13 research outputs found
Dystocia and Foetal Mummification in A West African Dwarf Doe (A Case Report)
Nigerian Veterinary Journal, VOL:32 (4) 357-36
Colostomy for the Relief of a Rectovaginal Fistula and Atresia Recti in a Sow: A Case Report
No Abstrac
Raw, Unadulterated African Honey for Ulcer Healing in Leprosy:Protocol for the Honey Experiment on Leprosy Ulcer (HELP) Randomized Controlled Trial
Background: Leprosy leads to nerve damage and slow-healing ulcers, which are treatable with routine therapy. There has been a recent resurgence of interest in the use of honey for the treatment of different kinds of wounds. Objective: The aim of this study, Honey Experiment on Leprosy Ulcer (HELP), is to evaluate the healing properties of raw, unadulterated African honey in comparison with normal saline dressing for the treatment leprosy ulcers. Methods: This is a multicenter, comparative, prospective, single-blinded, parallel-group, and 1:1 individually randomized controlled trial to be conducted at The Leprosy Referral Hospital, Chanchaga in Minna, Niger State, North Central Nigeria, and St. Benedict Tuberculosis and Leprosy Rehabilitation Hospital in Ogoja, Cross River State, South-South Nigeria. Raw, unadulterated honey will be used in the ulcer dressing of eligible, consenting participants in the intervention group, whereas those in the control group will be treated by dressing with normal saline. The main outcomes will be the proportion of complete healing and the rate of healing up to 84 days after randomization. Follow-up will be conducted 6 months after randomization. We aim to enroll 90‐130 participants into the study. Blinded observers will examine photographs of ulcers to determine the outcomes. Results: The recruitment of trial participants began on March 14, 2022, and has been continuing for approximately 24 months. Conclusions: Our study will provide an unbiased estimate of the effect of honey on the healing of neuropathic ulcers. Trial Registration: ISRCTN registry ISRCTN10093277; https://www.isrctn.com/ISRCTN1009327