Стилистический эффект разговорной речи и его составляющие

В обучении русскому языку как иностранному на современном этапе большое внимание уделяется особенностям русской разговорной речи. Это обусловлено целым рядом причин, среди которых, на наш взгляд, можно выделить следующие: во-первых, разговорная речь всегда отличается активностью проникновения во все сферы жизнедеятельности людей и функционирует как в повседневном общении, так и в различных сферах (литературе, кино, политике и т.д.). Во-вторых, разговорная речь носит многожанровый характер, что зачастую затрудняет ее понимание иностранными студентами. В-третьих, в разговорную речь помимо слов нейтрального стиля все активнее стала проникать арготическая лексика. Именно в связи с этим особый интерес у нас вызывает разговорный стиль речи в преломлении на инофонную аудиторию

Alternate reading frame-encoded amino acids in circulating viral sequences.

<p>A) Distribution of known mutant origins across viral ARF sequences attributable to a particular cause based on information associated with the sequence accession the NCBI nr protein database presented in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0039311#pone.0039311.s002" target="_blank">Table S2</a>. B) Composition of viral coding sequence computed as a percentage assigned to the coding sequence for the Env, Gag, Pol poly-proteins based on nucleotide base counts for a particular gene region compared to the total nucleotide count for the structural genes of the virus. Gag comprises 1,503 nt of the total of 6,878 nt of structural gene sequence; Pol comprises 3,139 nt of the total; Env comprises of 2,571 nt of the total. This is the distribution of origins within the genome that would be expected if originating events for the incorporation of ARF and their detection in circulating HIV-1 viral sequences were distributed randomly throughout the genome. C) The distribution of ARF incorporated into circulating viral sequences that was observed in our searches of NCBI nr protein database for ARF sequences in circulating HIV-1 viral sequences. The percentages were computed by dividing the number of BLAST hits with ARF sequence incorporated into a given gene region by the 123 total hits examined. D) A three-way alignment between the HXB-2 reference sequence for the Env region, the accession AAL78125.1 and the alternate reading frame encoded ORF 67. E) A three-way alignment between the HXB-2 reference sequence for the Gag region, the accession AEQ21252.1 and the alternate reading frame encoded ORF 3. F) A three-way alignment between the HXB-2 reference sequence for the Pol region, the accession CAF29000.1 and the alternate reading frame encoded ORF 23. All three-way alignments were generated by combining two pair-wise alignments created in Geneious, followed by manual editing. Note each accession is similar to both the HXB-2 reference sequence for the structural proteins and the alternate reading frame encoded sequence, but not to both sequences simultaneously within the same region of the sequence.</p

Patients’ characteristics.

<p>Table depicts whether patients were HIV-1 acutely or chronically infected, stage of treatment, the number of patients used in the study, the number of extra patients included in the study, total number of samples tested, mean frequency of CD4⁺ and CD8⁺ T cells (cells/µL) and viral load (copies/mL).</p

Breadth of ARF responses in chronically infected patients.

<p>A) Number of detectable responses observed for each individual ARF peptide-pool tested. B) Number of ARF peptide pools that induced detectable responses in each chronically infected individual. Grey bars represent patients Before HAART and black bars represent patients On HAART. Patients #47 and #48 were only tested before HAART introduction and patient #49 was only tested after HAART.</p

HIV-1 genome (HXB-2 strain), and localization of the 47 alternative reading frames (ARF).

<p>Figure depicts all 199 ARF-tested peptides. These include 13 forward ARF within frames 1, 2 or 3 (in green) and 34 reverse ARF within frames -1, -2 or -3 (in purple). HIV-1 classically defined encoding genes are shown in blue.</p

ARF responses in one HIV-1 chronically infected patients before and on HAART.

<p>In the pie charts each color represents a pool of immune response that the patient mounted against. Numbers inside the pie charts correspond to the magnitude of the response against the pool in SFU/million PBMC.</p

Breadth of ARF responses in acutely infected patients.

<p>A) Number of detectable responses observed for each individual ARF peptide-pool tested. B) Number of ARF peptide pools that induced detectable responses in each acutely infected individual. Blue bars represent patients On HAART and red bars represent patients Off HAART. We were unable to follow patients #26, #27 and #28 before HAART interruption.</p