wire slab was given. Gartland and Werley’s scoring system was used and found that 60% patients have 0 score, 30% have 1 score, 6.7% have 2 score and 3.3% have 3 score. 29 patients had excellent result and 1 patient had fair result.Conclusions: In this study of management of DER fracture in children with different modality of treatment, we noted that if it is an undisplaced fracture, can be managed with casting. If it is displaced fracture and reduction is achieved then closed reduction and casting can be done. If displacement is more than 50% of bone diameter then closed reduction and k wire can be done

Fabrication and Evaluation of Herbal Hair Gel containing Zizipus jujuba, Hibiscus and Piper nigrum

Hair is an imperative part of human body. Various synthetic compounds, chemicals, and their derivatives have been proved to cause destructive effects. A number of herbal principles have been commended with hair growth promoting action and formulating them into appropriate cosmeceuticals can be well acknowledged as far as the patient compliance is concerned. The objective of the present research work was to develop a hair gel formulation with Black pepper (Piper nigrum) which is often used in Ayurvedic medicines and it stimulates hair follicles causing growth, and with Hibiscus leaves extract which is known as a hair growth promoter and a hair conditioner as well. The formulations also contain Ziziphus jujuba leaves extract, which has been reported possessing antibacterial activity which makes it beneficial against dandruff and scalp infections. Along with extracts of Ziziphus jujuba and Hibiscus leaves and Black Pepper seeds (3% w/w each). All the ingredients used to prepare the hair gel was found harmless and the physicochemical assessment showed ideal results, but advance research is required to perceive its hair growth promotion property. Keywords:  Ziziphus jujuba, Piper nigrum , Hibiscus, Hair Ge

In silico interaction of Berberine with some immunomodulatory targets: A docking analysis

Plant, mineral, and animal products have been utilized as medications from the beginning of time to cure a variety of ailments. Use of medicinal herbs to modulate immune function has a rich history. Natural products serve as the foundation for contemporary pharmaceutical ingredients. Immunomodulation alters an individual's immune system by interfering with its normal processes. Immunomodulators derived from natural sources have been extensively studied in order to modify the immune system and prevent illness. Berberine is an alkaloid has been identified for its anti-inflammatory properties. In animal studies, Berberine was found to demonstrate analgesic properties. The current work is aimed to explore the in silico interactions of Berberine with various chemokines and inflammatory pathways. Berberine was docked with TNF-α, IL-1β, IL-6, and NOs in this investigation. Docking study demonstrated notable interactions with these targets. The present research provides insight into the development of new compounds for immunomodulation and the management of inflammatory illnesses. More research on Berberine and related flavonoids is necessary to assess its safety. As a result, Berberine can be regarded as a candidate for the advancement of an immunomodulatory agent

Pathological Computed Tomography Features Associated with Adverse Outcomes after Mild Traumatic Brain Injury:A TRACK-TBI Study with External Validation in CENTER-TBI

Importance: A head computed tomography (CT) with positive results for acute intracranial hemorrhage is the gold-standard diagnostic biomarker for acute traumatic brain injury (TBI). In moderate to severe TBI (Glasgow Coma Scale [GCS] scores 3-12), some CT features have been shown to be associated with outcomes. In mild TBI (mTBI; GCS scores 13-15), distribution and co-occurrence of pathological CT features and their prognostic importance are not well understood. Objective: To identify pathological CT features associated with adverse outcomes after mTBI. Design, Setting, and Participants: The longitudinal, observational Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) study enrolled patients with TBI, including those 17 years and older with GCS scores of 13 to 15 who presented to emergency departments at 18 US level 1 trauma centers between February 26, 2014, and August 8, 2018, and underwent head CT imaging within 24 hours of TBI. Evaluations of CT imaging used TBI Common Data Elements. Glasgow Outcome Scale-Extended (GOSE) scores were assessed at 2 weeks and 3, 6, and 12 months postinjury. External validation of results was performed via the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) study. Data analyses were completed from February 2020 to February 2021. Exposures: Acute nonpenetrating head trauma. Main Outcomes and Measures: Frequency, co-occurrence, and clustering of CT features; incomplete recovery (GOSE scores <8 vs 8); and an unfavorable outcome (GOSE scores <5 vs ≥5) at 2 weeks and 3, 6, and 12 months. Results: In 1935 patients with mTBI (mean [SD] age, 41.5 [17.6] years; 1286 men [66.5%]) in the TRACK-TBI cohort and 2594 patients with mTBI (mean [SD] age, 51.8 [20.3] years; 1658 men [63.9%]) in an external validation cohort, hierarchical cluster analysis identified 3 major clusters of CT features: contusion, subarachnoid hemorrhage, and/or subdural hematoma; intraventricular and/or petechial hemorrhage; and epidural hematoma. Contusion, subarachnoid hemorrhage, and/or subdural hematoma features were associated with incomplete recovery (odds ratios [ORs] for GOSE scores <8 at 1 year: TRACK-TBI, 1.80 [95% CI, 1.39-2.33]; CENTER-TBI, 2.73 [95% CI, 2.18-3.41]) and greater degrees of unfavorable outcomes (ORs for GOSE scores <5 at 1 year: TRACK-TBI, 3.23 [95% CI, 1.59-6.58]; CENTER-TBI, 1.68 [95% CI, 1.13-2.49]) out to 12 months after injury, but epidural hematoma was not. Intraventricular and/or petechial hemorrhage was associated with greater degrees of unfavorable outcomes up to 12 months after injury (eg, OR for GOSE scores <5 at 1 year in TRACK-TBI: 3.47 [95% CI, 1.66-7.26]). Some CT features were more strongly associated with outcomes than previously validated variables (eg, ORs for GOSE scores <5 at 1 year in TRACK-TBI: neuropsychiatric history, 1.43 [95% CI.98-2.10] vs contusion, subarachnoid hemorrhage, and/or subdural hematoma, 3.23 [95% CI 1.59-6.58]). Findings were externally validated in 2594 patients with mTBI enrolled in the CENTER-TBI study. Conclusions and Relevance: In this study, pathological CT features carried different prognostic implications after mTBI to 1 year postinjury. Some patterns of injury were associated with worse outcomes than others. These results support that patients with mTBI and these CT features need TBI-specific education and systematic follow-up

Clinical predictors of 3- and 6-month outcome for mild traumatic brain injury patients with a negative head CT scan in the emergency department: A TRACK-TBI pilot study

Aconsiderable subset of mild traumatic brain injury (mTBI) patients fail to return to baseline functional status at or beyond 3 months postinjury. Identifying at-risk patients for poor outcome in the emergency department (ED) may improve surveillance strategies and referral to care. Subjects with mTBI (Glasgow Coma Scale 13–15) and negative ED initial head CT < 24 h of injury, completing 3- or 6-month functional outcome (Glasgow Outcome Scale-Extended; GOSE), were extracted from the prospective, multicenter Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) Pilot study. Outcomes were dichotomized to full recovery (GOSE = 8) vs functional deficits (GOSE < 8). Univariate predictors with p < 0.10 were considered for multivariable regression. Adjusted odds ratios (AOR) were reported for outcome predictors. Significance was assessed at p < 0.05. Subjects who completed GOSE at 3- and 6-month were 211 (GOSE < 8: 60%) and 185 (GOSE < 8: 65%). Risk factors for 6-month GOSE < 8 included less education (AOR = 0.85 per-year increase, 95% CI: (0.74–0.98)), prior psychiatric history (AOR = 3.75 (1.73–8.12)), Asian/minority race (American Indian/Alaskan/Hawaiian/Pacific Islander) (AOR = 23.99 (2.93–196.84)), and Hispanic ethnicity (AOR = 3.48 (1.29–9.37)). Risk factors for 3-month GOSE < 8 were similar with the addition of injury by assault predicting poorer outcome (AOR = 3.53 (1.17–10.63)). In mTBI patients seen in urban trauma center EDs with negative CT, education, injury by assault, Asian/minority race, and prior psychiatric history emerged as risk factors for prolonged disability

A Global Building Occupant Behavior Database

This paper introduces a database of 34 field-measured building occupant behavior datasets collected from 15 countries and 39 institutions across 10 climatic zones covering various building types in both commercial and residential sectors. This is a comprehensive global database about building occupant behavior. The database includes occupancy patterns (i.e., presence and people count) and occupant behaviors (i.e., interactions with devices, equipment, and technical systems in buildings). Brick schema models were developed to represent sensor and room metadata information. The database is publicly available, and a website was created for the public to access, query, and download specific datasets or the whole database interactively. The database can help to advance the knowledge and understanding of realistic occupancy patterns and human-building interactions with building systems (e.g., light switching, set-point changes on thermostats, fans on/off, etc.) and envelopes (e.g., window opening/closing). With these more realistic inputs of occupants’ schedules and their interactions with buildings and systems, building designers, energy modelers, and consultants can improve the accuracy of building energy simulation and building load forecasting