65 research outputs found

    High-resolution Velocity Fields of Low-mass Disk Galaxies. I. CO Observations

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    This paper is the first in a series whose aim is to examine the relative distributions of dark and baryonic matter as a function of star formation history in a representative sample of low-mass disk galaxies. In this paper, we present high-resolution 12 CO(j=1β†’0) interferometry for a sample of 26 nearby dwarf galaxies that were obtained from the Combined Array for Research in Millimeter-wave Astronomy (CARMA). Among these 26 galaxies, 14 have good CO detections, including 6 galaxies previously detected in single-dish CO measurements and 8 newly detected ones. We find a linear correlation between the CO flux and the mid- and far-IR flux from the WISE and IRAS catalogs. Compared to the far-IR flux, the mid-IR flux may be a better indication of whether a galaxy contains sufficient CO for detection at the level of instrument sensitivity of CARMA. This correlation might prove to be useful in future studies to help choosing other CO targets for observation. The median molecular mass (including helium) of our galaxies is 2.8Γ—10 8 MβŠ™, which is consistent with past observations for dwarf galaxies. The molecular content is weakly correlated with the dynamical mass, r-band luminosity and size of the galaxies. The median ratios of molecular mass versus dynamical mass and molecular mass versus r-band luminosity are M mol M dyn β‰ˆ 0.035 and M mol L r β‰ˆ 0.078MβŠ™ L r , βŠ™, respectively, which are also consistent with past observations for dwarf galaxies

    High-resolution Velocity Fields of Low-mass Disk Galaxies. I. CO Observations

    Get PDF
    This paper is the first in a series whose aim is to examine the relative distributions of dark and baryonic matter as a function of star formation history in a representative sample of low-mass disk galaxies. In this paper, we present high-resolution 12 CO(j=1β†’0) interferometry for a sample of 26 nearby dwarf galaxies that were obtained from the Combined Array for Research in Millimeter-wave Astronomy (CARMA). Among these 26 galaxies, 14 have good CO detections, including 6 galaxies previously detected in single-dish CO measurements and 8 newly detected ones. We find a linear correlation between the CO flux and the mid- and far-IR flux from the WISE and IRAS catalogs. Compared to the far-IR flux, the mid-IR flux may be a better indication of whether a galaxy contains sufficient CO for detection at the level of instrument sensitivity of CARMA. This correlation might prove to be useful in future studies to help choosing other CO targets for observation. The median molecular mass (including helium) of our galaxies is 2.8Γ—10 8 MβŠ™, which is consistent with past observations for dwarf galaxies. The molecular content is weakly correlated with the dynamical mass, r-band luminosity and size of the galaxies. The median ratios of molecular mass versus dynamical mass and molecular mass versus r-band luminosity are M mol M dyn β‰ˆ 0.035 and M mol L r β‰ˆ 0.078MβŠ™ L r , βŠ™, respectively, which are also consistent with past observations for dwarf galaxies

    The Dark Matter Distributions in Low-Mass Disk Galaxies. I. HΞ± Observations Using the Palomar Cosmic Web Imager

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    Dark-matter-only simulations predict that dark matter halos have cusp-like inner density profiles, while observations of low-mass galaxies have found a range of inner slopes that are typically much shallower. It is still not well established whether this discrepancy can be explained by baryonic feedback or if it may require modified dark matter models. To better understand the diversity of dark matter profiles in dwarf galaxies, we undertook a survey of 26 low-mass galaxies (\mathrm{log}{M}_{* }/{M}_{\odot }=8.4\mbox{--}9.8, v max = 50–140 km sβˆ’1) within 30 Mpc using the Palomar Cosmic Web Imager, which is among the largest integral field spectroscopic surveys of its type. In this paper, we derive HΞ± velocity fields for the full sample with a typical spatial resolution of ~160 pc. We extract rotation curves and verify their robustness to several choices in the analysis. We present a method for improving the velocity precision obtained from image slicing spectrographs using narrowband HΞ± images. For 11 galaxies, we compare the HΞ± velocity fields to CO kinematics measured using CARMA, finding the maps to be in good agreement. The standard deviation of the difference is typically ~7 km sβˆ’1, comparable to the level of turbulence in the interstellar medium, showing that the two tracers have substantially the same bulk kinematics. In a companion paper, we will use the rotation curves produced here to construct mass models of the galaxies and determine their dark matter density profiles

    Mapping Peptidergic Cells in Drosophila: Where DIMM Fits In

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    The bHLH transcription factor DIMMED has been associated with the differentiation of peptidergic cells in Drosophila. However, whether all Drosophila peptidergic cells express DIMM, and the extent to which all DIMM cells are peptidergic, have not been determined. To address these issues, we have mapped DIMM expression in the central nervous system (CNS) and periphery in the late larval stage Drosophila. At 100 hr after egg-laying, DIMM immunosignals are largely congruent with a dimm-promoter reporter (c929-GAL4) and they present a stereotyped pattern of 306 CNS cells and 52 peripheral cells. We assigned positional values for all DIMM CNS cells with respect to reference gene expression patterns, or to patterns of secondary neuroblast lineages. We could assign provisional peptide identities to 68% of DIMM-expressing CNS cells (207/306) and to 73% of DIMM-expressing peripheral cells (38/52) using a panel of 24 markers for Drosophila neuropeptide genes. Furthermore, we found that DIMM co-expression was a prevalent feature within single neuropeptide marker expression patterns. Of the 24 CNS neuropeptide gene patterns we studied, six patterns are >90% DIMM-positive, while 16 of 22 patterns are >40% DIMM-positive. Thus most or all DIMM cells in Drosophila appear to be peptidergic, and many but not all peptidergic cells express DIMM. The co-incidence of DIMM-expression among peptidergic cells is best explained by a hypothesis that DIMM promotes a specific neurosecretory phenotype we term LEAP. LEAP denotes Large cells that display Episodic release of Amidated Peptides

    Modulation of the Ξ²-Catenin Signaling Pathway by the Dishevelled-Associated Protein Hipk1

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    BACKGROUND:Wnts are evolutionarily conserved ligands that signal through beta-catenin-dependent and beta-catenin-independent pathways to regulate cell fate, proliferation, polarity, and movements during vertebrate development. Dishevelled (Dsh/Dvl) is a multi-domain scaffold protein required for virtually all known Wnt signaling activities, raising interest in the identification and functions of Dsh-associated proteins. METHODOLOGY:We conducted a yeast-2-hybrid screen using an N-terminal fragment of Dsh, resulting in isolation of the Xenopus laevis ortholog of Hipk1. Interaction between the Dsh and Hipk1 proteins was confirmed by co-immunoprecipitation assays and mass spectrometry, and further experiments suggest that Hipk1 also complexes with the transcription factor Tcf3. Supporting a nuclear function during X. laevis development, Myc-tagged Hipk1 localizes primarily to the nucleus in animal cap explants, and the endogenous transcript is strongly expressed during gastrula and neurula stages. Experimental manipulations of Hipk1 levels indicate that Hipk1 can repress Wnt/beta-catenin target gene activation, as demonstrated by beta-catenin reporter assays in human embryonic kidney cells and by indicators of dorsal specification in X. laevis embryos at the late blastula stage. In addition, a subset of Wnt-responsive genes subsequently requires Hipk1 for activation in the involuting mesoderm during gastrulation. Moreover, either over-expression or knock-down of Hipk1 leads to perturbed convergent extension cell movements involved in both gastrulation and neural tube closure. CONCLUSIONS:These results suggest that Hipk1 contributes in a complex fashion to Dsh-dependent signaling activities during early vertebrate development. This includes regulating the transcription of Wnt/beta-catenin target genes in the nucleus, possibly in both repressive and activating ways under changing developmental contexts. This regulation is required to modulate gene expression and cell movements that are essential for gastrulation
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