Effects of Limit Feeding a High Concentrate Diet on Feedlot Performance and Carcass Composition of Lambs

Limit feeding high concentrate diets offers several potential benefits to lamb feeders. Limit feeding is one alternative to ad libitum feeding where intake is restricted to an amount which will permit animals to attain some predetermined daily weight gain. This type of feeding system provides a means to reduce day-to-day variations in feed intake, simplifies bunk management, and allows for greater control over feed inventories (Zinn, 1 986) . Using limit feeding to program a particular rate of gain also allows greater marketing flexibility. Restricting intake has been shown to improve the efficiency at which feed is converted into live weight gain in sheep (Glimp et al. , 1989) and cattle (Plegge, 1986) . Reduced average daily gains have been shown to reduce the fat content of empty body weight gains (Turgeon et al. , 1986) . The objectives of this study were to determine the effect of limit feeding a high concentrate diet to achieve three different rates of gain on feedlot performance and body composition of growing lambs

Accreting Protoplanets in the LkCa 15 Transition Disk

Exoplanet detections have revolutionized astronomy, offering new insights into solar system architecture and planet demographics. While nearly 1900 exoplanets have now been discovered and confirmed, none are still in the process of formation. Transition discs, protoplanetary disks with inner clearings best explained by the influence of accreting planets, are natural laboratories for the study of planet formation. Some transition discs show evidence for the presence of young planets in the form of disc asymmetries or infrared sources detected within their clearings, as in the case of LkCa 15. Attempts to observe directly signatures of accretion onto protoplanets have hitherto proven unsuccessful. Here we report adaptive optics observations of LkCa 15 that probe within the disc clearing. With accurate source positions over multiple epochs spanning 2009 - 2015, we infer the presence of multiple companions on Keplerian orbits. We directly detect H{\alpha} emission from the innermost companion, LkCa 15 b, evincing hot (~10,000 K) gas falling deep into the potential well of an accreting protoplanet.Comment: 35 pages, 3 figures, 1 table, 9 extended data item

Real-time estimation and correction of quasi-static aberrations in ground-based high contrast imaging systems with high frame-rates

The success of ground-based, high contrast imaging for the detection of exoplanets in part depends on the ability to differentiate between quasi-static speckles caused by aberrations not corrected by adaptive optics (AO) systems, known as non-common path aberrations (NCPAs), and the planet intensity signal. Frazin (ApJ, 2013) introduced a post-processing algorithm demonstrating that simultaneous millisecond exposures in the science camera and wavefront sensor (WFS) can be used with a statistical inference procedure to determine both the series expanded NCPA coefficients and the planetary signal. We demonstrate, via simulation, that using this algorithm in a closed-loop AO system, real-time estimation and correction of the quasi-static NCPA is possible without separate deformable mirror (DM) probes. Thus the use of this technique allows for the removal of the quasi-static speckles that can be mistaken for planetary signals without the need for new optical hardware, improving the efficiency of ground-based exoplanet detection. In our simulations, we explore the behavior of the Frazin Algorithm (FA) and the dependence of its convergence to an accurate estimate on factors such as Strehl ratio, NCPA strength, and number of algorithm search basis functions. We then apply this knowledge to simulate running the algorithm in real-time in a nearly ideal setting. We then discuss adaptations that can be made to the algorithm to improve its real-time performance, and show their efficacy in simulation. A final simulation tests the technique's resilience against imperfect knowledge of the AO residual phase, motivating an analysis of the feasibility of using this technique in a real closed-loop Extreme AO system such as SCExAO or MagAO-X, in terms of computational complexity and the accuracy of the estimated quasi-static NCPA correction

Adaptive optics for high-resolution imaging

Adaptive optics (AO) is a technique that corrects for optical aberrations. It was originally proposed to correct for the blurring effect of atmospheric turbulence on images in ground-based telescopes and was instrumental in the work that resulted in the Nobel prize-winning discovery of a supermassive compact object at the centre of our galaxy. When AO is used to correct for the eye’s imperfect optics, retinal changes at the cellular level can be detected, allowing us to study the operation of the visual system and to assess ocular health in the microscopic domain. By correcting for sample-induced blur in microscopy, AO has pushed the boundaries of imaging in thick tissue specimens, such as when observing neuronal processes in the brain. In this primer, we focus on the application of AO for high-resolution imaging in astronomy, vision science and microscopy. We begin with an overview of the general principles of AO and its main components, which include methods to measure the aberrations, devices for aberration correction, and how these components are linked in operation. We present results and applications from each field along with reproducibility considerations and limitations. Finally, we discuss future directions

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Low density parasitaemia, red blood cell polymorphisms and Plasmodium falciparum specific immune responses in a low endemic area in northern Tanzania.

BACKGROUND: Low density Plasmodium falciparum infections, below the microscopic detection limit, may play an important role in maintaining malaria transmission in low endemic areas as well as contribute to the maintenance of acquired immunity. Little is known about factors influencing the occurrence of sub-microscopic parasitaemia or the relation with immune responses.We investigated possible associations between the occurrence of sub-microscopic P. falciparum parasite carriage and antibody responses to the asexual stage antigens, G6PD deficiency and alpha+-thalassaemia in 464 subjects from a low endemic area in northern Tanzania. METHODS: We used samples collected from two cross sectional surveys conducted during dry and wet season in 2005. Submicroscopic parasitaemia was detected by using quantitative nucleic acid sequence based amplification (QT-NASBA). Genotyping for G6PD and alpha+-thalassaemia were performed by high throughput PCR; the prevalence and level of total IgG antibodies against MSP-1, MSP-2 and AMA-1 were determined by ELISA. RESULTS: Compared to parasite free individuals, individuals carrying sub-microscopic densities of P. falciparum parasites had significantly higher median antibody levels to MSP-1 (p = 0.042) and MSP-2 (p = 0.034) but not to AMA-1 (p = 0.14) while no clear relation between sub-microscopic parasite carriage and G6PD deficiency or alpha+-thalassaemia was observed. CONCLUSION: Our data suggest a role for sub-microscopic parasite densities in eliciting or maintaining humoral immune responses without evidence for a modulating effect of G6PD deficiency or alpha+-thalassaemia