The Frenchness of Marcel Lefebvre and the Society of St Pius X:a new reading

The case of Marcel Lefebvre and the Society of St Pius X (SSPX) deserves fresh perspectives. The current historiography is too franco-centric, focused on selective aspects of Lefebvre’s biography and the actions of isolated individuals, rather than with the life of the SSPX itself. After evaluating the current state of the historiography, this article proposes a new analysis of the SSPX’s political discourses in France and internationally and undertakes to reframe the relationship between Lefebvre’s life and his congregation by re-examining his African missionary experiences. Such new perspectives will be helpful as the SSPX moves towards regularisation under the pontificate of Pope Francis

Etude et réalisation d'un détecteur d'électrons rétrodiffusés à faible bruit pour l'imagerie in situ

A backscattered electron detector (BSE) with flexible light pipe utilizing optical fibres between the scintillator and the photomultiplier tube was constructed and set up in our transportable scanning microscope (MEBIS). It has a good detection quantum efficiency (DQE), a large bandwidth and is well adapted for chemical characterisation of bulk specimens.Un détecteur d'électrons rétrodiffusés (BSE) avec une liaison flexible par faisceau de fibres optiques entre le scintillateur et le photomultiplicateur a été élaboré et installé dans notre Microscope Electronique à Balayage In Situ (MEBIS). Il possède une bonne efficacité quantique de détection (DQE), une large bande passante et une résolution en numéro atomique $Z$ bien adaptée à la caractériation chimique de la surface des échantillons massifs étudiés

Acute lymphoblastic leukemia relapsing after first-line pediatric-inspired therapy: a retrospective GRAALL study

International audienceThe outcome of adult patients with Philadelphia chromosome-negative acute lymphoblastic leukemia (Ph- ALL) relapsing after pediatric-inspired front-line therapy is ill known. Here 229 relapsing Ph- ALL younger adults (18-63 years) treated within the Group for Research on Adult Acute Lymphoblastic Leukemia (GRAALL)-2003/-2005 trials were considered. Salvage regimens consisted of potentially curative therapies in 194 cases, low-intensity therapies in 21, allogeneic stem cell transplant (allo-SCT) in 6 and best supportive care in 8. Overall, 77 patients received allo-SCT after relapse. The median follow-up was 3.1 years. A second complete remission (CR2) was achieved in 121 patients (53%). In multivariate analysis, only younger age \textless45 years (P=0.008) and CR1 duration 18 months (P=0.009) predicted CR2. Overall survival (OS) at 2 and 5 years was 19.3% (14-24%) and 13.3% (8-18%), respectively. In CR2 patients, disease-free survival (DFS) at 2 and 5 years was 29.0% (21-38%) and 25% (17-33%). In multivariate analysis, CR1 duration 18 months and allo-SCT after relapse were associated with longer DFS (P\textless0.009 and P=0.004, respectively) and longer OS (P=0.004 and P\textless0.0001, respectively). In conclusion, although younger adults relapsing after pediatric-inspired ALL therapies retain a poor outcome, some of them may be cured if CR1 duration 18 months and if allo-SCT can be performed in CR2. New therapies are definitely needed for these patient