65 research outputs found
Financiële consequenties van staartbijten bij varkens
Report on the financial consequences of tail damage due to tail biting among pigs in conventional pig farms in the Netherlands
Health-related quality of life of long-term high-grade glioma survivors
The objective of this study was to compare the health-related quality of life (HRQOL) of long-term to short-term high-grade glioma (HGG) survivors, determine the prognostic value of HRQOL for overall survival, and determine the effect of tumor recurrence on HRQOL for long-term survivors. Following baseline assessment (after surgery, before radiotherapy), self-perceived HRQOL (using the Medical Outcomes Study Short Form 36 [SF-36]) and brain tumor-specific symptoms (using the 20-item Brain Cancer Module) were assessed every 4 months until 16 months after histological diagnosis. Kaplan-Meier survival analysis and the Cox proportional hazards model were performed to estimate overall survival of patients with impaired scores on the aggregated SF-36 higher-order summary scores measuring physical functioning on a physical component scale and on a mental component scale (MCS). Sixteen patients with a short-term survival (baseline and 4-month follow-up) and 16 with a long-term survival (follow-up until 16 months after diagnosis) were selected out of 68 initially recruited HGG patients. At baseline, the short-term and long-term survivors did not differ in their HRQOL. Between baseline and the 4-month follow-up, HRQOL of short-term survivors deteriorated, whereas the long-term survivors improved to a level comparable to healthy controls. Patients with impaired mental functioning (MCS) at baseline had a shorter median survival than patients with normal functioning. After accounting for differences in patient and tumor characteristics, however, mental functioning was not independently related to poorer overall survival. Not surprisingly, in the group of long-term survivors, the five patients with recurrence had a more compromised HRQOL at the 16-month follow-up compared to the 11 patients without recurrence. We concluded that baseline HRQOL is not related to duration of survival and that long-term survivors show improvement of HRQOL to a level comparable to that of the healthy
Research Programme to Improve the Utilization of Home-Grown forages in the Netherlands
In The Netherlands a research programme has been initiated by the Ministry of Agriculture, Nature Management and Fisheries to increase the proportion of high-quality home-grown forage in rations for dairy cows. This should result in a more sustainable dairy husbandry by improving the efficiency of utilization of nitrogen and phosphorus from home-grown forages (mainly grass and maize) on farm level. Research disciplines involved are plant breeding, forage harvesting and conservation and nutrition
Targeting of mitochondrial reactive oxygen species production does not avert lipid-induced insulin resistance in muscle tissue from mice.
Dark mammoth trunks in the merging galaxy NGC 1316 and a mechanism of cosmic double helices
NGC 1316 is a giant, elliptical galaxy containing a complex network of dark,
dust features. The morphology of these features has been examined in some
detail using a Hubble Space Telescope, Advanced Camera for Surveys image. It is
found that most of the features are constituted of long filaments. There also
exist a great number of dark structures protruding inwards from the filaments.
Many of these structures are strikingly similar to elephant trunks in H II
regions in the Milky Way Galaxy, although much larger. The structures, termed
mammoth trunks, generally are filamentary and often have shapes resembling the
letters V or Y. In some of the mammoth trunks the stem of the Y can be resolved
into two or more filaments, many of which showing signs of being intertwined. A
model of the mammoth trunks, related to a recent theory of elephant trunks, is
proposed. Based on magnetized filaments, the model is capable of giving an
account of the various shapes of the mammoth trunks observed, including the
twined structures.Comment: Accepted for publication in Astrophysics & Space Scienc
Factors Associated with Revision Surgery after Internal Fixation of Hip Fractures
Background: Femoral neck fractures are associated with high rates of revision surgery after management with internal fixation. Using data from the Fixation using Alternative Implants for the Treatment of Hip fractures (FAITH) trial evaluating methods of internal fixation in patients with femoral neck fractures, we investigated associations between baseline and surgical factors and the need for revision surgery to promote healing, relieve pain, treat infection or improve function over 24 months postsurgery. Additionally, we investigated factors associated with (1) hardware removal and (2) implant exchange from cancellous screws (CS) or sliding hip screw (SHS) to total hip arthroplasty, hemiarthroplasty, or another internal fixation device. Methods: We identified 15 potential factors a priori that may be associated with revision surgery, 7 with hardware removal, and 14 with implant exchange. We used multivariable Cox proportional hazards analyses in our investigation. Results: Factors associated with increased risk of revision surgery included: female sex, [hazard ratio (HR) 1.79, 95% confidence interval (CI) 1.25-2.50; P = 0.001], higher body mass index (fo
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