22,034 research outputs found
Bayesian Matrix Completion via Adaptive Relaxed Spectral Regularization
Bayesian matrix completion has been studied based on a low-rank matrix
factorization formulation with promising results. However, little work has been
done on Bayesian matrix completion based on the more direct spectral
regularization formulation. We fill this gap by presenting a novel Bayesian
matrix completion method based on spectral regularization. In order to
circumvent the difficulties of dealing with the orthonormality constraints of
singular vectors, we derive a new equivalent form with relaxed constraints,
which then leads us to design an adaptive version of spectral regularization
feasible for Bayesian inference. Our Bayesian method requires no parameter
tuning and can infer the number of latent factors automatically. Experiments on
synthetic and real datasets demonstrate encouraging results on rank recovery
and collaborative filtering, with notably good results for very sparse
matrices.Comment: Accepted to AAAI 201
Uridylation and adenylation of RNAs.
The posttranscriptional addition of nontemplated nucleotides to the 3' ends of RNA molecules can have a significant impact on their stability and biological function. It has been recently discovered that nontemplated addition of uridine or adenosine to the 3' ends of RNAs occurs in different organisms ranging from algae to humans, and on different kinds of RNAs, such as histone mRNAs, mRNA fragments, U6 snRNA, mature small RNAs and their precursors etc. These modifications may lead to different outcomes, such as increasing RNA decay, promoting or inhibiting RNA processing, or changing RNA activity. Growing pieces of evidence have revealed that such modifications can be RNA sequence-specific and subjected to temporal or spatial regulation in development. RNA tailing and its outcomes have been associated with human diseases such as cancer. Here, we review recent developments in RNA uridylation and adenylation and discuss the future prospects in this research area
Preheating in Bubble Collisions
In a landscape with metastable minima, the bubbles will inevitably nucleate.
We show that during the bubbles collide, due to the dramatically oscillating of
the field at the collision region, the energy deposited in the bubble walls can
be efficiently released by the explosive production of the particles. In this
sense, the collision of bubbles is actually highly inelastic. The cosmological
implications of this result are discussed.Comment: 5 pages, 4 figs, discussion improved, refs. added, and Fig.3 revised,
to publish in PR
- …