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Draft Genome Sequences of Two Vibrio parahaemolyticus Strains Associated with Gastroenteritis after Raw Seafood Ingestion in Colorado.
Vibrio parahaemolyticus is a Gram-negative pathogen associated with gastrointestinal and wound infections after exposure to raw seafood or contaminated waters. We report here the whole-genome sequences of two stool isolates (CDC-AM50933 and CDC-AM43539) from patients in Colorado presenting with gastroenteritis after ingesting raw seafood
Seismicity along the Azores-Gibraltar region controlled by global plates’kinematics
The seismicity along the western part of the Eurasia-Nubian plate boundary has been widely studied and is charac- terized by a very complex pattern. The movement is transtensional in the Azores, dextral along the Gloria transform and convergent between the SW Atlantic margin and the Ibero-Maghrebian zone. In order to understand geograph- ical evolution of the seismicity pattern along this plate frontier, we compare it to the global plate kinematics. More precisely, we consider the difference between the kinematics velocities, supplied by several global kinematics mod- els, across of the Eurasia and Nubian plates. We find a good correlation between this difference of the kinematics velocities and the slip vector provided by the seismicity. Indeed, the directions of these vectors are very similar. A change in the direction of the displacement vector is systematically associated with a similar change of the vector representing the difference of the kinematics velocities. This points out that the seismicity pattern would be con- trolled by the global plates’ kinematics. More quantitatively, the norm of the difference of the kinematics velocities also scales with the slip velocity deduced from the seismicity studies
Marketing data: Has the rise of impact factor led to the fall of objective language in the scientific article?
The language of science should be objective and detached and should place data in the appropriate context. The aim of this commentary was to explore the notion that recent trends in the use of language have led to a loss of objectivity in the presentation of scientific data. The relationship between the value-laden vocabulary and impact factor among fundamental biomedical research and clinical journals has been explored. It appears that fundamental research journals of high impact factors have experienced a rise in value-laden terms in the past 25 years
Search for Low-Scale Technicolor in ATLAS
The low scale technicolor is an appealing scenario of strong ewsb. It has a rich phenomenology which can be tested at the LHC. A very characteristic signal would involve the observation of a technipion in resonance with a Standard Model gauge boson. A fast simulation analysis of the process and for three representative sets of masses for the new particles suggests that the technirho and technipion could be observed with fb, and that the could be observed simultaneously with the and within a year or more of running at the LHC
A prediction of cell differentiation and proliferation within a collagen-glycosaminoglycan scaffold subjected to mechanical strain and perfusive fluid flow.
Mesenchymal stem cell (MSC) differentiation can be influenced by biophysical stimuli imparted by the host scaffold. Yet, causal relationships linking scaffold strain magnitudes and inlet fluid velocities to specific cell responses are thus far underdeveloped. This investigation attempted to simulate cell responses in a collagen-glycosaminoglycan (CG) scaffold within a bioreactor. CG scaffold deformation was simulated using micro-computed tomography (CT) and an in-house finite element solver (FEEBE/linear). Similarly, the internal fluid velocities were simulated using the afore-mentioned microCT dataset with a computational fluid dynamics solver (ANSYS/CFX). From the ensuing cell-level mechanics, albeit octahedral shear strain or fluid velocity, the proliferation and differentiation of the representative cells were predicted from deterministic functions. Cell proliferation patterns concurred with previous experiments. MSC differentiation was dependent on the level of CG scaffold strain and the inlet fluid velocity. Furthermore, MSC differentiation patterns indicated that specific combinations of scaffold strains and inlet fluid flows cause phenotype assemblies dominated by single cell types. Further to typical laboratory procedures, this predictive methodology demonstrated loading-specific differentiation lineages and proliferation patterns. It is hoped these results will enhance in-vitro tissue engineering procedures by providing a platform from which the scaffold loading applications can be tailored to suit the desired tissue
Degrees of Freedom of the Quark Gluon Plasma, tested by Heavy Mesons
Heavy quarks (charm and bottoms) are one of the few probes which are
sensitive to the degrees of freedom of a Quark Gluon Plasma (QGP), which cannot
be revealed by lattice gauge calculations in equilibrium. Due to the rapid
expansion of the QGP energetic heavy quarks do not come to an equilibrium with
the QGP. Their energy loss during the propagation through the QGP medium
depends strongly on the modelling of the interaction of the heavy quarks with
the QGP quarks and gluons, i.e. on the assuption of the degrees of freedom of
the plasma. Here we compare the results of different models, the pQCD based
Monte-Carlo (MC@sHQ), the Dynamical Quasi Particle Model (DQPM) and the
effective mass approach, for the drag force in a thermalized QGP and discuss
the sensitivity of heavy quark energy loss on the properties of the QGP as well
as on non-equilibrium dynamicsComment: proceedings symposion "New Horizons" Makutsi, South Africa, Nov 201
LHC Searches for Non-Chiral Weakly Charged Multiplets
Because the TeV-scale to be probed at the Large Hadron Collider should shed
light on the naturalness, hierarchy, and dark matter problems, most searches to
date have focused on new physics signatures motivated by possible solutions to
these puzzles. In this paper, we consider some candidates for new states that
although not well-motivated from this standpoint are obvious possibilities that
current search strategies would miss. In particular we consider vector
representations of fermions in multiplets of with a lightest neutral
state. Standard search strategies would fail to find such particles because of
the expected small one-loop-level splitting between charged and neutral states.Comment: 16 pages, 9 figure
Identifying and Managing Frailty: A Survey of UK Healthcare Professionals
Frailty is a common condition that leads to multiple adverse outcomes. Frailty should be identified and managed in a holistic, evidence-based and patient-centered way. We aimed to understand how UK healthcare professionals (HCPs) identify and manage frailty in comparison with UK Fit for Frailty guidelines, their frailty training, their confidence in providing support and organizational pathways for this. An online mixed-methods survey was distributed to UK HCPs supporting older people through professional bodies, special interest groups, key contacts, and social media. From 137 responses, HCPs valued frailty assessment but used a mixture of tools that varied by profession. HCPs felt confident managing frailty and referred older people to a wide range of supportive services, but acknowledged a lack of formalized training opportunities, systems, and pathways for frailty management. Clearer pathways, more training, and stronger interprofessional communication, appropriate to each setting, may further support HCPs in frailty management
Outcome following surgery for colorectal cancer: analysis by hospital after adjustment for case-mix and deprivation
Outcome, adjusted for case-mix and deprivation, in 3200 patients undergoing resection for colorectal cancer in 11 hospitals in Central Scotland between 1991 and 1994 was studied. There were significant differences among individual hospitals in the proportion of elderly (P<0.001) and deprived (P<0.0001) patients, the mode (P=0.007) and stage (P<0.0001) at presentation, and the proportion of patients who underwent apparently curative resection (P<0.001). There were no significant differences in postoperative mortality. Cancer-specific survival at 5 years following apparently curative resection varied from 59 to 76%; cancer-specific survival at 2 years following palliative resection varied from 22 to 44%. The corresponding hazard ratios, adjusted for the above prognostic factors, for patients undergoing apparently curative resection varied among hospitals from 0.58 to 1.32; and the ratios for palliative resection varied from 0.73 to 1.26. This study demonstrates that, after adjustment for variations in case-mix and deprivation, significant differences in outcome among hospitals following resection for colorectal cancer persist
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