METAL: fast and efficient meta-analysis of genomewide association scans

Summary: METAL provides a computationally efficient tool for meta-analysis of genome-wide association scans, which is a commonly used approach for improving power complex traits gene mapping studies. METAL provides a rich scripting interface and implements efficient memory management to allow analyses of very large data sets and to support a variety of input file formats

Shaping concepts of technology : what concepts and how to shape them?

Philosophy of technology is a discipline that has much to offer for technology education. Insights into the real nature of technology and its relationship with science and society can help technology educators to build a subject that helps pupils get a good concept of technology and to learn to understand and use concepts in technology. Here the way science educators have gained from the philosophy of science, for example in the idea of the way pupils learn concepts by reconstructing pre-concepts that they picked up from daily-life experiences. Research has shown that the learning of concepts and the learning of process skills have to be connected