Torsion Galois representations over CM fields and Hecke algebras in the derived category

We construct algebras of endomorphisms in the derived category of the cohomology of arithmetic manifolds, which are generated by Hecke operators. We construct Galois representations with coefficients in these Hecke algebras and apply this technique to sharpen recent results of P. Scholze

Influence of viscoelasticity and interfacial slip on acoustic wave sensors

Acoustic wave devices with shear horizontal displacements, such as quartz crystal microbalances (QCM) and shear horizontally polarised surface acoustic wave (SH-SAW) devices provide sensitive probes of changes at solid-solid and solid- liquid interfaces. Increasingly the surfaces of acoustic wave devices are being chemically or physically modified to alter surface adhesion or coated with one or more layers to amplify their response to any change of mass or material properties. In this work, we describe a model that provides a unified view of the modification in the shear motion in acoustic wave systems by multiple finite thickness loadings of viscoelastic fluids. This model encompasses QCM and other classes of acoustic wave devices based on a shear motion of the substrate surface and is also valid whether the coating film has a liquid or solid character. As a specific example, the transition of a coating from liquid to solid is modelled using a single relaxation time Maxwell model. The correspondence between parameters from this physical model and parameters from alternative acoustic impedance models is given explicitly. The characteristic changes in QCM frequency and attenuation as a function of thickness are illustrated for a single layer device as the coating is varied from liquid-like to that of an amorphous solid. Results for a double layer structure are given explicitly and the extension of the physical model to multiple layers is described

TORSION GALOIS REPRESENTATIONS over CM FIELDS and HECKE ALGEBRAS in the DERIVED CATEGORY

We construct algebras of endomorphisms in the derived category of the cohomology of arithmetic manifolds, which are generated by Hecke operators. We construct Galois representations with coefficients in these Hecke algebras and apply this technique to sharpen recent results of P. Scholze.This research was partially conducted during the period that Jack Thorne served as a Clay Research Fellow. James Newton is supported by the ERC Starting grant 306326.This is the final version of the article. It first appeared from Cambridge University Press via http://dx.doi.org/10.1017/fms.2016.1

Children with severe malnutrition: can those at highest risk of death be identified with the WHO protocol?

Background With strict adherence to international recommended treatment guidelines, the case fatality for severe malnutrition ought to be less than 5%. In African hospitals, fatality rates of 20% are common and are often attributed to poor training and faulty case management. Improving outcome will depend upon the identification of those at greatest risk and targeting limited health resources. We retrospectively examined the major risk factors associated with early (<48 h) and late in-hospital death in children with severe malnutrition with the aim of identifying admission features that could distinguish a high-risk group in relation to the World Health Organization (WHO) guidelines. Methods and Findings Of 920 children in the study, 176 (19%) died, with 59 (33%) deaths occurring within 48 h of admission. Bacteraemia complicated 27% of all deaths: 52% died before 48 h despite 85% in vitro antibiotic susceptibility of cultured organisms. The sensitivity, specificity, and likelihood ratio of the WHO-recommended “danger signs” (lethargy, hypothermia, or hypoglycaemia) to predict early mortality was 52%, 84%, and 3.4% (95% confidence interval [CI] = 2.2 to 5.1), respectively. In addition, four bedside features were associated with early case fatality: bradycardia, capillary refill time greater than 2 s, weak pulse volume, and impaired consciousness level; the presence of two or more features was associated with an odds ratio of 9.6 (95% CI = 4.8 to 19) for early fatality (p < 0.0001). Conversely, the group of children without any of these seven features, or signs of dehydration, severe acidosis, or electrolyte derangements, had a low fatality (7%). Conclusions Formal assessment of these features as emergency signs to improve triage and to rationalize manpower resources toward the high-risk groups is required. In addition, basic clinical research is necessary to identify and test appropriate supportive treatments

Automorphy lifting for residually reducible-adic Galois representations, II

We revisit the paper [Automorphy lifting for residually reducible$l$-adic Galois representations, J. Amer. Math. Soc. 28 (2015), 785–870] by the third author. We prove new automorphy lifting theorems for residually reducible Galois representations of unitary type in which the residual representation is permitted to have an arbitrary number of irreducible constituents.This work was partially conducted during the period that J.T. served as a Clay Research Fellow. J.T.’s work received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement No 714405). J.T. would like to thank Lue Pan for pointing out an error in [Tho15], which is addressed here in §3.1 below. P.A. was supported by Simons Foundation Collaboration Grant 527275 and NSF grant DMS- 1902155

Helicobacter pylori and cancer among adults in Uganda

Data from Africa on infection with Helicobacter pylori (H. pylori) are sparse. Therefore, as part of an epidemiological study of cancer in Uganda, we investigated the prevalence and determinants of antibodies against H. pylori among 854 people with different cancer types and benign tumours. Patients were recruited from hospitals in Kampala, Uganda, interviewed about various demographic and lifestyle factors and tested for antibodies against H. pylori. In all patients combined, excluding those with stomach cancer (which has been associated with H. pylori infection), the prevalence of antibodies was 87% (723/833) overall, but declined with increasing age (p = 0.02) and was lower among people who were HIV seropositive compared to seronegative (p <0.001). Otherwise, there were few consistent epidemiological associations. Among those with stomach cancer, 18/21 (86%) had anti-H. pylori antibodies (odds ratio 0.8, 95% confidence intervals 0.2–2.9, p = 0.7; estimated using all other patients as controls, with adjustment for age, sex and HIV serostatus). No other cancer site or type was significantly associated with anti-H. pylori antibodies. The prevalence of H. pylori reported here is broadly in accord with results from other developing countries, although the determinants of infection and its' role in the aetiology of gastric cancer in Uganda remain unclear

Parents' expectations and perceptions concerning the provision of communication aids by the Communication Aids Project (CAP)

This paper reports findings from part of an evaluation study of the Communication Aids Project (CAP), a government-funded project in England which provided communication aids to school-aged children. The paper focuses on parents'views of the CAP process and the impact of the aid. Fourteen parents were interviewed twice over the telephone: once before or just as their children received communication aids and again six to eight weeks later. Parents expressed satisfaction with the impact of the aid on their children's lives and showed they had realistic expectations concerning potential short- and long-term benefits. They raised two main concerns regarding the provision of aids, namely the timescale involved and access to accurate information and advice

Communication aids in the classroom: the views of education staff and speech and language therapists involved with the Communication Aids Project

The findings presented in this paper are part of an independent evaluation study of the Communication Aids Project (CAP). The study was carried out between July 2003 and April 2004 and looked at the impact of CAP on children receiving communication aids and evaluated the CAP strategy of assessment and delivery. In this paper the views of education staff and speech and language therapists who were working with communication aid users in school are presented. The professionals who were interviewed provided positive feedback on the existence of CAP, on the assessment for the communication aid, particularly where the use of the aid in the classroom was considered, and on the children's increased participation in classroom and learning activities since receiving the aid. They also highlighted the issue of managing parents' expectations regarding the use of aids and the value of and need for continued training for professionals working with communication aids in the classroom. The authors of this article, Jannet Wright, senior lecturer, Chris Donlan, senior lecturer, Caroline Newton, lecturer, and Michael Clarke, lecturer, from University College London; Claire Lister, from the Institute of Child Health, London; and Jasmina Cherguit, assistant psychologist, draw upon their findings to develop recommendations for future policy, practice and professional development

Communication aids in the classroom: the views of education staff and speech and language therapists involved with the Communication Aids Project

The findings presented in this paper are part of an independent evaluation study of the Communication Aids Project (CAP). The study was carried out between July 2003 and April 2004 and looked at the impact of CAP on children receiving communication aids and evaluated the CAP strategy of assessment and delivery. In this paper the views of education staff and speech and language therapists who were working with communication aid users in school are presented. The professionals who were interviewed provided positive feedback on the existence of CAP, on the assessment for the communication aid, particularly where the use of the aid in the classroom was considered, and on the children's increased participation in classroom and learning activities since receiving the aid. They also highlighted the issue of managing parents' expectations regarding the use of aids and the value of and need for continued training for professionals working with communication aids in the classroom. The authors of this article, Jannet Wright, senior lecturer, Chris Donlan, senior lecturer, Caroline Newton, lecturer, and Michael Clarke, lecturer, from University College London; Claire Lister, from the Institute of Child Health, London; and Jasmina Cherguit, assistant psychologist, draw upon their findings to develop recommendations for future policy, practice and professional development