50 research outputs found

    DESIGN AND ANALYSIS OF THREE-PHASE SPLIT SOURCE INVERTER

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    In many DC-AC power conversions a voltage source inverter (VSI) along with an additional DC-DC boosting stage is required. To overcome this problem in VSI, a split source inverter is preferred. This paper presents a combination of boost stage and VSI stage as a single unit DC-AC power conversion named as split source inverter (SSI). The proposed topology require three additional diodes with same number of active switches of VSI and eight same states of conventional pulse width modulation. This work present the analysis of SSI with sinusoidal pulse width modulation technique. The developed SSI model is simulated on MATLAB/SIMULINK environment. Simulation results have been obtained for inverter voltage, inductor current, output line current and total harmonic distortion of output line current

    Comments on the Refractive Index of Tin Sulphide Nano-crystalline Thin Films

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    The refractive indices of nano-crystalline thin films of Tin (IV) Sulphide (SnS) were investigated here. The experimental data conformed well with the single oscillator model for refractive indices. Based on the this, we explain the increasing trend of refractive index to the improvement in crystal ordering with increasing grain size.Comment: Nine figure

    Significance of evaluating mandibular parameters for the identification of an individual

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    Background: Estimating the age of death is a crucial step since it narrows the field of probable identities that must be compared to remains after mass tragedies. Morphological changes in the mandible are mostly driven by an individual’s age and occlusal status. The aim of this study was to determine the association of the dimensions of these parameters with the age and gender of an individual with a larger sample size using orthopantograms in the north Indian population. Methods: A retrospective radio morphometric analysis was performed for panoramic radiographs of 300 (150 males and 150 females). The digital panoramic images were saved in Dicom format and exported to MicroDicom software for linear measurements. The co-relation of study parameters with age was analyzed by one-way ANOVA and assessment of co-relation with sex by applying student’s t-test. Results: The mean values of the right and left gonial angles were higher in females, while the ramus height and bigonial width dimensions were greater in males. However, only the left gonial angle and ramus height showed statistically significant differences with gender (p<0.05). Conclusions: The present study found substantial changes in gonial angle, ramus height, and bigonial breadth based on gender and age in a larger sample size. As a result, these dimensions can be an accurate predictor of an individual’s age and sex. Thus, morphometric examination of the mandible can be a useful tool in both identifying individuals and studying growth patterns

    ASSOCIATION AND CORRELATION OF MEAN PLATELET VOLUME AND PLATELET COUNT IN ACUTE ISCHEMIC STROKE

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    Objective: Role of platelets in the pathogenesis of the atherothrombosis and ischemic stroke has been documented. Mean platelet volume (MPV) and platelet count (PC) could be important predictors of acute ischemic stroke (AIS), its severity; therefore we investigated the correlation of MPV & PC in AIS patients. Methods: We studied MPV and PC of 52 AIS patients consecutively admitted in Neurology department at Geetanjali Medical University, India. Platelet variables were measured and compared with control of similar age, sex and without vascular events. Results: Out of 52 patients, 30 (57.69%) had Thirty (57.69%) patients had significantly higher MPV in AIS group (12.45fL compared with normal range of 6–11 fL in control,p<0.001). No significant differences were found between male and females, but the total mean was elevated. The mean of PC was 1.76×105 cells/cumm (normal range) and there was no correlation between the change in PC and AIS in both sexes. Repeated measurements of MPV and PC were also recorded on follow-up which showed no significant changes from the acute phase; however, MPV remained elevated. The comparison of MPV in patients with mRS score 2 versus 4, 2 versus 5, 3 versus 4 and 5, and 4 versus 5 were found to be statistically significant (p<0.05). Conclusion: Increased MPV has an independent association with AIS and its severity and it could not change after acute treatment. It is possible that these changes precede the vascular event, and further studies are warranted to unravel the underlying mechanism

    MELATONIN AMELIORATES FLUORIDE INDUCED NEUROTOXICITY IN YOUNG RATS: AN IN VIVO EVIDENCE

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    Objective: Developing brain is highly vulnerable to environmental toxins. Recently, fluoride was declared as a developmental neurotoxin and heralded search for natural neuroprotectant. In the present study, we have evaluated the neuroprotective and anti-inflammatory efficacy of melatonin in fluoride induced neurotoxicity.Methods: Animals were divided into following groups; the first group was used as control. Groups 2, 3 and 4 were treated with melatonin (10 mg/kg BW), sodium fluoride (NaF 4 mg/kg BW) and NaF (4 mg/kg BW) plus melatonin (10 mg/kg BW) respectively. Young rats were orally administered their respective doses daily for 60 days. Biochemical and behavioral analysis were performed. The level of proinflammatory cytokine, tumor necrosis factor alpha (TNF-a) was also determined.Results: Data obtained showed that NaF significantly (p<0.001) increased thiobarbituric acid reactive substances (TBARS), ROS concentration and decreased the activities of glutathione (GSH) and glutathione peroxidase (GPx). On the other hand, melatonin plus NaF treated group showed significant decrease in the levels of TBARS and ROS while it increased the activities of antioxidant enzymes and glutathione content. In addition, melatonin significantly attenuated fluoride-induced increase in the TNF-α level of brain. Melatonin also prevented the cognitive deficit as shown by the increased retention latency in the passive avoidance task (p<0.001).Conclusion: The present study suggests that melatonin has therapeutic potential since it suppresses fluoride induced inflammation, cognitive impairment and oxidative stress in the brain. Key words: Oxidative stress, Inflammation, Melatonin, TNF- α, Fluoride

    A STUDY OF SEVERITY OF STROKE AND HOMOCYSTEINE LEVEL IN SOUTHERN PART OF RAJASTHAN, INDIA

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    Objective: Till date, a very few prospective studies have examined the association between serum homocysteine levels and the risk of stroke and stroke subtypes in Indian populations. Methods: A prospective, case - control study of Indian subjects 10–90 years of age was conducted using frozen serum samples from 103 participants in cardiovascular risk surveys collected from December 2017 to November 2018. By the end of 103, we identified 55 incidents of severe strokes, one control subject per case was selected by matching for sex, age, community, year of serum storage, and fasting status. Serum total homocysteine levels were measured by Cobas c-311. Results: Compared with control subjects, total (n_206), hemorrhagic (n_106), and ischemic (n_87) strokes had higher geometric mean values of total homocysteine and higher proportions of homocysteine −25.0 μ mol/L. Homocysteine was estimated after adjustment for body mass index, smoking, alcohol intake, hypertension, and other cardiovascular risk factors. The excess risk of total and ischemic strokes did not vary significantly according to sex, age, smoking status, or hypertensive status. Conclusion: High total homocysteine concentrations were associated with the increased risk of total stroke, more specifically ischemic stroke) Capsuloganglionic and frontoparietal infarct (8 each)., among Indian men and women

    Incidentally Detected Squamous Cell Carcinoma of Renal Pelvis in Patients with Staghorn Calculi: Case Series with Review of the Literature

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    Squamous cell carcinoma of the renal pelvis is a rare neoplasm, often unsuspected clinically due to its rarity and ambiguous clinical and radiological features, and hence patients present at advanced stages resulting in poor prognosis. We report here four cases of incidentally diagnosed primary renal squamous cell carcinoma, treated at our hospital over a short span of one year, and review the relevant literature. Mean age of the patients (3 males, 1 female) was 60 years. All suffered from staghorn stones. Interestingly, renal carcinoma was unsuspected clinically in all patients. In one case, a computerised tomography scan showed a suspicious nodule. All underwent nephrectomy for nonfunctioning kidney. In just two cases, tumor was identified on gross examination, while the other two only showed thickened pelvis. Our series emphasises the need for pelvicalyceal biopsy during treatment for long-standing nephrolithiasis, and thorough sampling of the renal pelvis in nephrectomy specimen of such patients

    A COMPARATIVE EVALUATION OF ANTIMICROBIAL EFFICACY OF MAJUPHALLA INCORPORATED ZINC OXIDE WITH OZONE OIL AND ZINC OXIDE EUGENOL AS AN OBTURATING MATERIALS IN PRIMARY TEETH AGAINST ENTEROCOCCUS FAECALIS AND CANDIDA ALBICANS”- AN IN-VITRO STUDY

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    Preservation of primary tooth with non-vital pulp is a major concern for a Pediatric dentist, for which the preferred treatment modality is to perform pulpectomy. The objective of pulpectomy is the complete removal of necrotic and irreversibly infected pulp of an affected tooth but, despite chemo mechanical preparation and copious irrigation of the canal, failure of pulp therapy occurs due to entrapped micro-organisms in canal space. Thus, for optimal success obturating material with antimicrobial properties is advocated for obturation. Aim The study aimed to assess the antimicrobial efficacy of majuphalla incorporated zinc oxide with ozone oil and zinc oxide eugenol as an obturating material against E. faecalis and Candida albicans. Materials and Methods The present study compared the antimicrobial efficacy of zinc oxide mixed with majuphalla powder and ozone oil as the study group and zinc oxide eugenol as a control group. Antimicrobial efficacy was evaluated against E. faecalis and Candida albicans. Statistical analysis was done using SPSS 21.0 version, IBM, Chicago, inter-group comparison of continuous variables was done using One-way ANOVA, and Intra-group comparison of continuous variables was done using repeated measures ANOVA. Results Intergroup comparison at 24 hours ,15th day and 30th day revealed significant difference amongst both groups. Zinc oxide and majuphalla with ozone oil had significantly higher zone of inhibition as compared to ZOE group against E. faecalis and Candida albicans. Conclusion Antimicrobial activity of Zinc oxide with majuphalla and ozone oil is more than zinc oxide eugenol for both E. faecalis and Candida albican

    Implementation of Automated Training & Placement

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    Training and placement is the crucial part of any educational institutes in which most of the work till now is being done manually. The aim of this project is that automation of training and placement department that will include minimum manual work and maximum optimization abstraction security. This is the web application as well as mobile application which can use in the android operating system as well as IOS operating system it is developed in ionic framework[1]. Students need to register in this application by filling all basic details like email_id, enrollment number etc. After successful registration students can able to logged into the system and after login he/she need to update his/her profile[4]. Also in this students can able to view company details. The training and placement department contains all the information about the students. The system stores all the personal information of the students like their personal details, qualification details and academic details. Also Admin can able to update the company details. In this project student get the notifications about the companies coming for the campus via SMS and email listing out the students as per company?s criteria provides all the details of the interview[8]. This project reduces the human efforts and maintaining large amount of data properly
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