21 research outputs found
Rms-flux relation of Cyg X-1 with RXTE: dipping and nondipping cases
The rms (root mean square) variability is the parameter for understanding the
emission temporal properties of X-ray binaries (XRBs) and active galactic
nuclei (AGN).
The rms-flux relation with Rossi X-ray Timing Explorer (RXTE) data for the
dips and nondip of black hole Cyg X-1 has been investigated in this paper. Our
results show that there exist the linear rms-flux relations in the frequency
range 0.1-10 Hz for the dipping light curve. Moreover, this linear relation
still remains during the nondip regime, but with the steeper slope than that of
the dipping case in the low energy band. For the high energy band, the slopes
of the dipping and nondipping cases are hardly constant within errors. The
explanations of the results have been made by means of the ``Propagating
Perturbation'' model of Lyubarskii (1997).Comment: 15 pages, 12 figures, Accepted for publication in Astrophysics &
Space Scienc
Reproducibility in the absence of selective reporting : An illustration from large-scale brain asymmetry research
Altres ajuts: Max Planck Society (Germany).The problem of poor reproducibility of scientific findings has received much attention over recent years, in a variety of fields including psychology and neuroscience. The problem has been partly attributed to publication bias and unwanted practices such as p-hacking. Low statistical power in individual studies is also understood to be an important factor. In a recent multisite collaborative study, we mapped brain anatomical left-right asymmetries for regional measures of surface area and cortical thickness, in 99 MRI datasets from around the world, for a total of over 17,000 participants. In the present study, we revisited these hemispheric effects from the perspective of reproducibility. Within each dataset, we considered that an effect had been reproduced when it matched the meta-analytic effect from the 98 other datasets, in terms of effect direction and significance threshold. In this sense, the results within each dataset were viewed as coming from separate studies in an "ideal publishing environment," that is, free from selective reporting and p hacking. We found an average reproducibility rate of 63.2% (SD = 22.9%, min = 22.2%, max = 97.0%). As expected, reproducibility was higher for larger effects and in larger datasets. Reproducibility was not obviously related to the age of participants, scanner field strength, FreeSurfer software version, cortical regional measurement reliability, or regional size. These findings constitute an empirical illustration of reproducibility in the absence of publication bias or p hacking, when assessing realistic biological effects in heterogeneous neuroscience data, and given typically-used sample sizes
Partitioning the Heritability of Tourette Syndrome and Obsessive Compulsive Disorder Reveals Differences in Genetic Architecture
The direct estimation of heritability from genome-wide common variant data as implemented in the program Genome-wide Complex Trait Analysis (GCTA) has provided a means to quantify heritability attributable to all interrogated variants. We have quantified the variance in liability to disease explained
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Properties of multiple event gamma ray bursts
We present results from a study of 37 multiple event gamma ray bursts found in the monitoring data of the PVO gamma ray burst detector. We define these bursts as those which have two or more distinct emission events separated by a return to the background intensity. Significant correlation exists between the duration of the first event and the duration of the second event, while some correlation exists between the hardness of the events and only weak correlation exists in the intensity of the events. Although the time profiles of events in a burst may be similar, as measured in the phase portrait, there is no general rule about the degree of similarity of the time profiles. Subdividing the data according to the recurrence time, we find a tendency for the strength of the correlation in the hardness to increase with decreasing separation between the events. 2 refs., 2 figs., 1 tab
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A slit aperture for the monitoring x-ray experiment (MOXE)
We have investigated a slit aperture as an alternative to the square pinhole aperture for the MOXE detectors, which are to be put on the Soviet satellite Spectrum X-Gamma. A slit offers advantages for better discrimination of sources in crowded regions, eliminates the need for support structures for the aperture window, and does not compromise the signal-to-noise (S/N) of a point source. We find that in a single 24 hr pointing of the satellite, MOXE can determine the position of a 10 mCrab source to better than 0.5{degree} with the slit. The structure of a titanium grate which supports the detector's beryllium window constrains the slit to be 0.5 cm {times} 2.56 cm, oriented at an angle of 26.6{degree} to either side of the center lines of the detector. We illustrate an arrangement of the slits on each of the six detectors which optimizes source localization for a number of pointings. 4 refs., 8 figs., 4 tabs
Hoarding in obsessive-compulsive disorder: Clinical and genetic correlates
Objective: Hoarding may be an important symptom dimension in obsessive-compulsive disorder (OCD). Hoarding in OCD has been associated with poor insight, poorer response to selective serotonin reuptake inhibitors than other OCD symptom dimensions, and a distinctive psychobiological profile. The clinical and genetic correlates of hoarding in OCD therefore deserve additional investigation. Method: Adult OCD patients (N = 315) underwent a comprehensive clinical assessment that included the Structured Clinical Interview for DSM-IV Axis I Disorders (Patient Edition) and for Diagnosis of Obsessive-Compulsive Spectrum Disorders. DNA extracted from venous blood (10-30 mL) in a Caucasian subset of the interviewed OCD patients (N = 204) and Caucasian controls (N = 169), including patients (N = 94) and controls (N = 138) of Afrikaner descent, was genotyped to investigate polymorphisms in genes involved in monoamine function and previously hypothesized to be relevant to OCD. Data were collected from 1998 through 2004. Results: OCD patients with hoarding made up 18.1% of the total sample. Compared with nonhoarding OCD, OCD with hoarding was associated with a number of comorbid Axis I disorders, obsessive-compulsive personality disorder, significantly higher OCD severity scores, and more functional impairment. In subjects of Afrikaner descent, the L/L genotype of the COMT Val158Met polymorphism was significantly more common in the OCD hoarding group, with a preponderance of low activity alleles, compared with nonhoarding patients and controls. Conclusions: These data are consistent with the hypothesis that hoarding represents a unique symptom subtype in OCD with a distinctive clinical and psychobiological profile. Further work is needed to determine the psychobiological mechanisms responsible for hoarding and to replicate the genetic findings noted here.Articl