Light charged Higgs boson production at the Large Hadron electron Collider

We study the production of a light charged Higgs boson at the future Large Hadron electron Collider (LHeC), through the process $e^- p \to \nu_e H^- q$ considering both decay channels $H^- \to b \bar c$ and $H^- \to \tau \bar \nu_\tau$ in the final state. We analyse these processes in the context of the 2-Higgs Doublet Model Type III (2HDM-III) and assess the LHeC sensitivity to such $H^-$ signals against a variety of both reducible and irreducible backgrounds. We confirm that prospects for $H^-$ detection in the 2HDM-III are excellent assuming standard collider energy and luminosity conditions.Comment: 12 pages, 12 figures. Accepted in Physical Review

Effects of physics beyond the standard model on the neutrino charge radius: an effective Lagrangian approach

In this work, we look for possible new physics effects on the electromagnetic charge and anapole form factors, $f_Q(q^2)$ and $f_A(q^2)$, for a massless Dirac neutrino, when these quantities are calculated in the context of an effective electroweak Yang-Mills theory, which induces the most general $SU_L(2)$--invariant Lorentz tensor structure of nonrenormalizable type for the $WW\gamma$ vertex. It is found that in this context, besides the standard model contribution, the additional contribution to $f_{Q}(q^2)$ and $f_{A}(q^2)$ ($f_{Q}^{O_W}(q^2)$ and $f_{A}^{O_W}(q^2)$, respectively) are gauge independent and finite functions of $q^2$ after adopting a renormalization scheme. These form factors, $f_{Q}^{O_W}(q^2)$ and $f_{A}^{O_W}(q^2)$, get contribution at the one loop level only from the proper neutrino electromagnetic vertex. Besides, the relation $f_{Q}^{eff}(q^2)=q^2f_{A}^{eff}(q^2)$ ($f_{Q}^{eff}(q^2)=f_{Q}^{SM}(q^2)+f_{Q}^{O_W}(q^2)$, $f_{A}^{eff}(q^2)=f_{A}^{SM}(q^2)+f_{A}^{O_W}(q^2)$) is still fulfilled and hence the relation $a_{\nu}^{eff} = ^{eff} /6$ ($a_{\nu}^{eff} = a_{\nu}^{SM}+ a_{\nu}^{O_W}$, $^{eff} = ^{SM}+< r^2_{\nu} > ^{O_W}$)is gotten, just as in the SM. Using the experimental constraint on the anomalous $WW\gamma$ vertex, a value for the additional contribution to the charge radius of |^{O_W}| \lsim 10^{-34} cm^2 is obtained, which is one order of magnitude lower than the SM value.Comment: 9 pages, 3 figure

Orai2 Modulates Store-Operated Ca2+ Entry and Cell Cycle Progression in Breast Cancer Cells

Breast cancer is a heterogeneous disease from the histological and molecular expression point of view, and this heterogeneity determines cancer aggressiveness. Store-operated Ca2+ entry (SOCE), a major mechanism for Ca2+ entry in non-excitable cells, is significantly remodeled in cancer cells and plays an important role in the development and support of different cancer hallmarks. The store-operated CRAC (Ca2+ release-activated Ca2+) channels are predominantly comprised of Orai1 but the participation of Orai2 and Orai3 subunits has been reported to modulate the magnitude of Ca2+ responses. Here we provide evidence for a heterogeneous expression of Orai2 among different breast cancer cell lines. In the HER2 and triple negative breast cancer cell lines SKBR3 and BT20, respectively, where the expression of Orai2 was greater, Orai2 modulates the magnitude of SOCE and sustain Ca2+ oscillations in response to carbachol. Interestingly, in these cells Orai2 modulates the activation of NFAT1 and NFAT4 in response to high and low agonist concentrations. Finally, we have found that, in cells with high Orai2 expression, Orai2 knockdown leads to cell cycle arrest at the G0-G1 phase and decreases apoptosis resistance upon cisplatin treatment. Altogether, these findings indicate that, in breast cancer cells with a high Orai2 expression, Orai2 plays a relevant functional role in agonist-evoked Ca2+ signals, cell proliferation and apoptosis resistance.Ministerio de Ciencia e Innovación: PID2019-104084GB-C21Ministerio de Ciencia e Innovación: PID2019-104084GB-C22Consejería de Educación y Empleo, Junta de Extremadura: IB20007Consejería de Educación y Empleo, Junta de Extremadura: GR18061Consejería de Educación y Empleo, Junta de Extremadura: PD16072Consejería de Educación y Empleo, Junta de Extremadura: GR2100

Yukawa txtures and charged Higgs boson phenomenology in the type-III two-Higgs-doublet model

We discuss the implications of assuming a four-zero Yukawa texture for the properties of the charged Higgs boson within the context of the general 2-Higgs Doublet Model of Type III. We begin by presenting a detailed analysis of the charged Higgs boson couplings with heavy quarks and the resulting pattern for its decays. The production of charged Higgs bosons is also sensitive to the modifications of its couplings, so that we also evaluate the resulting effects on the top decay $t \to b H^{+}$ as well as on `direct' $c\bar{b}\to H^++c. c.$ and `indirect' $q\bar q,gg\to \bar t b H^++c. c.$ production. Significant scope exists at the Large Hadron Collider for several $H^\pm$ production and decay channels combined to enable one to distinguish between such a model and alternative 2-Higgs doublet scenarios.Comment: 30 pages, 18 figure

Tratado de derechos reales. Tomo II Propiedad y posesión

La presente investigación está referida al análisis de los dos principales derechos reales: la posesión y la propiedad, y es la continuación de la investigación concluida denominada Tratado de derechos reales, tomo I, teoría de los bienes y los derechos reales. Esta parte de la investigación corresponde al desarrollo de dos de sus principales instituciones. Así, se comienza con el análisis sociojurídico de la posesión (poder hecho) como derecho transitorio (temporal y momentáneo), para luego entrar al desarrollo de la propiedad (poder de derecho) como derecho definitivo (permanente y total), ambas instituciones reconocidas como situaciones jurídicas de gran trascendencia en las relaciones jurídicas patrimoniales, protegidas por la ley a través de mecanismos de defensa