40 research outputs found
Management of lymphedema of the male genitalia
Polysubstituted
cyclopentadienyl and indenyl complexes of ruthenium were synthesized
and investigated to elucidate their potential cytotoxic activities.
In particular, substituted (indenyl)ruthenium complexes inhibited
the proliferation of a panel of human adherent cancer cells with comparable
activity to reference agent cisplatin. One of the active compounds
exerted a concentration dependent inhibition of cell cycle at G1–S
transiton as evidenced by flow cytometry