36 research outputs found
Strategies in 'snake venomics' aiming at an integrative view of compositional, functional, and immunological characteristics of venoms
This work offers a general overview on the evolving strategies for the proteomic analysis of snake venoms, and
discusses how these may be combined through diverse experimental approaches with the goal of achieving a
more comprehensive knowledge on the compositional, toxic, and immunological characteristics of venoms.
Some recent developments in this field are summarized, highlighting how strategies have evolved from the mere
cataloguing of venom components (proteomics/venomics), to a broader exploration of their immunological
(antivenomics) and functional (toxicovenomics) characteristics. Altogether, the combination of these complementary
strategies is helping to build a wider, more integrative view of the life-threatening protein cocktails produced by
venomous snakes, responsible for thousands of deaths every year.Ministerio de Economía y Competitividad/[BFU2013-42833-P]//EspañaUCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias de la Salud::Instituto Clodomiro Picado (ICP