The Effect of Hippotherapy on Sitting Balance in Children with Cerebral Palsy

Hippotherapy programs have grown rapidly since 1969, when the first center opened in the United States. Despite the growing enthusiasm for hippotherapy in North America, research regarding the efficacy of hippotherapy is not well documented. Literature that pertains to the therapeutic benefits of hippotherapy consists primarily of descriptive articles containing subjective reports of riding instructors, riders, parents, and therapists. Hippotherapy is proposed to develop neuromuscular control, facilitate posture, elicit righting and equilibrium reactions, provide vestibular input, and improve psychological wellbeing. While these descriptive articles have identified variables to be empirically studied, few investigators have documented the therapeutic effects of hippotherapy. The purpose of this study is to determine if there is a significant improvement in the sitting balance of children with cerebral palsy (CP) after sessions of hippotherapy. Six children participated in a six-week study, undergoing assessment with a repeated measures design. Results indicated that sitting balance was not significantly improved. Further study is needed to establish the effectiveness of hippotherapy

Creating Full Individual-level Location Timelines from Sparse Social Media Data

In many domain applications, a continuous timeline of human locations is critical; for example for understanding possible locations where a disease may spread, or the flow of traffic. While data sources such as GPS trackers or Call Data Records are temporally-rich, they are expensive, often not publicly available or garnered only in select locations, restricting their wide use. Conversely, geo-located social media data are publicly and freely available, but present challenges especially for full timeline inference due to their sparse nature. We propose a stochastic framework, Intermediate Location Computing (ILC) which uses prior knowledge about human mobility patterns to predict every missing location from an individual's social media timeline. We compare ILC with a state-of-the-art RNN baseline as well as methods that are optimized for next-location prediction only. For three major cities, ILC predicts the top 1 location for all missing locations in a timeline, at 1 and 2-hour resolution, with up to 77.2% accuracy (up to 6% better accuracy than all compared methods). Specifically, ILC also outperforms the RNN in settings of low data; both cases of very small number of users (under 50), as well as settings with more users, but with sparser timelines. In general, the RNN model needs a higher number of users to achieve the same performance as ILC. Overall, this work illustrates the tradeoff between prior knowledge of heuristics and more data, for an important societal problem of filling in entire timelines using freely available, but sparse social media data.Comment: 10 pages, 8 figures, 2 table

Psychometric Testing of the Heart Failure Somatic Awareness Scale

Background: Self-management of heart failure relies on patients to assess their symptoms, but their ability to do so is often difficult to determine. The 12-item self-report Heart Failure Somatic Awareness Scale (HFSAS) was developed to measure awareness of and distress secondary to heart failure symptoms. The purpose of this study was to test the psychometric properties of the HFSAS. Methods and Results: Feasibility and discriminant validity of the HFSAS were tested in 49 patients admitted for an exacerbation of heart failure. The HFSAS was acceptable to patients and discriminated between heart failure symptoms and anxiety (r = 0.25, P = .08). When reliability and validity were tested in 201 patients with acute heart failure, theta reliability was adequate (0.71). The HFSAS was low to moderately correlated with general bodily awareness (r = 0.48). No difference was found based on gender, but younger patients had higher mean and median HFSAS scores (more distress). The HFSAS was a significant predictor of symptom duration prior to seeking care for heart failure; higher scores were associated with longer delay before seeking care. Conclusion: The HFSAS is reliable with content, discriminant, and construct validity. Evaluation of its usefulness in teaching patients to monitor daily symptoms is needed

Preliminary comparison of 3.5-cm and 12.6-cm wavelength continuous wave observations of Mars

Radar observations of Mars at Goldstone in 1990 were conducted by transmitting pure sinusoidal signals at 3.5-cm wavelengths and receiving the Doppler-spread echoes from Mars at Earth. Radar transmissions were circularly polarized and the echoes recorded in two senses: depolarized and polarized. Latitudes of the subradar points are between 3.5 deg and 11.1 deg S; longitude coverage is discontinuous. The observed depolarized and polarized echo total cross-sections and their ratios for two wavelengths were compared and discussed

Environmental pollutants from the Scott and Shackleton expeditions during the ‘Heroic Age’ of Antarctic exploration

Early explorers to Antarctica built wooden huts and brought huge quantities of supplies and equipment to support their geographical and scientific studies for several years. When the expeditions ended and relief ships arrived, a rapid exodus frequently allowed only essential items to be taken north. The huts and thousands of items were left behind. Fuel depots with unused containers of petroleum products, asbestos materials, and diverse chemicals were also left at the huts. This investigation found high concentrations of polyaromatic hydrocarbons in soils under and around the historic fuel depots, including anthracene, benzo[b]fluoranthene, benzo[k]fluoranthene, chrysene, fluorene, and pyrene, as well as benzo[a]anthracene, benzo[a]pyrene, and fluoranthene, which are recognized carcinogens. Asbestos materials within the huts have been identified and extensive amounts of fragmented asbestos were found littering the ground around the Cape Evans hut. These materials are continually abraded and fragmented as tourists walk over them and the coarse scoria breaks and grinds down the materials. A chemical spill, within the Cape Evans hut, apparently from caustic substances from one of the scientific experiments, has caused an unusual deterioration and defibration on affected woods. Although these areas are important historic sites protected by international treaties, the hazardous waste materials left by the early explorers should be removed and remedial action taken to restore the site to as pristine a condition as possible. Recommendations are discussed for international efforts to study and clean up these areas, where the earliest environmental pollution in Antarctica was produced

Why We Read Wikipedia

Wikipedia is one of the most popular sites on the Web, with millions of users relying on it to satisfy a broad range of information needs every day. Although it is crucial to understand what exactly these needs are in order to be able to meet them, little is currently known about why users visit Wikipedia. The goal of this paper is to fill this gap by combining a survey of Wikipedia readers with a log-based analysis of user activity. Based on an initial series of user surveys, we build a taxonomy of Wikipedia use cases along several dimensions, capturing users' motivations to visit Wikipedia, the depth of knowledge they are seeking, and their knowledge of the topic of interest prior to visiting Wikipedia. Then, we quantify the prevalence of these use cases via a large-scale user survey conducted on live Wikipedia with almost 30,000 responses. Our analyses highlight the variety of factors driving users to Wikipedia, such as current events, media coverage of a topic, personal curiosity, work or school assignments, or boredom. Finally, we match survey responses to the respondents' digital traces in Wikipedia's server logs, enabling the discovery of behavioral patterns associated with specific use cases. For instance, we observe long and fast-paced page sequences across topics for users who are bored or exploring randomly, whereas those using Wikipedia for work or school spend more time on individual articles focused on topics such as science. Our findings advance our understanding of reader motivations and behavior on Wikipedia and can have implications for developers aiming to improve Wikipedia's user experience, editors striving to cater to their readers' needs, third-party services (such as search engines) providing access to Wikipedia content, and researchers aiming to build tools such as recommendation engines.Comment: Published in WWW'17; v2 fixes caption of Table

Road Extraction From Aerial Video Using Active Contours and Motion Cues

This thesis motivates a fully automatic approach for locating roads in aerial video by using active contours in conjunction with motion cues. Directed active contours provide ideal parametric representations of roads due to their ability to fit the variety seen in road shapes. Motion in stabilized aerial video can be represented as a distribution of spatio-temporal derivatives. These motion cues can then be incorporated into the energy function, which yields active contours that better model the active roads in a scene. We present results using this approach on typical models of both urban and rural scenes

Screening fungi isolated from historic Discovery Hut on Ross Island, Antarctica for cellulose degradation

To survive in Antarctica, early explorers of Antarctica's Heroic Age erected wooden buildings and brought in large quantities of supplies. The introduction of wood and other organic materials may have provided new nutrient sources for fungi that were indigenous to Antarctica or were brought in with the materials. From 30 samples taken from Discovery Hut, 156 filamentous fungi were isolated on selective media. Of these, 108 were screened for hydrolytic activity on carboxymethyl cellulose, of which 29 demonstrated activities. Endo-1, 4-β-glucanase activity was confirmed in the extracellular supernatant from seven isolates when grown at 4°C, and also when they were grown at 15°C. Cladosporium oxysporum and Geomyces sp. were shown to grow on a variety of synthetic cellulose substrates and to use cellulose as a nutrient source at temperate and cold temperatures. The research findings from the present study demonstrate that Antarctic filamentous fungi isolated from a variety of substrates (wood, straw, and food stuffs) are capable of cellulose degradation and can grow well at low temperatures

Detection of lipoarabinomannan (LAM) in urine is an independent predictor of mortality risk in patients receiving treatment for HIV-associated tuberculosis in sub-Saharan Africa: a systematic review and meta-analysis

BackgroundSimple immune capture assays that detect mycobacterial lipoarabinomannan (LAM) antigen in urine are promising new tools for the diagnosis of HIV-associated tuberculosis (HIV-TB). In addition, however, recent prospective cohort studies of patients with HIV-TB have demonstrated associations between LAM in the urine and increased mortality risk during TB treatment, indicating an additional utility of urinary LAM as a prognostic marker. We conducted a systematic review and meta-analysis to summarise the evidence concerning the strength of this relationship in adults with HIV-TB in sub-Saharan Africa, thereby quantifying the assay’s prognostic value.MethodsWe searched MEDLINE and Embase databases using comprehensive search terms for ‘HIV’, ‘TB’, ‘LAM’ and ‘sub-Saharan Africa’. Identified studies were reviewed and selected according to predefined criteria.ResultsWe identified 10 studies eligible for inclusion in this systematic review, reporting on a total of 1172 HIV-TB cases. Of these, 512 patients (44%) tested positive for urinary LAM. After a variable duration of follow-up of between 2 and 6months, overall case fatality rates among HIV-TB cases varied between 7% and 53%. Pooled summary estimates generated by random-effects meta-analysis showed a two-fold increased risk of mortality for urinary LAM-positive HIV-TB cases compared to urinary LAM-negative HIV-TB cases (relative risk 2.3, 95% confidence interval 1.6–3.1). Some heterogeneity was explained by study setting and patient population in sub-group analyses. Five studies also reported multivariable analyses of risk factors for mortality, and pooled summary estimates demonstrated over two-fold increased mortality risk (odds ratio 2.5, 95% confidence interval 1.4–4.5) among urinary LAM-positive HIV-TB cases, even after adjustment for other risk factors for mortality, including CD4 cell count.ConclusionsWe have demonstrated that detectable LAM in urine is associated with increased risk of mortality during TB treatment, and that this relationship remains after adjusting for other risk factors for mortality. This may simply be due to a positive test for urinary LAM serving as a marker of higher mycobacterial load and greater disease dissemination and severity. Alternatively, LAM antigen may directly compromise host immune responses through its known immunomodulatory effects. Detectable LAM in the urine is an independent risk factor for mortality among patients receiving treatment for HIV-TB. Further research is warranted to elucidate the underlying mechanisms and to determine whether this vulnerable patient population may benefit from adjunctive interventions.Electronic supplementary materialThe online version of this article (doi:10.1186/s12916-016-0603-9) contains supplementary material, which is available to authorized users