A Flexible Implementation of a Matrix Laurent Series-Based 16-Point Fast Fourier and Hartley Transforms

This paper describes a flexible architecture for implementing a new fast computation of the discrete Fourier and Hartley transforms, which is based on a matrix Laurent series. The device calculates the transforms based on a single bit selection operator. The hardware structure and synthesis are presented, which handled a 16-point fast transform in 65 nsec, with a Xilinx SPARTAN 3E device.Comment: 4 pages, 4 figures. IEEE VI Southern Programmable Logic Conference 201

Organização da diversidade de acessos de mandioca com alta similaridade genética com base em marcadores SNPs e microssatélites.

O fato de a mandioca (Manihot esculenta Crantz) ser uma planta nativa do Brasil e a ampla gama de locais de cultivo no país amplificam a diversidade fenotípica observada nos acessos de germoplasma desta espécie. Por outro lado, muitos nomes são dados a um mesmo genótipo e ao mesmo tempo diferentes acessos possuem um mesmo nome

The gut microbiota, bile acids and their correlation in primary sclerosing cholangitis associated with inflammatory bowel disease.

BACKGROUND: Patients with primary sclerosing cholangitis associated with inflammatory bowel disease (PSC-IBD) have a very high risk of developing colorectal neoplasia. Alterations in the gut microbiota and/or gut bile acids could account for the increase in this risk. However, no studies have yet investigated the net result of cholestasis and a potentially altered bile acid pool interacting with a dysbiotic gut flora in the inflamed colon of PSC-IBD. AIM: The aim of this study was to compare the gut microbiota and stool bile acid profiles, as well as and their correlation in patients with PSC-IBD and inflammatory bowel disease alone. METHODS: Thirty patients with extensive colitis (15 with concomitant primary sclerosing cholangitis) were prospectively recruited and fresh stool samples were collected. The microbiota composition in stool was profiled using bacterial 16S rRNA sequencing. Stool bile acids were assessed by high-performance liquid chromatography tandem mass spectrometry. RESULTS: The total stool bile acid pool was significantly reduced in PSC-IBD. Although no major differences were observed in the individual bile acid species in stool, their overall combination allowed a good separation between PSC-IBD and inflammatory bowel disease. Compared with inflammatory bowel disease alone, PSC-IBD patients demonstrated a different gut microbiota composition with enrichment in Ruminococcus and Fusobacterium genus compared with inflammatory bowel disease. At the operational taxonomic unit level major shifts were observed within the Firmicutes (73%) and Bacteroidetes phyla (17%). Specific microbiota-bile acid correlations were observed in PSC-IBD, where 12% of the operational taxonomic units strongly correlated with stool bile acids, compared with only 0.4% in non-PSC-IBD. CONCLUSIONS: Patients with PSC-IBD had distinct microbiota and microbiota-stool bile acid correlations as compared with inflammatory bowel disease. Whether these changes are associated with, or may predispose to, an increased risk of colorectal neoplasia needs to be further clarified.info:eu-repo/semantics/publishedVersio