1,123 research outputs found
On the influence of noise on chaos in nearly Hamiltonian systems
The simultaneous influence of small damping and white noise on Hamiltonian
systems with chaotic motion is studied on the model of periodically kicked
rotor. In the region of parameters where damping alone turns the motion into
regular, the level of noise that can restore the chaos is studied. This
restoration is created by two mechanisms: by fluctuation induced transfer of
the phase trajectory to domains of local instability, that can be described by
the averaging of the local instability index, and by destabilization of motion
within the islands of stability by fluctuation induced parametric modulation of
the stability matrix, that can be described by the methods developed in the
theory of Anderson localization in one-dimensional systems.Comment: 10 pages REVTEX, 9 figures EP
Systemic Administration Of Pleiotrophin Induces Hematopoietic Stem Cell (HSC) Regeneration in vivo
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An ion trap built with photonic crystal fibre technology
We demonstrate a surface-electrode ion trap fabricated using techniques transferred from the manufacture of photonic-crystal fibres. This provides a relatively straightforward route for realizing traps with an electrode structure on the 100 micron scale with high optical access. We demonstrate the basic functionality of the trap by cooling a single ion to the quantum ground state, allowing us to measure a heating rate from the ground state of 787 ± 24 quanta/s. Variation of the fabrication procedure used here may provide access to traps in this geometry with trap scales between 100 μm and 10 μ
On the deflection of asteroids with mirrors
This paper presents an analysis of an asteroid deflection method based on multiple solar concentrators. A model of the deflection through the sublimation of the surface material of an asteroid is presented, with simulation results showing the achievable orbital deflection with, and without, accounting for the effects of mirror contamination due to the ejected debris plume. A second model with simulation results is presented analyzing an enhancement of the Yarkovsky effect, which provides a significant deflection even when the surface temperature is not high enough to sublimate. Finally the dynamical model of solar concentrators in the proximity of an irregular celestial body are discussed, together with a Lyapunov-based controller to maintain the spacecraft concentrators at a required distance from the asteroid
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Persistent reduced ecosystem respiration after insect disturbance in high elevation forests
Amid a worldwide increase in tree mortality, mountain pine beetles (Dendroctonus ponderosae Hopkins) have led to the death of billions of trees from Mexico to Alaska since 2000. This is predicted to have important carbon, water and energy balance feedbacks on the Earth system. Counter to current projections, we show that on a decadal scale, tree mortality causes no increase in ecosystem respiration from scales of several square metres up to an 84 km2 valley. Rather, we found comparable declines in both gross primary productivity and respiration suggesting little change in net flux, with a transitory recovery of respiration 6–7 years after mortality associated with increased incorporation of leaf litter C into soil organic matter, followed by further decline in years 8–10. The mechanism of the impact of tree mortality caused by these biotic disturbances is consistent with reduced input rather than increased output of carbon
Big Bang Nucleosynthesis with Gaussian Inhomogeneous Neutrino Degeneracy
We consider the effect of inhomogeneous neutrino degeneracy on Big Bang
nucleosynthesis for the case where the distribution of neutrino chemical
potentials is given by a Gaussian. The chemical potential fluctuations are
taken to be isocurvature, so that only inhomogeneities in the electron chemical
potential are relevant. Then the final element abundances are a function only
of the baryon-photon ratio , the effective number of additional neutrinos
, the mean electron neutrino degeneracy parameter , and
the rms fluctuation of the degeneracy parameter, . We find that for
fixed , , and , the abundances of helium-4,
deuterium, and lithium-7 are, in general, increasing functions of .
Hence, the effect of adding a Gaussian distribution for the electron neutrino
degeneracy parameter is to decrease the allowed range for . We show that
this result can be generalized to a wide variety of distributions for .Comment: 9 pages, 3 figures, added discussion of neutrino oscillations,
altered presentation of figure
Decreased fatty acid beta-oxidation in riboflavin-responsive, multiple acylcoenzyme A dehydrogenase-deficient patients is associated with an increase in uncoupling protein-3
Decreased fatty acid beta-oxidation in riboflavin-responsive, multiple acylcoenzyme A dehydrogenase-deficient patients is associated with an increase in uncoupling protein-3.Russell AP, Schrauwen P, Somm E, Gastaldi G, Hesselink MK, Schaart G, Kornips E, Lo SK, Bufano D, Giacobino JP, Muzzin P, Ceccon M, Angelini C, Vergani L.Department of Medical Biochemistry, University of Geneva Medical Center, 1206 Geneva, Switzerland. [email protected], multiple acylcoenzyme A dehydrogenase deficiency (RR-MAD), a lipid storage myopathy, is characterized by, among others, a decrease in fatty acid (FA) beta-oxidation capacity. Muscle uncoupling protein 3 (UCP3) is up-regulated under conditions that either increase the levels of circulating free FA and/or decrease FA beta-oxidation. Using a relatively large cohort of seven RR-MAD patients, we aimed to better characterize the metabolic disturbances of this disease and to explore the possibility that it might increase UCP3 expression. A battery of biochemical and molecular tests were performed, which demonstrated decreases in FA beta-oxidation and in the activities of respiratory chain complexes I and II. These metabolic alterations were associated with increases of 3.1- and 1.7-fold in UCP3 mRNA and protein expression, respectively. All parameters were restored to control values after riboflavin treatment. We postulate that the up-regulation of UCP3 in RR-MAD is due to the accumulation of muscle FA/acylCoA. RR-MAD is an optimal model to support the hypothesis that UCP3 is involved in the outward translocation of an excess of FA from the mitochondria and to show that, in humans, the effects of FA on UCP3 expression are direct and independent of fatty acid beta-oxidation.<br/
Effect of acute exercise on uncoupling protein 3 is a fat metabolism-mediated effect
Department of Human Biology, Maastricht University, 6200 MD Maastricht, The Netherlands. [email protected] Human and rodent uncoupling protein (UCP)3 mRNA is upregulated after acute exercise. Moreover, exercise increases plasma levels of free fatty acid (FFA), which are also known to upregulate UCP3. We investigated whether the upregulation of UCP3 after exercise is an effect of exercise per se or an effect of FFA levels or substrate oxidation. Seven healthy untrained men [age: 22.7 +/- 0.6 yr; body mass index: 23.8 +/- 1.0 kg/m(2); maximal O2 uptake (VO2 max): 3,852 +/- 211 ml/min] exercised at 50% VO2 max for 2 h and then rested for 4 h. Muscle biopsies and blood samples were taken before and immediately after 2 h of exercise and 1 and 4 h in the postexercise period. To modulate plasma FFA levels and fat/glucose oxidation, the experiment was performed two times, one time with glucose ingestion and one time while fasting. UCP3 mRNA and UCP3 protein were determined by RT-competitive PCR and Western blot. In the fasted state, plasma FFA levels significantly increased (P < 0.0001) during exercise (293 +/- 25 vs. 1,050 +/- 127 micromol/l), whereas they were unchanged after glucose ingestion (335 +/- 54 vs. 392 +/- 74 micromol/l). Also, fat oxidation was higher after fasting (P < 0.05), whereas glucose oxidation was higher after glucose ingestion (P < 0.05). In the fasted state, UCP3L mRNA expression was increased significantly (P < 0.05) 4 h after exercise (4.6 +/- 1.2 vs. 9.6 +/- 3.3 amol/microg RNA). This increase in UCP3L mRNA expression was prevented by glucose ingestion. Acute exercise had no effect on UCP3 protein levels. In conclusion, we found that acute exercise had no direct effect on UCP3 mRNA expression. Abolishing the commonly observed increase in plasma FFA levels and/or fatty acid oxidation during and after exercise prevents the upregulation of UCP3 after acute exercise. Therefore, the previously observed increase in UCP3 expression appears to be an effect of prolonged elevation of plasma FFA levels and/or increased fatty acid oxidation
Mapping Vesta: First Results from Dawn’s Survey Orbit
The geologic objectives of the Dawn Mission [1] are
to derive Vesta’s shape, map the surface geology,
understand the geological context and contribute to
the determination of the asteroids’ origin and
evolution.Geomorphology and distribution of surface features
will provide evidence for impact cratering, tectonic activity, volcanism, and regolith processes. Spectral
measurements of the surface will provide evidence of
the compositional characteristics of geological units.
Age information, as derived from crater sizefrequency
distributions, provides the stratigraphic
context for the structural and compositional mapping
results, thus revealing the geologic history of Vesta.
We present here the first results of the Dawn mission
from data collected during the approach to Vesta, and
its first discrete orbit phase – the Survey Orbit, which
lasts 21 days after the spacecraft had established a
circular polar orbit at a radius of ~3000 km with a
beta angle of 10°-15°
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