Physiological index of strain and body heat storage in hyperthermia /

"Task No. 71830.""Project No. 7164.""January 1961."Includes bibliographical references (page 13).Mode of access: Internet

A direct interaction between the large GTPase dynamin-2 and FAK regulates focal adhesion dynamics in response to active Src

This study establishes Dyn2 as a novel effector downstream of Src-FAK signaling in mediating FA disassembly. FAK directly binds to and recruits Dyn2 to FAs. The formation of a Src–FAK–Dyn2 complex is essential for Dyn2's phosphoactivation and subsequent endocytic turnover of FAs

Behavioral adjustments of a pipefish to bacterial Vibrio challenge

Animals can profit from increasing temperatures by prolonged breeding seasons and faster growth rates. However, these fitness benefits are traded off against higher parasite load and increased virulence of temperature-sensitive pathogens. In thermally stratified habitats, behavioral plasticity can allow hosts to choose the optimal temperature to enhance individual fitness and to escape parasite pressure. To test this idea, we performed a temperature choice experiment with the host-parasite system of the sex-role reversed broad-nosed pipefish (Syngnathus typhle) and its bacterial pathogen Vibrio spp. In this species, pregnant males are expected to face a trade-off between shortening their brooding period in warm water and decreasing the effect of the infection in cold water. We found that exposure to Vibrio changed the temperature preference for both pregnant and nonpregnant males, as well as females compared to nonchallenged fish that tended to prefer warm water. This study shows that behavioral plasticity is one option for avoidance of higher bacterial prevalence, as expected due to rising ocean temperatures