65 research outputs found
Newtonian Collapse of Scalar Field Dark Matter
In this letter, we develop a Newtonian approach to the collapse of galaxy
fluctuations of scalar field dark matter under initial conditions inferred from
simple assumptions. The full relativistic system, the so called
Einstein-Klein-Gordon, is reduced to the Schr\"odinger-Newton one in the weak
field limit. The scaling symmetries of the SN equations are exploited to track
the non-linear collapse of single scalar matter fluctuations. The results can
be applied to both real and complex scalar fields.Comment: 4 pages RevTex4 file, 4 eps figure
Evolution of the Schr\"odinger--Newton system for a self--gravitating scalar field
Using numerical techniques, we study the collapse of a scalar field
configuration in the Newtonian limit of the spherically symmetric
Einstein--Klein--Gordon (EKG) system, which results in the so called
Schr\"odinger--Newton (SN) set of equations. We present the numerical code
developed to evolve the SN system and topics related, like equilibrium
configurations and boundary conditions. Also, we analyze the evolution of
different initial configurations and the physical quantities associated to
them. In particular, we readdress the issue of the gravitational cooling
mechanism for Newtonian systems and find that all systems settle down onto a
0--node equilibrium configuration.Comment: RevTex file, 19 pages, 26 eps figures. Minor changes, matches version
to appear in PR
Maintenance Therapies for Hodgkin and Non-Hodgkin Lymphomas after Autologous Transplantation: A Consensus Project of ASBMT, CIBMTR, and the Lymphoma Working Party of EBMT
Importance: Maintenance therapies are often considered as a therapeutic strategy in patients with lymphoma following autologous hematopoietic cell transplantation (auto-HCT) to mitigate the risk of disease relapse. With an evolving therapeutic landscape, where novel drugs are moving earlier in therapy lines, evidence relevant to contemporary practice is increasingly limited. The American Society for Blood and Marrow Transplantation (ASBMT), Center for International Blood and Marrow Transplant Research (CIBMTR), and European Society for Blood and Marrow Transplantation (EBMT) jointly convened an expert panel with diverse expertise and geographical representation to formulate consensus recommendations regarding the use of maintenance and/or consolidation therapies after auto-HCT in patients with lymphoma. Observations: The RAND-modified Delphi method was used to generate consensus statements where at least 75% vote in favor of a recommendation was considered as consensus. The process included 3 online surveys moderated by an independent methodological expert to ensure anonymity and an in-person meeting. The panel recommended restricting the histologic categories covered in this project to Hodgkin lymphoma (HL), mantle cell lymphoma (MCL), diffuse large B-cell lymphoma (DLBCL), and follicular lymphoma. On completion of the voting process, the panel generated 22 consensus statements regarding post auto-HCT maintenance and/or consolidation therapies. The grade A recommendations included endorsement of: (1) brentuximab vedotin (BV) maintenance and/or consolidation in BV-na\uefve high-risk HL, (2) rituximab maintenance in MCL undergoing auto-HCT after first-line therapy, (3) rituximab maintenance in rituximab-na\uefve FL, and (4) No post auto-HCT maintenance was recommended in DLBCL. The panel also developed consensus statements for important real-world clinical scenarios, where randomized data are lacking to guide clinical practice. Conclusions and Relevance: In the absence of contemporary evidence-based data, the panel found RAND-modified Delphi methodology effective in providing a rigorous framework for developing consensus recommendations for post auto-HCT maintenance and/or consolidation therapies in lymphoma.
Supermassive black holes in scalar field galaxy halos
Ultra-light scalar fields provide an interesting alternative to WIMPS as halo
dark matter. In this paper we consider the effect of embedding a supermassive
black hole within such a halo, and estimate the absorption probability and the
accretion rate of dark matter onto the black hole. We show that the accretion
rate would be small over the lifetime of a typical halo, and hence that
supermassive central black holes can coexist with scalar field halos.Comment: 5 pages RevTex4, no figures. Updated file to match published versio
The Effect of Different Levels of Iodide Feeding on Serum Inorganic and Protein-Bound Iodine, with a Note on the Frequency of Administration Required to Maintain a High Level of Serum Inorganic Iodine
Safety and efficacy of ofatumumab in patients with fludarabine and alemtuzumab refractory chronic lymphocytic leukaemia
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