Observation of diffractive orbits in the spectrum of excited NO in a magnetic field

We investigate the experimental spectra of excited NO molecules in the diamagnetic regime and develop a quantitative semiclassical framework to account for the results. We show the dynamics can be interpreted in terms of classical orbits provided that in addition to the geometric orbits, diffractive effects are appropriately taken into account. We also show how individual orbits can be extracted from the experimental signal and use this procedure to reveal the first experimental manifestation of inelastic diffractive orbits.Comment: 4 fig

An approximate renormalization-group transformation for Hamiltonian systems with three degrees of freedom

We construct an approximate renormalization transformation that combines Kolmogorov-Arnold-Moser (KAM)and renormalization-group techniques, to analyze instabilities in Hamiltonian systems with three degrees of freedom. This scheme is implemented both for isoenergetically nondegenerate and for degenerate Hamiltonians. For the spiral mean frequency vector, we find numerically that the iterations of the transformation on nondegenerate Hamiltonians tend to degenerate ones on the critical surface. As a consequence, isoenergetically degenerate and nondegenerate Hamiltonians belong to the same universality class, and thus the corresponding critical invariant tori have the same type of scaling properties. We numerically investigate the structure of the attracting set on the critical surface and find that it is a strange nonchaotic attractor. We compute exponents that characterize its universality class.Comment: 10 pages typeset using REVTeX, 7 PS figure

Cas9 gene therapy for Angelman syndrome traps Ube3a-ATS long non-coding RNA

Angelman syndrome (AS) is a severe neurodevelopmental disorder caused by a mutation or deletion of the maternally inherited UBE3A allele. In neurons, the paternally inherited UBE3A allele is silenced in cis by a long non-coding RNA called UBE3A-ATS. Here, as part of a systematic screen, we found that Cas9 can be used to activate ('unsilence') paternal Ube3a in cultured mouse and human neurons when targeted to Snord115 genes, which are small nucleolar RNAs that are clustered in the 3′ region of Ube3a-ATS. A short Cas9 variant and guide RNA that target about 75 Snord115 genes were packaged into an adeno-associated virus and administered to a mouse model of AS during the embryonic and early postnatal stages, when the therapeutic benefit of restoring Ube3a is predicted to be greatest1,2. This early treatment unsilenced paternal Ube3a throughout the brain for at least 17 months and rescued anatomical and behavioural phenotypes in AS mice. Genomic integration of the adeno-associated virus vector into Cas9 target sites caused premature termination of Ube3a-ATS at the vector-derived polyA cassette, or when integrated in the reverse orientation, by transcriptional collision with the vector-derived Cas9 transcript. Our study shows that targeted genomic integration of a gene therapy vector can restore the function of paternally inherited UBE3A throughout life, providing a path towards a disease-modifying treatment for a syndromic neurodevelopmental disorder

Magnetic ordering in Sr2RuO4 induced by nonmagnetic impurities

We report unusual effects of nonmagnetic impurities on the spin-triplet superconductor Sr2RuO4. The substitution of nonmagnetic Ti4+ for Ru4+ induces localized-moment magnetism characterized by unexpected Ising anisotropy with the easy axis along the interlayer c direction. Furthermore, for x(Ti) > 0.03 magnetic ordering occurs in the metallic state with the remnant magnetization along the c-axis. We argue that the localized moments are induced in the Ru4+ and/or oxygen ions surrounding Ti4+ and that the ordering is due to their interaction mediated by itinerant Ru-4d electrons with strong spin fluctuations.Comment: 5 pages, 4figure

Vulnerability of existing and planned coal-fired power plants in Developing Asia to changes in climate and water resources

Coal power generation dominates electricity supply in Developing Asia, and more than 400 gigawatts (GW) of new coal-fired capacity is planned for operation by 2030. Past studies on thermal electricity-water nexus have not accounted for this new capacity, and use coarse spatial and temporal resolutions in the assessment of long-term power system reliability. Here, high-resolution hydro-climatic simulations and asset-level power plant water use models are integrated to quantify water constraints on coal-fired power plants in Developing Asia, for different scenarios of future climate change, cooling system choice, and capacity expansion. Future climate change and capacity expansion decrease the annual usable capacity factor (UF) of coal power generation in Mongolia, Southeast Asia, and parts of India and China. The negative impacts are lessened by widening the geographic areas of aggregation. Under near-term mitigation scenarios with high penetrations of CO2 capture technology, the regional average water withdrawal intensity of coal power generation is 50–80% higher than current conditions. With careful siting, the increased water withdrawal intensity does not necessarily constrain future electricity production on annual or monthly time scales, but decreases system reliability by increasing the probability of low UF at daily time scale. Our findings highlight the unaccounted-for-risk in Developing Asia's long-term power plan featuring coal power generation. Regional capacity expansion should consider the reliability of future thermal power assets under long-term hydroclimate change using high-resolution models and multiple scenarios

Enhanced stability of layered phases in parallel hard-spherocylinders due to the addition of hard spheres

There is increasing evidence that entropy can induce microphase separation in binary fluid mixtures interacting through hard particle potentials. One such phase consists of alternating two dimensional liquid-like layers of rods and spheres. We study the transition from a uniform miscible state to this ordered state using computer simulations and compare results to experiments and theory. We conclude that (1) there is stable entropy driven microphase separation in mixtures of parallel rods and spheres, (2) adding spheres smaller then the rod length decreases the total volume fraction needed for the formation of a layered phase, therefore small spheres effectively stabilize the layered phase; the opposite is true for large spheres and (3) the degree of this stabilization increases with increasing rod length.Comment: 11 pages, 9 figures. Submitted to Phys. Rev. E. See related website http://www.elsie.brandeis.ed

Alpha-decay branching ratios of near-threshold states in 19Ne and the astrophysical rate of 15O(alpha,gamma)19Ne

The 15O(alpha,gamma)19Ne reaction is one of two routes for breakout from the hot CNO cycles into the rp process in accreting neutron stars. Its astrophysical rate depends critically on the decay properties of excited states in 19Ne lying just above the 15O + alpha threshold. We have measured the alpha-decay branching ratios for these states using the p(21Ne,t)19Ne reaction at 43 MeV/u. Combining our measurements with previous determinations of the radiative widths of these states, we conclude that no significant breakout from the hot CNO cycle into the rp process in novae is possible via 15O(alpha,gamma)19Ne, assuming current models accurately represent their temperature and density conditions

Structure and Dynamics of Liquid Iron under Earth's Core Conditions

First-principles molecular dynamics simulations based on density-functional theory and the projector augmented wave (PAW) technique have been used to study the structural and dynamical properties of liquid iron under Earth's core conditions. As evidence for the accuracy of the techniques, we present PAW results for a range of solid-state properties of low- and high-pressure iron, and compare them with experimental values and the results of other first-principles calculations. In the liquid-state simulations, we address particular effort to the study of finite-size effects, Brillouin-zone sampling and other sources of technical error. Results for the radial distribution function, the diffusion coefficient and the shear viscosity are presented for a wide range of thermodynamic states relevant to the Earth's core. Throughout this range, liquid iron is a close-packed simple liquid with a diffusion coefficient and viscosity similar to those of typical simple liquids under ambient conditions.Comment: 13 pages, 8 figure

The Spectrum of Electromagnetic Jets from Kerr Black Holes and Naked Singularities in the Teukolsky Perturbation Theory

We give a new theoretical basis for examination of the presence of the Kerr black hole (KBH) or the Kerr naked singularity (KNS) in the central engine of different astrophysical objects around which astrophysical jets are typically formed: X-ray binary systems, gamma ray bursts (GRBs), active galactic nuclei (AGN), etc. Our method is based on the study of the exact solutions of the Teukolsky master equation for electromagnetic perturbations of the Kerr metric. By imposing original boundary conditions on the solutions so that they describe a collimated electromagnetic outflow, we obtain the spectra of possible {\em primary jets} of radiation, introduced here for the first time. The theoretical spectra of primary electromagnetic jets are calculated numerically. Our main result is a detailed description of the qualitative change of the behavior of primary electromagnetic jet frequencies under the transition from the KBH to the KNS, considered here as a bifurcation of the Kerr metric. We show that quite surprisingly the novel spectra describe linearly stable primary electromagnetic jets from both the KBH and the KNS. Numerical investigation of the dependence of these primary jet spectra on the rotation of the Kerr metric is presented and discussed.Comment: 18 pages, 35 figures, LaTeX file. Final version. Accepted for publication in Astrophysics and Space Science. Amendments. Typos corrected. Novel notion -"primary jet" is introduced. New references and comments adde

Mathematics of Gravitational Lensing: Multiple Imaging and Magnification

The mathematical theory of gravitational lensing has revealed many generic and global properties. Beginning with multiple imaging, we review Morse-theoretic image counting formulas and lower bound results, and complex-algebraic upper bounds in the case of single and multiple lens planes. We discuss recent advances in the mathematics of stochastic lensing, discussing a general formula for the global expected number of minimum lensed images as well as asymptotic formulas for the probability densities of the microlensing random time delay functions, random lensing maps, and random shear, and an asymptotic expression for the global expected number of micro-minima. Multiple imaging in optical geometry and a spacetime setting are treated. We review global magnification relation results for model-dependent scenarios and cover recent developments on universal local magnification relations for higher order caustics.Comment: 25 pages, 4 figures. Invited review submitted for special issue of General Relativity and Gravitatio