Are Rapid Population Estimates Accurate? A Field Trial of Two Different Assessment Methods.

Emergencies resulting in large-scale displacement often lead to populations resettling in areas where basic health services and sanitation are unavailable. To plan relief-related activities quickly, rapid population size estimates are needed. The currently recommended Quadrat method estimates total population by extrapolating the average population size living in square blocks of known area to the total site surface. An alternative approach, the T-Square, provides a population estimate based on analysis of the spatial distribution of housing units taken throughout a site. We field tested both methods and validated the results against a census in Esturro Bairro, Beira, Mozambique. Compared to the census (population: 9,479), the T-Square yielded a better population estimate (9,523) than the Quadrat method (7,681; 95% confidence interval: 6,160-9,201), but was more difficult for field survey teams to implement. Although applicable only to similar sites, several general conclusions can be drawn for emergency planning

A new Manifestation of Atomic Parity Violation in Cesium: a Chiral Optical Gain induced by linearly polarized 6S-7S Excitation

We have detected, by using stimulated emission, an Atomic Parity Violation (APV) in the form of a chiral optical gain of a cesium vapor on the 7S - 6P$_{3/2}$ transition,consecutive to linearly polarized 6S-7S excitation. We demonstrate the validity of this detection method of APV, by presenting a 9% accurate measurement of expected sign and magnitude. We underline several advantages of this entirely new approach in which the cylindrical symmetry of the set-up can be fully exploited. Future measurements at the percent level will provide an important cross-check of an existing more precise result obtained by a different method.Comment: 4 pages, 2 figure

Search for anisotropic effects of hcp solid helium on optical lines of cesium impurities

The anisotropic effect of a hcp 4He solid matrix on cesium atoms has been proposed as a tool to reveal the parity violating anapole moment of its nucleus. It should also result in splitting the D2 optical excitation line in a way depending on the light polarization. An experimental investigation has been set up using oriented hcp helium crystals in which cesium metal grains are embedded. Atoms are created by laser sputtering from this grains. Optical absorption spectra of the D2 line have been recorded in the temperature range of 1.0 to 1.4 K at liquid/solid coexistence pressure by monitoring the fluorescence on the D2 line at 950 nm. No significant effect of the light polarization has been found, suggesting a statistically isotropic disordered solid environment for the cesium atoms.Comment: The original publication will be available at http://www.springerlink.co

Erratum to: Comparative assessment of image quality for coronary CT angiography with iobitridol and two contrast agents with higher iodine concentrations: iopromide and iomeprol. A multicentre randomized double-blind trial

Unfortunately, there is amistake in the section Results, Clinical safety. While the text states that “no severe AEs were reported”, in fact one severe AE was reported in the iomeprol group (one severe injection site pain assessed as possibly related to contrast agent), as shown in Table 5. In addition, the name of the author Jean-François Paul was rendered incorrectly in the original publication but has since been corrected. The authors apologize for these mistakes

Charcot-Marie-Tooth disease type 2CC due to NEFH variants causes a progressive, non-length-dependent, motor-predominant phenotype

Objective: Neurofilaments are the major scaffolding proteins for the neuronal cytoskeleton, and variants in NEFH have recently been described to cause axonal Charcot-Marie-Tooth disease type 2CC (CMT2CC). Methods: In this large observational study, we present phenotype–genotype correlations on 30 affected and 3 asymptomatic mutation carriers from eight families. Results: The majority of patients presented in adulthood with motor-predominant and lower limb-predominant symptoms and the average age of onset was 31.0±15.1 years. A prominent feature was the development of proximal weakness early in the course of the disease. The disease progressed rapidly, unlike other Charcot-Marie-Tooth disease (CMT) subtypes, and half of the patients (53%) needed to use a wheelchair on average 24.1 years after symptom onset. Furthermore, 40% of patients had evidence of early ankle plantarflexion weakness, a feature which is observed in only a handful of CMT subtypes. Neurophysiological studies and MRI of the lower limbs confirmed the presence of a non-length-dependent neuropathy in the majority of patients. All families harboured heterozygous frameshift variants in the last exon of NEFH, resulting in a reading frameshift to an alternate open reading frame and the translation of approximately 42 additional amino acids from the 3' untranslated region (3′-UTR). Conclusions: This phenotype–genotype study highlights the unusual phenotype of CMT2CC, which is more akin to spinal muscular atrophy rather than classic CMT. Furthermore, the study will enable more informative discussions on the natural history of the disease and will aid in NEFH variant interpretation in the context of the disease’s unique molecular genetics

Rapport final du projet européen CatClay sur les processus de migration des cations dans les roches argileuses indurées

International audienceIn the framework of the feasibility studies on the radioactive waste disposal in deep argillaceous formations, it isnow well established that the transport properties of solutes in clay rocks, i.e. parameter values for Fick’s law, are mainlygoverned by the negatively charged clay mineral surface. While a good understanding of the diffusive behaviour of non-reactiveanionic and neutral species is now achieved, much effort has to be placed on improving understanding of coupledsorption/diffusion phenomena for sorbing cations. Indeed, several cations known to form highly stable surface complexes withsites on mineral surfaces migrate more deeply into clay rock than expected. Therefore, the overall objective of the EC CatClayproject is to address this issue, using a ‘bottom-up’ approach, in which simpler, analogous systems (here a compacted clay,‘pure’ illite) are experimentally studied and modelled, and then the transferability of these results to more complex materials, i.e.the clay rocks under consideration in France, Switzerland and Belgium for hosting radioactive waste disposal facilities, isverified. The cations of interest were chosen for covering a representative range of cations families: from a moderately sorbingcation, the strontium, to three strongly sorbing cations, Co(II), Zn(II) and Eu(III). For the 4 years of this project, much effort wasdevoted to developing and applying specific experimental methods needed for acquiring the high precision, reliable data neededto test the alternative hypotheses represented by different conceptual-numerical models. The enhanced diffusion of the sorbingcations of interest was confirmed both in the simpler analogous illite system for Sr2+, Co(II) and Zn(II), but also in the naturalclay rocks, except for Eu(III). First modelling approach including diffusion in the diffuse double layer (DDL) promisinglysucceeded in reproducing the experimental data under the various conditions both in illite and clay rocks, even though someassumptions made have to be verified. In parallel, actual 3D geometrical pore size distributions of compacted illite, and in lessextent, clay rock samples, were successfully determined by combining TEM and FIB-nt analyses on materials maintained in awater-like saturation state by means of an extensive impregnation step. Based on this spatial distribution of pores, first numericaldiffusion experiments were carried at the pore scale through virtual illite, enabling a better understanding of how transferpathways are organized in the porous media. Finally, the EC CatClay project allowed a better understanding of the migration ofstrongly sorbing tracers through low permeability ‘clay rock’ formations, increasing confidence in our capacity to demonstratethat the models used to predict radionuclide migration through these rocks are scientifically sound

Using Markov chain Monte Carlo methods for estimating parameters with gravitational radiation data

We present a Bayesian approach to the problem of determining parameters for coalescing binary systems observed with laser interferometric detectors. By applying a Markov Chain Monte Carlo (MCMC) algorithm, specifically the Gibbs sampler, we demonstrate the potential that MCMC techniques may hold for the computation of posterior distributions of parameters of the binary system that created the gravity radiation signal. We describe the use of the Gibbs sampler method, and present examples whereby signals are detected and analyzed from within noisy data.Comment: 21 pages, 10 figure

Status, scientific results and technical improvements of the NBH on TCV tokamak

The TCV tokamak contributes to physics understanding in fusion reactor research by a wide set of experimental tools, like flexible shaping and high power ECRH. A 1MW, 25 keV deuterium heating neutral beam (NB) has been installed in 2015 and it was operated from 2016 in SPC-TCV domestic and EUROfusion MST1 experimental campaigns ((similar to)50/50%). The rate of failures of the beam is less than 5%. Ion temperatures up to 3.5 keV have been achieved in ELMy H-mode, with a good agreement with ASTRA predictive simulations. The NB enables TCV to access ITER-like beta(N) values (1.8) and T-e/T-i (similar to)1, allowing investigations of innovative plasma features in ITER relevant ELMy H-mode. The advanced Tokamak route was also pursued, with stationary, fully non-inductive discharges sustained by ECCD and NBCD reaching beta(similar to)(N)1.4-1.7. Real-time control of the NB power has been implemented in 2018 and presented together with the statistics of NB operation on the TCV. During commissioning, the NB showed unacceptable heating of the TCV beam duct, indicating a higher power deposition than expected on duct walls. A high beam divergence has been found by dedicated measurement of 3-D beam power density distribution with an expressly designed device (IR measurement on tungsten target)