11 research outputs found
Human papillomavirus genotype distribution in cervical samples collected in routine clinical practice at the Nantes University Hospital, France
Human Papillomavirus Types Distribution in Organised Cervical Cancer Screening in France
Two sides of a cellular coin: CD4+CD3- cells orchestrate memory antibody responses and lymph node organisation
We propose that CD4(+)CD3(−) cells have two functions: a well-established role in organizing lymphoid tissue during development, and a newly discovered role in supporting T-cell help for B cells both during affinity maturation in germinal centres and for memory antibody responses. As CD4(+)CD3(−) cells express the HIV co-receptors CD4 and CXC-chemokine receptor 4, we think that infection of these cells by HIV, and their subsequent destruction by the host immune system, could help to explain the loss of memory antibody responses and the destruction of lymphoid architecture that occur during disease progression to AIDS