Dopant-induced crossover from 1D to 3D charge transport in conjugated polymers

The interplay between inter- and intrachain charge transport in bulk polythiophene in the hopping regime has been clarified by studying the conductivity s as a function of frequency ¿/2p (up to 3 THz), temperature T, and doping level c. We present a model which quantitatively explains the observed crossover from quasi-one-dimensional transport to three-dimensional hopping conduction with increasing doping level. At high frequencies the conductivity is dominated by charge transport on one-dimensional conducting chains

The conductivity and band structure of some synthetic semiconductors based on M(dmit)2 (M = Ni, Pd, Pt)

The conductivity of the following six new low-dimensional compounds is reported: (Me4N)(Ni(dmit)2), (Et4N)(Ni(dmit)2), (Pr4N)(Ni(dmit)2), (Bu4N)(Ni(dmit)2), (Bu4N)(Pt(dmit)2) and (Et4N)0.5(Pd(dmit)2). Semiconducting behaviour is found for all the compounds investigated, with activation energies between 0.1 and 0.5 eV. The crystal structures have been established by X-ray diffraction. Using these, the band structure has been determined. It is shown that the compounds investigated are semiconductors each having a correlation gap resulting from an effective electron-electron repulsion of 1.0 eV

Measurement of the complex dielectric constant down to helium temperatures. I. Reflection method from 1 MHz to 20 GHz using an open ended coaxial line

Metals in Catalysis, Biomimetics & Inorganic Material

Measurement of the complex dielectric constant down to helium temperatures. II. Quasi-optical technique from 0.03 to 1 THz

Metals in Catalysis, Biomimetics & Inorganic Material

Platinum(II) compounds with chelating ligands based on pyridine and pyrimidine: synthesis, characterizations, DFT calculations, cytotoxic assays and binding to a DNA model base

Solid state NMR/Biophysical Organic Chemistr

The metallic state in disordered quasi-one-dimensional conductors

The unusual metallic state in conjugated polymers and single-walled carbon nanotubes is studied by dielectric spectroscopy (8--600 GHz). We have found an intriguing correlation between scattering time and plasma frequency. This relation excludes percolation models of the metallic state. Instead, the carrier dynamics can be understood in terms of the low density of delocalized states around the Fermi level, which arises from the competion between disorder-induced localization and interchain-interactions-induced delocalization.Comment: 4 pages including 4 figure

An efficient conjugation approach for coupling drugs to native antibodies via the PtII linker Lx for improved manufacturability of antibody–drug conjugates

The Pt-II linker [ethylenediamineplatinum(II)](2+), coined Lx, has emerged as a novel non-conventional approach to antibody-drug conjugates (ADCs) and has shown its potential in preclinical in vitro and in vivo benchmark studies. A crucial improvement of the Lx conjugation reaction from initially <15 % to ca. 75-90 % conjugation efficiency is described, resulting from a systematic screening of all relevant reaction parameters. NaI, a strikingly simple inorganic salt additive, greatly improves the conjugation efficiency as well as the conjugation selectivity simply by exchanging the leaving chloride ligand on Cl-Lx-drug complexes (which are direct precursors for Lx-ADCs) for iodide, thus generating I-Lx-drug complexes as more reactive species. Using this iodide effect, we developed a general and highly practical conjugation procedure that is scalable: our lead Lx-ADC was produced on a 5 g scale with an outstanding conjugation efficiency of 89 %.Metals in Catalysis, Biomimetics & Inorganic Material