Influence of environmental temperature and electrolyte balance on the performance of quails (Coturnix Coturnix Coturnix)

High environmental temperatures have a negative effect on the production efficiency of poultry reared in hot climates. This study evaluated the efficiency of electrolyte supplementation under high environmental temperature conditions by manipulating water and feed electrolyte balance (EB) on the survival and performance of European quails. In experiment 1, a completely randomized experimental design was applied in a 4 x 2 factorial arrangement. Treatments consisted in four feed EB values (0, 120, 240, 360 mEq/kg), and two environmental temperatures (25 and 34 ºC). Feed electrolyte balance was manipulated by the addition of sodium bicarbonate and ammonium chloride. In experiment 2, birds were randomly distributed according to a 5 x 2 factorial arrangement. Treatments consisted in five BE values in the drinking water (0, 30, 60, 90, 120 mEq/L) and two environmental temperatures (25 and 34 °C). Only sodium bicarbonate was added to the water to obtain the different BE values. The experiments were carried out simultaneously in environmental chambers at constant temperatures with 20- to 37-d-old quails. Most evaluated parameters were influenced by temperature in both experiments. In experiment 1, EB affected water intake and intestinal length. In experiment 2, EB values influenced (p < 0.05) water intake and heart and liver relative weights. Electrolyte balance values of 120 mEq/kg of feed and of 30 mEq/L of drinking water are recommended to increase water intake of grower European quails reared under hot temperature.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES

Adolescent transport and unintentional injuries: a systematic analysis using the Global Burden of Disease Study 2019

BACKGROUND: Globally, transport and unintentional injuries persist as leading preventable causes of mortality and morbidity for adolescents. We sought to report comprehensive trends in injury-related mortality and morbidity for adolescents aged 10-24 years during the past three decades. METHODS: Using the Global Burden of Disease, Injuries, and Risk Factors 2019 Study, we analysed mortality and disability-adjusted life-years (DALYs) attributed to transport and unintentional injuries for adolescents in 204 countries. Burden is reported in absolute numbers and age-standardised rates per 100 000 population by sex, age group (10-14, 15-19, and 20-24 years), and sociodemographic index (SDI) with 95% uncertainty intervals (UIs). We report percentage changes in deaths and DALYs between 1990 and 2019. FINDINGS: In 2019, 369 061 deaths (of which 214 337 [58%] were transport related) and 31·1 million DALYs (of which 16·2 million [52%] were transport related) among adolescents aged 10-24 years were caused by transport and unintentional injuries combined. If compared with other causes, transport and unintentional injuries combined accounted for 25% of deaths and 14% of DALYs in 2019, and showed little improvement from 1990 when such injuries accounted for 26% of adolescent deaths and 17% of adolescent DALYs. Throughout adolescence, transport and unintentional injury fatality rates increased by age group. The unintentional injury burden was higher among males than females for all injury types, except for injuries related to fire, heat, and hot substances, or to adverse effects of medical treatment. From 1990 to 2019, global mortality rates declined by 34·4% (from 17·5 to 11·5 per 100 000) for transport injuries, and by 47·7% (from 15·9 to 8·3 per 100 000) for unintentional injuries. However, in low-SDI nations the absolute number of deaths increased (by 80·5% to 42 774 for transport injuries and by 39·4% to 31 961 for unintentional injuries). In the high-SDI quintile in 2010-19, the rate per 100 000 of transport injury DALYs was reduced by 16·7%, from 838 in 2010 to 699 in 2019. This was a substantially slower pace of reduction compared with the 48·5% reduction between 1990 and 2010, from 1626 per 100 000 in 1990 to 838 per 100 000 in 2010. Between 2010 and 2019, the rate of unintentional injury DALYs per 100 000 also remained largely unchanged in high-SDI countries (555 in 2010 vs 554 in 2019; 0·2% reduction). The number and rate of adolescent deaths and DALYs owing to environmental heat and cold exposure increased for the high-SDI quintile during 2010-19. INTERPRETATION: As other causes of mortality are addressed, inadequate progress in reducing transport and unintentional injury mortality as a proportion of adolescent deaths becomes apparent. The relative shift in the burden of injury from high-SDI countries to low and low-middle-SDI countries necessitates focused action, including global donor, government, and industry investment in injury prevention. The persisting burden of DALYs related to transport and unintentional injuries indicates a need to prioritise innovative measures for the primary prevention of adolescent injury. FUNDING: Bill & Melinda Gates Foundation