1,213 research outputs found

    Availability of Information on Reptile Health and Welfare from Stores Selling Reptiles

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    This is the final version of the article. It first appeared from Scientific Research via http://dx.doi.org/10.4236/ojvm.2016.63007The popularity of keeping reptiles such as snakes and lizards is ever increasing. The health and welfare of these animals depends on the knowledge and understanding of their environmental and nutritional needs. But where does a new owner of these species obtain such information? This study aims to investigate what information is available in pet shops and stores for the reptile owning public and how well this information is imparted. Our findings show that there is a lot of excellent advice on the husbandry of reptiles in some shops while others offer less advice. It is hoped that through this study areas of downfall on primary knowledge can be recognized so that all shops can aspire to the highest levels of information

    Reverse-engineering the cortical architecture for controlled semantic cognition.

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    We employ a reverse-engineering approach to illuminate the neurocomputational building blocks that combine to support controlled semantic cognition: the storage and context-appropriate use of conceptual knowledge. By systematically varying the structure of a computational model and assessing the functional consequences, we identified the architectural properties that best promote some core functions of the semantic system. Semantic cognition presents a challenging test case, as the brain must achieve two seemingly contradictory functions: abstracting context-invariant conceptual representations across time and modalities, while producing specific context-sensitive behaviours appropriate for the immediate task. These functions were best achieved in models possessing a single, deep multimodal hub with sparse connections from modality-specific regions, and control systems acting on peripheral rather than deep network layers. The reverse-engineered model provides a unifying account of core findings in the cognitive neuroscience of controlled semantic cognition, including evidence from anatomy, neuropsychology and functional brain imaging

    Overlapping Neural Correlates Underpin Theory of Mind and Semantic Cognition:Evidence from a Meta-Analysis of 344 Functional Neuroimaging Studies

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    Key unanswered questions for cognitive neuroscience include whether social cognition is underpinned by specialised brain regions, and to what extent it simultaneously depends on more domain-general systems. Until we glean a better understanding of the contribution made by domain-general cognitive systems, theories of social cognition will remain fundamentally limited. In the present study, we evaluate a recent and novel proposal that the semantic cognition network plays a crucial role in supporting social processes. We specifically focus on theory of mind (ToM) abilities and adopt a meta-analytic activation likelihood estimation approach to synthesise the results of a large set of functional neuroimaging studies. Our primary aim was to establish the degree of topological overlap between the cortical networks involved in ToM and semantic tasks. Moreover, we sought to account for key methodological differences across the two sets of tasks, including the fact that ToM studies tend to use nonverbal stimuli while the semantics literature is dominated by language-based tasks. We observed extensive overlap between the two networks in regions strongly implicated in semantic cognition, including the anterior temporal lobes and the left temporoparietal junction (TPJ). Activation specific to ToM was identified in the right TPJ, bilateral anterior mPFC, and right precuneus. These findings persisted even after controlling for discrepancies in the types of experimental stimuli used in each domain. Overall, the findings support the claim that ToM draws upon more general semantic retrieval processes and are against the view that ToM is underpinned solely by a domain-specific social neurocognitive system

    The graded change in connectivity across the ventromedial prefrontal cortex reveals distinct subregions

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    The functional heterogeneity of the ventromedial prefrontal cortex (vmPFC) suggests it may include distinct functional subregions. To date these have not been well elucidated. Regions with differentiable connectivity (and as a result likely dissociable functions) may be identified using emergent data-driven approaches. However, prior parcellations of the vmPFC have only considered hard splits between distinct regions, although both hard and graded connectivity changes may exist. Here we determine the full pattern of change in structural and functional connectivity across the vmPFC for the first time and extract core distinct regions. Both structural and functional connectivity varied along a dorsomedial to ventrolateral axis from relatively dorsal medial wall regions to relatively lateral basal orbitofrontal cortex. The pattern of connectivity shifted from default mode network to sensorimotor and multimodal semantic connections. This finding extends the classical distinction between primate medial and orbital regions by demonstrating a similar gradient in humans for the first time. Additionally, core distinct regions in the medial wall and orbitofrontal cortex were identified that may show greater correspondence to functional differences than prior hard parcellations. The possible functional roles of the orbitofrontal cortex and medial wall are discussed.peer-reviewe

    The Graded Change in Connectivity across the Ventromedial Prefrontal Cortex Reveals Distinct Subregions.

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    The functional heterogeneity of the ventromedial prefrontal cortex (vmPFC) suggests it may include distinct functional subregions. To date these have not been well elucidated. Regions with differentiable connectivity (and as a result likely dissociable functions) may be identified using emergent data-driven approaches. However, prior parcellations of the vmPFC have only considered hard splits between distinct regions, although both hard and graded connectivity changes may exist. Here we determine the full pattern of change in structural and functional connectivity across the vmPFC for the first time and extract core distinct regions. Both structural and functional connectivity varied along a dorsomedial to ventrolateral axis from relatively dorsal medial wall regions to relatively lateral basal orbitofrontal cortex. The pattern of connectivity shifted from default mode network to sensorimotor and multimodal semantic connections. This finding extends the classical distinction between primate medial and orbital regions by demonstrating a similar gradient in humans for the first time. Additionally, core distinct regions in the medial wall and orbitofrontal cortex were identified that may show greater correspondence to functional differences than prior hard parcellations. The possible functional roles of the orbitofrontal cortex and medial wall are discussed.This work was supported by a doctoral prize from the Engineering and Physical Sciences Research Council and a British Academy Postdoctoral Fellowship (pf170068) to RLJ, a studentship from the BBSRC (BB/J014478/1) to CJB, and programme grants from the Medical Research Council (MR/J004146/1 & MR/R023883/1) to MALR
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