The two-pseudoscalar-meson decay of χcJ\chi_{cJ} with twist-3 corrections

The decays of $\chi_{cJ} \to \pi^+\pi^-, K^+K^-$ $(J=0,2)$ are discussed within the standard and modified hard scattering approach when including the contributions from twist-3 distribution amplitudes and wave functions of the light pseudoscalar meson. A model for twist-2 and twist-3 distribution amplitudes and wave functions of the pion and kaon with BHL prescription are proposed as the solution to the end-point singularities. The results show that the contributions from twist-3 parts are actually not power suppressed comparing with the leading-twist contribution. After including the effects from the transverse momentum of light meson valence-quark state and Sudakov factors, the decay widths of the $\chi_{cJ}$ into pions or kaons are comparable with the their experimental data.Comment: 31 pages, 5 figures, 3 table

Simulation Study on neutrino nucleus cross section measurement in Segmented Detector at Spallation Neutron Source

Knowledge of $\nu_e$-$\mathrm{Fe}/\mathrm{Pb}$ differential cross sections for $\nu_e$ energy below several tens of MeV scale is believed to be crucial in understanding Supernova physics. In a segmented detector at Spallation Neutrino Source, $\nu_e$ energy reconstructed from the electron range measurement is strongly affected because of both multiple scattering and electromagnetic showers occurring along the electron passage in target materials. In order to estimate the effect, a simulation study has been performed with a cube block model assuming a perfect tracking precision. The distortion of energy spectrum is observed to be proportional to the atomic number of target material. Feasibility of unfolding the distorted $\nu_e$ energy spectrum is studied for both Fe and Pb cases. Evaluation of statistical accuracy attainable is therefore provided for a segmented detector.Comment: 6 pages, 6 figures, submitted to Chinese Physics

X-ray Observation and Analysis of The Composite Supernova Remnant G327.1-1.1

Based on the data from the observation of the SNR G327.1-1.1 by ASCA and ROSAT, we find that G327.1-1.1 is a composite remnant with both a nonthermal emission component and a diffuse thermal emission component. The nonthermal component is well fitted by a power-law model with photon index about 2.2. This component is attributed to the emission from the synchrotron nebula powered by an undiscovered central pulsar. The thermal component has a temperature of about 0.4 keV. We attribute it to the emission from the shock-heat swept-up ISM. Its age, explosion energy and density of ambient medium are derived from the observed thermal component. Some charactistics about the synchrotron nebula are also derived. We search for the pulsed signal, but has not found it. The soft X-ray(0.4 - 2 keV) and hard X-ray(2 - 10 keV) images are different, but they both elongate in the SE-NW direction. And this X-ray SE-NW elongation is in positional coincidence with the radio ridge in MOST 843MHz radio map. We present a possibility that the X-ray nonthermal emission mainly come from the trail produced by a quickly moving undiscoverd pulsar, and the long radio ridge is formed when the pulsar is moving out of the boundary of the plerionic structure.Comment: 20 pages, 4 Postscript figures, aasms4.sty and psfig.sty, to be published in Astrophysical Journal, January 20, 1999, Vol. 51

An analysis of the X-ray emission from the supernova remnant 3C397

The ASCA SIS and the ROSAT PSPC spectral data of the SNR 3C397 are analysed with a two-component non-equilibrium ionization model. Besides, the ASCA SIS0 and SIS1 spectra are also fitted simultaneously in an equilibrium case. The resulting values of the hydrogen column density yield a distance of \sim8\kpc to 3C397. It is found that the hard X-ray emission, containing S and Fe K$\alpha$ lines, arises primarily from the hot component, while most of the soft emission, composed mainly of Mg, Si, Fe L lines, and continuum, is produced by the cool component. The emission measures suggest that the remnant evolves in a cloudy medium and imply that the supernova progenitor might not be a massive early-type star. The cool component is approaching ionization equilibrium. The ages estimated from the ionization parameters and dynamics are all much greater than the previous determination. We restore the X-ray maps using the ASCA SIS data and compare them with the ROSAT HRI and the NRAO VLA Sky Survey (NVSS) 20 cm maps. The morphology with two bright concentrations suggests a bipolar remnant encountering a denser medium in the west.Comment: 20 pages, aasms4.sty, 3 figures To appear in ApJ (1999

Divergent functions for airway epithelial matrix metalloproteinase 7 and retinoic acid in experimental asthma.

The innate immune response of airway epithelial cells to airborne allergens initiates the development of T cell responses that are central to allergic inflammation. Although proteinase allergens induce the expression of interleukin 25, we show here that epithelial matrix metalloproteinase 7 (MMP7) was expressed during asthma and was required for the maximum activity of interleukin 25 in promoting the differentiation of T helper type 2 cells. Allergen-challenged Mmp7(-/-) mice had less airway hyper-reactivity and production of allergic inflammatory cytokines and higher expression of retinal dehydrogenase 1. Inhibition of retinal dehydrogenase 1 restored the asthma phenotype of Mmp7(-/-) mice and inhibited the responses of lung regulatory T cells, whereas exogenous administration of retinoic acid attenuated the asthma phenotype. Thus, MMP7 coordinates allergic lung inflammation by activating interleukin 25 while simultaneously inhibiting retinoid-dependent development of regulatory T cells

Versatile Roles of V-ATPases Accessory Subunit Ac45 in Osteoclast Formation and Function

Vacuolar-type H+-ATPases (V-ATPases) are macromolecular proton pumps that acidify intracellular cargos and deliver protons across the plasma membrane of a variety of specialized cells, including bone-resorbing osteoclasts. Extracellular acidification is crucial for osteoclastic bone resorption, a process that initiates the dissolution of mineralized bone matrix. While the importance of V-ATPases in osteoclastic resorptive function is well-defined, whether V-ATPases facilitate additional aspects of osteoclast function and/or formation remains largely obscure. Here we report that the V-ATPase accessory subunit Ac45 participates in both osteoclast formation and function. Using a siRNA-based approach, we show that targeted suppression of Ac45 impairs intracellular acidification and endocytosis, both are prerequisite for osteoclastic bone resorptive function in vitro. Interestingly, we find that knockdown of Ac45 also attenuates osteoclastogenesis owing to a reduced fusion capacity of osteoclastic precursor cells. Finally, in an effort to gain more detailed insights into the functional role of Ac45 in osteoclasts, we attempted to generate osteoclast-specific Ac45 conditional knockout mice using a Cathepsin K-Cre-LoxP system. Surprisingly, however, insertion of the neomycin cassette in the Ac45-FloxNeo mice resulted in marked disturbances in CNS development and ensuing embryonic lethality thus precluding functional assessment of Ac45 in osteoclasts and peripheral bone tissues. Based on these unexpected findings we propose that, in addition to its canonical function in V-ATPase-mediated acidification, Ac45 plays versatile roles during osteoclast formation and function

Spin-glass ground state in a triangular-lattice compound YbZnGaO4_4

We report on comprehensive results identifying the ground state of a triangular-lattice structured YbZnGaO$_4$ to be spin glass, including no long-range magnetic order, prominent broad excitation continua, and absence of magnetic thermal conductivity. More crucially, from the ultralow-temperature a.c. susceptibility measurements, we unambiguously observe frequency-dependent peaks around 0.1 K, indicating the spin-glass ground state. We suggest this conclusion to hold also for its sister compound YbMgGaO$_4$, which is confirmed by the observation of spin freezing at low temperatures. We consider disorder and frustration to be the main driving force for the spin-glass phase.Comment: Version as accepted to PR