An analysis method for time ordered data processing of Dark Matter experiments

The analysis of the time ordered data of Dark Matter experiments is becoming more and more challenging with the increase of sensitivity in the ongoing and forthcoming projects. Combined with the well-known level of background events, this leads to a rather high level of pile-up in the data. Ionization, scintillation as well as bolometric signals present common features in their acquisition timeline: low frequency baselines, random gaussian noise, parasitic noise and signal characterized by well-defined peaks. In particular, in the case of long-lasting signals such as bolometric ones, the pile-up of events may lead to an inaccurate reconstruction of the physical signal (misidentification as well as fake events). We present a general method to detect and extract signals in noisy data with a high pile-up rate and qe show that events from few keV to hundreds of keV can be reconstructed in time ordered data presenting a high pile-up rate. This method is based on an iterative detection and fitting procedure combined with prior wavelet-based denoising of the data and baseline subtraction. {We have tested this method on simulated data of the MACHe3 prototype experiment and shown that the iterative fitting procedure allows us to recover the lowest energy events, of the order of a few keV, in the presence of background signals from a few to hundreds of keV. Finally we applied this method to the recent MACHe3 data to successfully measure the spectrum of conversion electrons from Co57 source and also the spectrum of the background cosmic muons

MIMAC-He3 : A Micro-TPC Matrix of Chambers of He3 for direct detection of Wimps

The project of a micro-TPC matrix of chambers of \hetrois for direct detection of non-baryonic dark matter is presented. The privileged properties of He3 are highlighted. The double detection (ionization - projection of tracks) is explained and its rejection evaluated. The potentialities of MIMAC-He3 for supersymmetric dark matter search are discussed.Comment: to appear in Proc. of the 9th International Conference on Topics in Astroparticle and Underground Physics (TAUP 2005), Zaragoza, Sept. 200

The role of fiscal rules and institutions in shaping budgetary outcomes

The Workshop "The role of fiscal rules and institutions in shaping budgetary outcomes" organized by the Directorate-General for Economic and Financial affairs of the European Commission on 24 November 2006 in Brussels aimed at enriching the debate on the fiscal arrangements and improving the understanding of their functioning. This Economic Paper contains all the paper presented in this event that was organised in four sessions. A first set of papers mainly focus on the impact of numerical fiscal rules on budgetary outturns. Other paper deal primarily with the appropriate design of fiscal rules and institutions. An additional group of papers addresses the relationship between the fiscal governance approach adopted by the EU Member States and their institutional and political frameworks. Finally the remaining presentations relate more directly to policy experiences. fiscal rules, budget, institutions.fiscal rules, budget, institutions, Ayuso-i-Casals, Deroose, Flores, Moulin

Design of a horizontal neutron reflectometer for the European Spallation Source

A design study of a horizontal neutron reflectometer adapted to the general baseline of the long pulse European Spallation Source (ESS) is presented. The instrument layout comprises solutions for the neutron guide, high-resolution pulse shaping and beam bending onto a sample surface being so far unique in the field of reflectometry. The length of this instrument is roughly 55 m, enabling $\delta \lambda / \lambda$ resolutions from 0.5% to 10%. The incident beam is focussed in horizontal plane to boost measurements of sample sizes of 1*1 cm{^2} and smaller with potential beam deflection in both downward and upward direction. The range of neutron wavelengths untilized by the instrument is 2 to 7.1 (12.2, ...) {\AA}, if every (second, ...) neutron source ulse is used. Angles of incidence can be set between 0{\deg} and 9{\deg} with a total accessible q-range from 4*10^{-3} {\AA}^{-1} up to 1 {\AA}^{-1}. The instrument operates both in {\theta}/{\theta} (free liquid surfaces) and {\theta}/2{\theta} (solid/liquid, air/solid interfaces) geometry. The experimental setup will in particular enable direct studies on ultrathin films (d ~ 10 {\AA}) and buried monolayers to multilayered structures of up to 3000 {\AA} total thickness. The horizontal reflectometer will further foster investigations of hierarchical systems from nanometer to micrometer length scale, as well as their kinetics and dynamical properties, in particular under load (shear, pressure, external fields). Polarization and polarization analysis as well as the GISANS option are designed as potential modules to be implemented separately in the generic instrument layout. The instrument is highly flexible and offers a variety of different measurement modes. With respect to its mechanical components the instrument is exclusively based on current technology. Risks of failure for the chosen setup are minimum.Comment: Matched to the version submitted to Nuclear Instruments and Methods

MACHe3, a prototype for non-baryonic dark matter search: KeV event detection and multicell correlation

Superfluid He3 at ultra-low temperatures (100 microKelvins) is a sensitive medium for the bolometric detection of particles. MACHe3 (MAtrix of Cells of Helium 3) is a project for non-baryonic dark matter search using He3 as a sensitive medium. Simulations made on a high granularity detector show a very good rejection to background signals. A multicell prototype including 3 bolometers has been developed to allow correlations between the cells for background event discrimination. One of the cells contains a low activity Co57 source providing conversion electrons of 7.3 and 13.6 keV to confirm the detection of low energy events. First results on the multicell prototype are presented. A detection threshold of 1 keV has been achieved. The detection of low energy conversion electrons coming from the Co57 source is highlighted as well as the cosmic muon spectrum measurement. The possibility to reject background events by using the correlation among the cells is demonstrated from the simultaneous detection of muons in different cells

Apoptosis Modulation as a Promising Target for Treatment of Systemic Sclerosis

Diffuse systemic sclerosis (SSc) is a fatal autoimmune disease characterized by an excessive ECM deposition inducing a loss of function of skin and internal organs. Apoptosis is a key mechanism involved in all the stages of the disease: vascular damage, immune dysfunction, and fibrosis. The purpose of this paper is to gather new findings in apoptosis related to SSc, to highlight relations between apoptosis and fibrosis, and to identify new therapeutic targets

Reflexion M\"ossbauer analysis of the in situ oxidation products hydroxycarbonate green rust

The purpose of this study is to determine the nature of the oxidation products of FeII-III hydroxycarbonate FeII4FeIII2(OH)12CO3~3H2O (green rust GR(CO32-)) by using the miniaturised M\"ossbauer spectrometer MIMOS II. Two M\"ossbauer measurements methods are used: method (i) with green rust pastes coated with glycerol and spread into Plexiglas sample holders, and method (ii) with green rust pastes in the same sample holders but introduced into a gas-tight cell with a beryllium window under a continuous nitrogen flow. Method (ii) allows us to follow the continuous deprotonation of GR(CO32-) into the fully ferric deprotonated form FeIII6O4(OH)8CO3~3H2O by adding the correct amount of H2O2, without any further oxidation or degradation of the samples

Embodied Artificial Intelligence through Distributed Adaptive Control: An Integrated Framework

In this paper, we argue that the future of Artificial Intelligence research resides in two keywords: integration and embodiment. We support this claim by analyzing the recent advances of the field. Regarding integration, we note that the most impactful recent contributions have been made possible through the integration of recent Machine Learning methods (based in particular on Deep Learning and Recurrent Neural Networks) with more traditional ones (e.g. Monte-Carlo tree search, goal babbling exploration or addressable memory systems). Regarding embodiment, we note that the traditional benchmark tasks (e.g. visual classification or board games) are becoming obsolete as state-of-the-art learning algorithms approach or even surpass human performance in most of them, having recently encouraged the development of first-person 3D game platforms embedding realistic physics. Building upon this analysis, we first propose an embodied cognitive architecture integrating heterogenous sub-fields of Artificial Intelligence into a unified framework. We demonstrate the utility of our approach by showing how major contributions of the field can be expressed within the proposed framework. We then claim that benchmarking environments need to reproduce ecologically-valid conditions for bootstrapping the acquisition of increasingly complex cognitive skills through the concept of a cognitive arms race between embodied agents.Comment: Updated version of the paper accepted to the ICDL-Epirob 2017 conference (Lisbon, Portugal

Mesoscale eddies modulate mixed layer depth globally.

Author Posting. © American Geophysical Union, 2019. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Geophysical Research Letters 46(3), (2019):1505-1512, doi:10.1029/2018GL080006.Mesoscale eddies, energetic vortices covering nearly a third of the ocean surface at any one time, modulate the spatial and temporal evolution of the mixed layer. We present a global analysis of concurrent satellite observations of mesoscale eddies with hydrographic profiles by autonomous Argo floats, revealing rich geographic and seasonal variability in the influence of eddies on mixed layer depth. Anticyclones deepen the mixed layer depth, whereas cyclones thin it, with the magnitude of these eddy‐induced mixed layer depth anomalies being largest in winter. Eddy‐centric composite averages reveal that the largest anomalies occur at the eddy center and decrease with distance from the center. Furthermore, the extent to which eddies modulate mixed layer depth is linearly related to the sea surface height amplitude of the eddies. Finally, large eddy‐mediated mixed layer depth anomalies are more common in anticyclones when compared to cyclones. We present candidate mechanisms for this observed asymmetry.This project was supported by NASA grants NNX13AE47G and NNX16AH9G. This manuscript was improved as a result of helpful discussions with Jeffery Early, Johnathan Lilly, and Eric Kunze of Northwest Research Associates. D. J. M. also gratefully acknowledges support of the National Science Foundation. The eddy data set used here is distributed by AVISO at https://www.aviso.altimetry.fr/en/data/products/value-added-products/global-mesoscale-eddy-trajectoryproduct.html. The MLD data can be accessed at http://mixedlayer.ucsd.edu.2019-06-0