Performance of a demand controlled mechanical extract ventilation system for dwellings

The main aim of ventilation is to guarantee a goodindoor air quality, related to the energy consumed forheating and fan(s). Active or passive heat recoverysystems seem to focus on the reduction of heatingconsumption at the expense of fan electricityconsumption and maintenance. In this study, demandcontrolledmechanical extract ventilation systems ofRenson (DCV1 and DCV2), based on natural supply inthe habitable rooms and mechanical extraction in thewet rooms (or even the bedrooms), was analysed forone year by means of multi-zone Contam simulationson a reference detached house and compared withstandard MEV and mechanical extract ventilationsystems with heat recovery (MVHR). To this end, IAQ, total energy consumption,CO2 emissions and total cost of the systems aredetermined. The results show that DCV systems withincreased supply air flow rates or direct mechanicalextract from bedrooms can significantly improve IAQ,while reducing total energy consumption comparedto MEV. Applying DCV reduces primary heatingenergy consumption and yearly fan electricityconsumption at most by 65% to 50% compared toMEV. Total operational energy costs and CO2emissions of DCV are similar when compared toMVHR. Total costs of DCV systems over 15 years aresmaller when compared to MVHR due to lowerinvestment and maintenance costs

Mosaicism of the UDP-Galactose Transporter SLC35A2 Causes a Congenital Disorder of Glycosylation

Biochemical analysis and whole-exome sequencing identified mutations in the Golgi-localized UDP-galactose transporter SLC35A2 that define an undiagnosed X-linked congenital disorder of glycosylation (CDG) in three unrelated families. Each mutation reduced UDP-galactose transport, leading to galactose-deficient glycoproteins. Two affected males were somatic mosaics, suggesting that a wild-type SLC35A2 allele may be required for survival. In infancy, the commonly used biomarker transferrin showed abnormal glycosylation, but its appearance became normal later in childhood, without any corresponding clinical improvement. This may indicate selection against cells carrying the mutant allele. To detect other individuals with such mutations, we suggest transferrin testing in infancy. Here, we report somatic mosaicism in CDG, and our work stresses the importance of combining both genetic and biochemical diagnoses

Salmonellosis with Salmonella typhi murium in the foal

Les auteurs décrivent l’apparition de foyers importants de Salmonel lose équine en France en 1981, provoquant la mort de jeunes poulains de 1 à 3 mois et quelques avortements sur les juments. Le portage par les animaux adultes apparemment sains est important. Cette épidémie de Salmonelloses est due à Salmonella typhimurium V. Copenhague, si cette salmonelle appartient à un biotype particulier (biotype b) connu, elle appartient par contre à un lyzotype encore inconnu en France. Cette salmonelle a d’autre part la particularité d’être multirésistante aux antibiotiques et, de ce fait, les auteurs attirent l’attention des vété rinaires, éleveurs et médecins en leur demandant une grande vigilance et une certaine prudence concernant des traitements intempestifs et « aveu gles » avec des antibiotiques.The authors describe some outbreaks of equine salmonellosis which occured in France during 1981, inducing the death of 1 to 3 months old foals and some abortions on the mares. This epizooty was due to Salmonella typhimurium v. Copenhagen, this salmonella belongs to a special biotype (biotype b) already known but to a lysotype still un know in France. This salmonella has also the characteristic of being multiresistant to antibiotics and the authors draw the attention of the veterinarians, breeders, and physicians on this fact and ask hem to be vigilant and cautions toward the use of «blind» treatements with antibiotics

Testing techniques for straight transonic and supersonic cascades

Tire de : AGARDOGRAPH AR238 on Cascade Testing, Chapter 2, Section 2.5Available at INIST (FR), Document Supply Service, under shelf-number : 22419, issue : a.1992 n.155 / INIST-CNRS - Institut de l'Information Scientifique et TechniqueSIGLEFRFranc